Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
Xu, Enquan, Boddu, Ravindra, Abdelmotilib, Hisham A, Sokratian, Arpine, Kelly, Kaela, Liu, Zhiyong, Bryant, Nicole, Chandra, Sidhanth, Carlisle, Samantha M, Lefkowitz, Elliot J, Harms, Ashley S, Benveniste, Etty N, Yacoubian, Talene A, Volpicelli-Daley, Laura A, Standaert, David G, West, Andrew B
Published in Molecular neurodegeneration (10.01.2022)
Published in Molecular neurodegeneration (10.01.2022)
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The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins
Moehle, Mark S, Daher, João Paulo Lima, Hull, Travis D, Boddu, Ravindra, Abdelmotilib, Hisham A, Mobley, James, Kannarkat, George T, Tansey, Malú G, West, Andrew B
Published in Human molecular genetics (01.08.2015)
Published in Human molecular genetics (01.08.2015)
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Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration
Daher, João P.L., Abdelmotilib, Hisham A., Hu, Xianzhen, Volpicelli-Daley, Laura A., Moehle, Mark S., Fraser, Kyle B., Needle, Elie, Chen, Yi, Steyn, Stefanus J., Galatsis, Paul, Hirst, Warren D., West, Andrew B.
Published in The Journal of biological chemistry (07.08.2015)
Published in The Journal of biological chemistry (07.08.2015)
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Alpha-Synuclein Pre-Formed Fibrils Injected into Prefrontal Cortex Primarily Spread to Cortical and Subcortical Structures
Weber, Matthew A., Kerr, Gemma, Thangavel, Ramasamy, Conlon, Mackenzie M., Gumusoglu, Serena B., Gupta, Kalpana, Abdelmotilib, Hisham A., Halhouli, Oday, Zhang, Qiang, Geerling, Joel C., Narayanan, Nandakumar S., Aldridge, Georgina M.
Published in Journal of Parkinson's disease (01.01.2024)
Published in Journal of Parkinson's disease (01.01.2024)
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Pathological [alpha]-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
Xu, Enquan, Boddu, Ravindra, Abdelmotilib, Hisham A, Sokratian, Arpine, Kelly, Kaela, Liu, Zhiyong, Bryant, Nicole, Chandra, Sidhanth, Carlisle, Samantha M, Lefkowitz, Elliot J, Harms, Ashley S, Benveniste, Etty N, Yacoubian, Talene A, Volpicelli-Daley, Laura A, Standaert, David G, West, Andrew B
Published in Molecular neurodegeneration (10.01.2022)
Published in Molecular neurodegeneration (10.01.2022)
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Journal Article
Alpha-synuclein pre-formed fibrils injected into prefrontal cortex primarily spread to cortical and subcortical structures and lead to isolated behavioral symptoms
Weber, Matthew A, Kerr, Gemma, Thangavel, Ramasamy, Conlon, Mackenzie M, Abdelmotilib, Hisham A, Halhouli, Oday, Zhang, Qiang, Geerling, Joel C, Narayanan, Nandakumar S, Aldridge, Georgina M
Published in bioRxiv : the preprint server for biology (15.05.2023)
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Published in bioRxiv : the preprint server for biology (15.05.2023)
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