De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation
Ghoneim, Hazem E., Fan, Yiping, Moustaki, Ardiana, Abdelsamed, Hossam A., Dash, Pradyot, Dogra, Pranay, Carter, Robert, Awad, Walid, Neale, Geoff, Thomas, Paul G., Youngblood, Ben
Published in Cell (29.06.2017)
Published in Cell (29.06.2017)
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Origin and differentiation of human memory CD8 T cells after vaccination
Akondy, Rama S, Fitch, Mark, Edupuganti, Srilatha, Yang, Shu, Kissick, Haydn T, Li, Kelvin W, Youngblood, Ben A, Abdelsamed, Hossam A, McGuire, Donald J, Cohen, Kristen W, Alexe, Gabriela, Nagar, Shashi, McCausland, Megan M, Gupta, Satish, Tata, Pramila, Haining, W Nicholas, McElrath, M Juliana, Zhang, David, Hu, Bin, Greenleaf, William J, Goronzy, Jorg J, Mulligan, Mark J, Hellerstein, Marc, Ahmed, Rafi
Published in Nature (London) (21.12.2017)
Published in Nature (London) (21.12.2017)
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PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells
Zheng, Wenting, O'Hear, Carol E, Alli, Rajshekhar, Basham, Jacob H, Abdelsamed, Hossam A, Palmer, Lance E, Jones, Lindsay L, Youngblood, Ben, Geiger, Terrence L
Published in Leukemia (01.05.2018)
Published in Leukemia (01.05.2018)
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The role of self-peptides in direct T cell allorecognition
Abdelsamed, Hossam A, Lakkis, Fadi G
Published in The Journal of clinical investigation (01.11.2021)
Published in The Journal of clinical investigation (01.11.2021)
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Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis
Abdelsamed, Hossam A, Moustaki, Ardiana, Fan, Yiping, Dogra, Pranay, Ghoneim, Hazem E, Zebley, Caitlin C, Triplett, Brandon M, Sekaly, Rafick-Pierre, Youngblood, Ben
Published in The Journal of experimental medicine (05.06.2017)
Published in The Journal of experimental medicine (05.06.2017)
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Generating long‐lived CD8+ T‐cell memory: Insights from epigenetic programs
Dogra, Pranay, Ghoneim, Hazem E., Abdelsamed, Hossam A., Youngblood, Ben
Published in European journal of immunology (01.07.2016)
Published in European journal of immunology (01.07.2016)
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Immunoglobulin-like receptors and the generation of innate immune memory
Al-Moussawy, Mouhamad, Abdelsamed, Hossam A., Lakkis, Fadi G.
Published in Immunogenetics (New York) (01.02.2022)
Published in Immunogenetics (New York) (01.02.2022)
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Beta cell-specific CD8 + T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes
Abdelsamed, Hossam A, Zebley, Caitlin C, Nguyen, Hai, Rutishauser, Rachel L, Fan, Yiping, Ghoneim, Hazem E, Crawford, Jeremy Chase, Alfei, Francesca, Alli, Shanta, Ribeiro, Susan Pereira, Castellaw, Ashley H, McGargill, Maureen A, Jin, Hongjian, Boi, Shannon K, Speake, Cate, Serti, Elisavet, Turka, Laurence A, Busch, Michael E, Stone, Mars, Deeks, Steven G, Sekaly, Rafick-Pierre, Zehn, Dietmar, James, Eddie A, Nepom, Gerald T, Youngblood, Ben
Published in Nature immunology (01.05.2020)
Published in Nature immunology (01.05.2020)
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Epigenetic Maintenance of Acquired Gene Expression Programs during Memory CD8 T Cell Homeostasis
Abdelsamed, Hossam A, Zebley, Caitlin C, Youngblood, Ben
Published in Frontiers in immunology (18.01.2018)
Published in Frontiers in immunology (18.01.2018)
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Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation
Zebley, Caitlin C., Abdelsamed, Hossam A., Ghoneim, Hazem E., Alli, Shanta, Brown, Charmaine, Haydar, Dalia, Mi, Tian, Harris, Tarsha, McGargill, Maureen A., Krenciute, Giedre, Youngblood, Ben
Published in Cell reports (Cambridge) (12.10.2021)
Published in Cell reports (Cambridge) (12.10.2021)
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Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8 + T cell responses
Zamora, Anthony E, Crawford, Jeremy Chase, Allen, E Kaitlynn, Guo, Xi-Zhi J, Bakke, Jesse, Carter, Robert A, Abdelsamed, Hossam A, Moustaki, Ardiana, Li, Yongjin, Chang, Ti-Cheng, Awad, Walid, Dallas, Mari H, Mullighan, Charles G, Downing, James R, Geiger, Terrence L, Chen, Taosheng, Green, Douglas R, Youngblood, Benjamin A, Zhang, Jinghui, Thomas, Paul G
Published in Science translational medicine (26.06.2019)
Published in Science translational medicine (26.06.2019)
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Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation
van der Merwe, Marie, Abdelsamed, Hossam A, Seth, Aman, Ong, Taren, Vogel, Peter, Pillai, Asha B
Published in The Journal of immunology (1950) (01.12.2013)
Published in The Journal of immunology (1950) (01.12.2013)
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Activated-memory T cells influence naïve T cell fate: a noncytotoxic function of human CD8 T cells
Sasaki, Kazuki, Moussawy, Mouhamad Al, Abou-Daya, Khodor I, Macedo, Camila, Hosni-Ahmed, Amira, Liu, Silvia, Juya, Mariam, Zahorchak, Alan F, Metes, Diana M, Thomson, Angus W, Lakkis, Fadi G, Abdelsamed, Hossam A
Published in Communications biology (29.06.2022)
Published in Communications biology (29.06.2022)
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An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis
Abdeltawab, Nourtan F, Aziz, Ramy K, Kansal, Rita, Rowe, Sarah L, Su, Yin, Gardner, Lidia, Brannen, Charity, Nooh, Mohammed M, Attia, Ramy R, Abdelsamed, Hossam A, Taylor, William L, Lu, Lu, Williams, Robert W, Kotb, Malak
Published in PLoS pathogens (01.04.2008)
Published in PLoS pathogens (01.04.2008)
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T-bet controls severity of hypersensitivity pneumonitis
Abdelsamed, Hossam Aly, Desai, Meena, Nance, Stephanie C, Fitzpatrick, Elizabeth A
Published in Journal of inflammation (London, England) (23.06.2011)
Published in Journal of inflammation (London, England) (23.06.2011)
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