Identification of a Multi-Messenger RNA Signature as Type 2 Diabetes Mellitus Candidate Genes Involved in Crosstalk between Inflammation and Insulin Resistance
Ali, Hebatalla Said, Boshra, Mariam Sameh, Agwa, Sara H A, Hakeem, Mohamed S Abdel, Meteini, Mahmoud Shawky El, Matboli, Marwa
Published in Biomolecules (Basel, Switzerland) (01.09.2022)
Published in Biomolecules (Basel, Switzerland) (01.09.2022)
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CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB
Bennion, Kelsey B., Liu, Danya, Dawood, Abdelhameed S., Wyatt, Megan M., Alexander, Katie L., Abdel-Hakeem, Mohamed S., Paulos, Chrystal M., Ford, Mandy L.
Published in Nature communications (20.06.2024)
Published in Nature communications (20.06.2024)
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Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects
Mazouz, Sabrina, Salinas, Eduardo, Bédard, Nathalie, Filali, Ali, Khedr, Omar, Swadling, Leo, Abdel-Hakeem, Mohamed S, Siddique, Asiyah, Barnes, Eleanor, Bruneau, Julie, Grakoui, Arash, Shoukry, Naglaa H
Published in PLoS pathogens (15.11.2022)
Published in PLoS pathogens (15.11.2022)
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Analysis of mRNA-miRNA-lncRNA differential expression in prediabetes/type 2 diabetes mellitus patients as potential players in insulin resistance
Ali, Hebatalla Said, Kamel, Marwa Mostafa, Agwa, Sara H A, Hakeem, Mohamed S Abdel, Meteini, Mahmoud Shawky El, Matboli, Marwa
Published in Frontiers in endocrinology (Lausanne) (08.05.2023)
Published in Frontiers in endocrinology (Lausanne) (08.05.2023)
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Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection
Eisa, Mohamed, Gomez-Escobar, Elsa, Bédard, Nathalie, Abdeltawab, Nourtan F, Flores, Nicol, Mazouz, Sabrina, Fieffé-Bédard, Alizée, Sakayan, Patrick, Gridley, John, Abdel-Hakeem, Mohamed S, Bruneau, Julie, Grakoui, Arash, Shoukry, Naglaa H
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
McLane, Laura M, Abdel-Hakeem, Mohamed S, Wherry, E. John
Published in Annual review of immunology (26.04.2019)
Published in Annual review of immunology (26.04.2019)
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Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8+ Memory T Cells
BADR, Gamal, BEDARD, Nathalie, ABDEL-HAKEEM, Mohamed S, TRAUTMANN, Lydie, WILLEMS, Bernard, VILLENEUVE, Jean-Pierre, HADDAD, Elias K, SEKALY, Rafick P, BRUNEAU, Julie, SHOUKRY, Naglaa H
Published in Journal of Virology (01.10.2008)
Published in Journal of Virology (01.10.2008)
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Comparison of Immune Restoration in Early versus Late Alpha Interferon Therapy against Hepatitis C Virus
ABDEL-HAKEEM, Mohamed S, BEDARD, Nathalie, BADR, Gamal, OSTROWSKI, Mario, SEKALY, Rafick P, BRUNEAU, Julie, WILLEMS, Bernard, HEATHCOTE, E. Jenny, SHOUKRY, Naglaa H
Published in Journal of Virology (01.10.2010)
Published in Journal of Virology (01.10.2010)
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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
Beltra, Jean-Christophe, Manne, Sasikanth, Abdel-Hakeem, Mohamed S., Kurachi, Makoto, Giles, Josephine R., Chen, Zeyu, Casella, Valentina, Ngiow, Shin Foong, Khan, Omar, Huang, Yinghui Jane, Yan, Patrick, Nzingha, Kito, Xu, Wei, Amaravadi, Ravi K., Xu, Xiaowei, Karakousis, Giorgos C., Mitchell, Tara C., Schuchter, Lynn M., Huang, Alexander C., Wherry, E. John
Published in Immunity (Cambridge, Mass.) (19.05.2020)
Published in Immunity (Cambridge, Mass.) (19.05.2020)
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Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation
Abdel-Hakeem, Mohamed S., Manne, Sasikanth, Beltra, Jean-Christophe, Stelekati, Erietta, Chen, Zeyu, Nzingha, Kito, Ali, Mohammed-Alkhatim, Johnson, John L., Giles, Josephine R., Mathew, Divij, Greenplate, Allison R., Vahedi, Golnaz, Wherry, E. John
Published in Nature immunology (01.08.2021)
Published in Nature immunology (01.08.2021)
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Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
Giles, Josephine R., Ngiow, Shin Foong, Manne, Sasikanth, Baxter, Amy E., Khan, Omar, Wang, Ping, Staupe, Ryan, Abdel-Hakeem, Mohamed S., Huang, Hua, Mathew, Divij, Painter, Mark M., Wu, Jennifer E., Huang, Yinghui Jane, Goel, Rishi R., Yan, Patrick K., Karakousis, Giorgos C., Xu, Xiaowei, Mitchell, Tara C., Huang, Alexander C., Wherry, E. John
Published in Nature immunology (01.11.2022)
Published in Nature immunology (01.11.2022)
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8 + T cells toward durable effector-like states during chronic antigen exposure
Beltra, Jean-Christophe, Abdel-Hakeem, Mohamed S, Manne, Sasikanth, Zhang, Zhen, Huang, Hua, Kurachi, Makoto, Su, Leon, Picton, Lora, Ngiow, Shin Foong, Muroyama, Yuki, Casella, Valentina, Huang, Yinghui J, Giles, Josephine R, Mathew, Divij, Belman, Jonathan, Klapholz, Max, Decaluwe, Hélène, Huang, Alexander C, Berger, Shelley L, Garcia, K Christopher, Wherry, E John
Published in Immunity (Cambridge, Mass.) (12.12.2023)
Published in Immunity (Cambridge, Mass.) (12.12.2023)
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Expansion of Unique Hepatitis C Virus–Specific Public CD8+ T Cell Clonotypes during Acute Infection and Reinfection
Mazouz, Sabrina, Boisvert, Maude, Abdel-Hakeem, Mohamed S., Khedr, Omar, Bruneau, Julie, Shoukry, Naglaa H.
Published in The Journal of immunology (1950) (15.08.2021)
Published in The Journal of immunology (1950) (15.08.2021)
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