Search Results - "Abdel-Aziz, Alaa A.M." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3 H)-quinazolinone analogs

Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3 H)-quinazolinone analogs

by Al-Rashood, Sarah T., Aboldahab, Ihsan A., Nagi, Mahmoud N., Abouzeid, Laila A., Abdel-Aziz, Alaa A.M., Abdel-hamide, Sami G., Youssef, Khairia M., Al-Obaid, Abdulrahman M., El-Subbagh, Hussein I.
Published in Bioorganic & medicinal chemistry (15.12.2006)

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Synthesis and antitumor evaluation of trimethoxyanilides based on 4(3H)-quinazolinone scaffolds

Synthesis and antitumor evaluation of trimethoxyanilides based on 4(3H)-quinazolinone scaffolds

by Mohamed, Menshawy A., Ayyad, Rezk R., Shawer, Taghreed Z., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S.
Published in European journal of medicinal chemistry (13.04.2016)

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Molecular structure, Hirshfeld surface analysis, spectroscopic (FT-IR, Laser-Raman, UV–vis. and NMR), HOMO-LUMO and NBO investigations on N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-4-methylbenzenesulfonamide

Molecular structure, Hirshfeld surface analysis, spectroscopic (FT-IR, Laser-Raman, UV–vis. and NMR), HOMO-LUMO and NBO investigations on N-(12-amino-9,10-dihydro-9,10-ethanoanthracen-11-yl)-4-methylbenzenesulfonamide

by Alaşalvar, Can, Öztürk, Nuri, Abdel-Aziz, Alaa A.-M., Gökce, Halil, El-Azab, Adel S., El-Gendy, Manal A., Sert, Yusuf
Published in Journal of molecular structure (05.11.2018)

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Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies

Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies

by Abdel-Aziz, Alaa A.-M., Abou-Zeid, Laila A., ElTahir, Kamal Eldin H., Mohamed, Menshawy A., Abu El-Enin, Mohamed A., El-Azab, Adel S.
Published in Bioorganic & medicinal chemistry (15.08.2016)

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Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones

Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones

by Abdel-Aziz, Alaa A.-M., Abou-Zeid, Laila A., ElTahir, Kamal Eldin H., Ayyad, Rezk R., El-Sayed, Magda A.-A., El-Azab, Adel S.
Published in European journal of medicinal chemistry (04.10.2016)

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Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions

Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions

by Abdel-Aziz, Alaa A.-M., Angeli, Andrea, El-Azab, Adel S., Hammouda, Mohammed E.A., El-Sherbeny, Magda A., Supuran, Claudiu T.
Published in Bioorganic chemistry (01.03.2019)

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Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties

Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties

by Angeli, Andrea, Abdel-Aziz, Alaa A.-M., Nocentini, Alessio, El-Azab, Adel S., Gratteri, Paola, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (15.10.2017)

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Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies

Synthesis, anti-inflammatory, analgesic and COX-1/2 inhibition activities of anilides based on 5,5-diphenylimidazolidine-2,4-dione scaffold: Molecular docking studies

by Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., Abou-Zeid, Laila A., ElTahir, Kamal Eldin H., Abdel-Aziz, Naglaa I., Ayyad, Rezk R., Al-Obaid, Abdulrahman M.
Published in European journal of medicinal chemistry (10.06.2016)

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Synthesis, antiproliferative and enzymatic inhibition activities of quinazolines incorporating benzenesulfonamide: Cell cycle analysis and molecular modeling study

Synthesis, antiproliferative and enzymatic inhibition activities of quinazolines incorporating benzenesulfonamide: Cell cycle analysis and molecular modeling study

by El-Azab, Adel S., Alkahtani, Hamad M., AlSaif, Nawaf A., Al-Suwaidan, Ibrahim A., Obaidullah, Ahmad J., Alanazi, Mohammed M., Al-Obaid, Abdulrahman M., Al-Agamy, Mohamed H.M., Abdel-Aziz, Alaa A.-M.
Published in Journal of molecular structure (15.04.2023)

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Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 and/or CDK9

Synthesis and In Vitro Anticancer Activity of Novel 4-Aryl-3-(4-methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridines Arrest Cell Cycle and Induce Cell Apoptosis by Inhibiting CDK2 and/or CDK9

by Almansour, Basma S., Binjubair, Faizah A., Abdel-Aziz, Alaa A.-M., Al-Rashood, Sara T.
Published in Molecules (Basel, Switzerland) (04.09.2023)

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Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives

Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives

by Abdel-Sayed, Maged A., Bayomi, Said M., El-Sherbeny, Magda A., Abdel-Aziz, Naglaa I., ElTahir, Kamal Eldin H., Shehatou, George S.G., Abdel-Aziz, Alaa A.-M.
Published in Bioorganic & medicinal chemistry (01.05.2016)

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Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

by Alanazi, Amer M., El-Azab, Adel S., Al-Suwaidan, Ibrahim A., ElTahir, Kamal Eldin H., Asiri, Yousif A., Abdel-Aziz, Naglaa I., Abdel-Aziz, Alaa A.-M.
Published in European journal of medicinal chemistry (06.03.2015)

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Synthesis, antitumor, and apoptosis-inducing activities of novel 5-arylidenethiazolidine-2,4-dione derivatives: Histone deacetylases inhibitory activity and molecular docking study

Synthesis, antitumor, and apoptosis-inducing activities of novel 5-arylidenethiazolidine-2,4-dione derivatives: Histone deacetylases inhibitory activity and molecular docking study

by Hamdi, Abdelrahman, Elhusseiny, Walaa M., Othman, Dina I.A., Haikal, Abdullah, Bakheit, Ahmed H., El-Azab, Adel S., Al-Agamy, Mohamed H.M., Abdel-Aziz, Alaa A.-M.
Published in European journal of medicinal chemistry (15.12.2022)

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Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study

by El-Azab, Adel S., Al-Omar, Mohamed A., Abdel-Aziz, Alaa A.-M., Abdel-Aziz, Naglaa I., El-Sayed, Magda A.-A., Aleisa, Abdulaziz M., Sayed-Ahmed, Mohamed M., Abdel-Hamide, Sami G.
Published in European journal of medicinal chemistry (01.09.2010)

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Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2

Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2

by Alkahtani, Hamad M., Abdalla, Ashraf N., Obaidullah, Ahmad J., Alanazi, Mohammed M., Almehizia, Abdulrahman A., Alanazi, Mashael G., Ahmed, Ahmed Y., Alwassil, Osama I., Darwish, Hany W., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S.
Published in Bioorganic chemistry (01.01.2020)

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Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds

Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds

by El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Ayyad, Rezk R., Ceruso, Mariangela, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (01.01.2016)

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Design, synthesis, antitumor, and VEGFR-2 inhibition activities of novel 4-anilino-2-vinyl-quinazolines: Molecular modeling studies

Design, synthesis, antitumor, and VEGFR-2 inhibition activities of novel 4-anilino-2-vinyl-quinazolines: Molecular modeling studies

by Hamdi, Abdelrahman, El-Shafey, Hamed W., Othman, Dina I.A., El-Azab, Adel S., AlSaif, Nawaf A., Abdel-Aziz, Alaa A.-M.
Published in Bioorganic chemistry (01.05.2022)

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Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors

Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors

by El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Bua, Sivia, Nocentini, Alessio, El-Gendy, Manal A., Mohamed, Menshawy A., Shawer, Taghreed Z., AlSaif, Nawaf A., Supuran, Claudiu T.
Published in Bioorganic chemistry (01.06.2019)

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Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds

Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds

by Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., Ceruso, Mariangela, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry letters (15.11.2014)

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New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment

New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment

by El-Azab, Adel S., Abdel-Aziz, Alaa A.-M., Bua, Silvia, Nocentini, Alessio, AlSaif, Nawaf A., Almehizia, Abdulrahman A., Alanazi, Mohammed M., Hefnawy, Mohamed M., Supuran, Claudiu T.
Published in European journal of medicinal chemistry (01.11.2019)

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