A Phase 1 First‐in‐Human Single‐Ascending‐Dose Trial With ESB1609, a Selective Agonist to the Sphingosine‐1‐Phosphate Receptor 5
France, Nicholas P., Rubino, Christopher, Safir, M. Courtney, Maurer, Mari, Duong, Tram, Singamsetty, Deepika, Abd‐Elaziz, Khalid, Chou, Thomas, Sankaranarayanan, Sethu, Ettema, Marieke, Cosford, Rebecca, Dogterom, Peter, Liu, Enchi, Barlow, Carrolee
Published in Clinical pharmacology in drug development (01.06.2023)
Published in Clinical pharmacology in drug development (01.06.2023)
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Validation of a method for the determination of Aderamastat (FP-025) in K2EDTA human plasma by LC-MS/MS
Abd-Elaziz, Khalid S., Cheng, Rex, Chen, Joe, Maarse, Hans, Lee, Yisheng, Yang, Wenjin, Chien, Benjamin, Diamant, Zuzana, Kosterink, Jos, Touw, Daniël J.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.09.2024)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.09.2024)
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Letter to the editor: indacaterol/glycopyrronium/mometasone furoate compared with salmeterol/fluticasone propionate in patients with asthma: a randomized controlled cross-over study
Watz, Henrik, Hohlfeld, Jens M, Singh, Dave, Beier, Jutta, Diamant, Zuzana, Liu, Jinming, Hua, Shucheng, Abd-Elaziz, Khalid, Pinot, Pascale, Jones, Ieuan, Tillmann, Hanns-Christian
Published in Respiratory research (15.04.2020)
Published in Respiratory research (15.04.2020)
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Oral follicle-stimulating hormone agonist tested in healthy young women of reproductive age failed to demonstrate effect on follicular development but affected thyroid function
Gerrits, Mireille G.F., Pharm.D, Kramer, Hester, Ph.D, Galta, Rachid el, Ph.D, van Beerendonk, Geertje, Ph.D, Hanssen, Rob, Ph.D, Abd-Elaziz, Khalid, M.D, Klipping, Christine, M.D., Ph.D, Duijkers, Ingrid, M.D., Ph.D, Stoch, S. Aubrey, M.D
Published in Fertility and sterility (01.04.2016)
Published in Fertility and sterility (01.04.2016)
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Pharmacokinetics and pharmacodynamics of PTC518, an oral huntingtin lowering splicing modifier: A first-in-human study
Gao, Lan, Bhattacharyya, Anuradha, Beers, Brian, Kaushik, Diksha, Bredlau, Amy-Lee, Kristensen, Allan, Abd-Elaziz, Khalid, Grant, Richard, Golden, Lee, Kong, Ronald
Published in British journal of clinical pharmacology (18.08.2024)
Published in British journal of clinical pharmacology (18.08.2024)
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A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials
Abd-Elaziz, Khalid, Duijkers, Ingrid, Stöckl, Lars, Dietrich, Bruno, Klipping, Christine, Eckert, Kelvin, Goletz, Steffen
Published in Human reproduction (Oxford) (01.08.2017)
Published in Human reproduction (Oxford) (01.08.2017)
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Relative bioavailability and food effect of the galectin-3 inhibitor selvigaltin (GB1211) administered as a tablet in healthy participants (GALBA-1)
Aslanis, Vassilios, Abd-Elaziz, Khalid, Slack, Robert J, Brinch, Anne, Gravelle, Lise, Morley, Wayne, Phung, De, Herman, Kimberly, Holyer, Ian, Poulsen, Karen Killerup, Dogterom, Peter, Tantawi, Susan, Zetterberg, Fredrik R, Jacoby, Brian, Schambye, Hans, Lindmark, Bertil
Published in Cancer chemotherapy and pharmacology (21.08.2024)
Published in Cancer chemotherapy and pharmacology (21.08.2024)
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Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action)
Wilkinson, Joanne, Abd-Elaziz, Khalid, den Daas, Izaak, Wemer, Johan, van Haastert, Michiel, Hodgkinson, Victoria, Foster, Michelle, Coyle, Cathal
Published in Drug development and industrial pharmacy (04.03.2019)
Published in Drug development and industrial pharmacy (04.03.2019)
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First-in-Man Safety, Tolerability, and Pharmacokinetics of a Novel and Highly Selective Inhibitor of Matrix Metalloproteinase-12, FP-025: Results from Two Randomized Studies in Healthy Subjects
Abd-Elaziz, Khalid, Voors-Pette, Christine, Wang, Kang-Ling, Pan, Sandy, Lee, Yisheng, Mao, John, Li, Yuhua, Chien, Benjamin, Lau, David, Diamant, Zuzana
Published in Clinical drug investigation (2021)
Published in Clinical drug investigation (2021)
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Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study
Bourdès, Valérie, Dogterom, Peter, Aleman, André, Parmantier, Pierre, Colas, Damien, Lemarchant, Sighild, Marie, Sébastien, Chou, Thomas, Abd-Elaziz, Khalid, Godfrin, Yann
Published in Neurology and therapy (01.09.2022)
Published in Neurology and therapy (01.09.2022)
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Safety and Tolerability of Lumbar Catheterization and Lumbar Puncture for Cerebrospinal Fluid Analysis in Clinical Neurology Drug Studies
P. France, Nicholas, Dogterom, Peter, Ettema, Marieke, Maurer, Mari, Sankaranarayanan, Sethu, Abd-Elaziz, Khalid, Aalders, Wytze, Voors Pette, Christine, Liu, Enchi, Barlow, Carolee
Published in Clinical research and trials (2023)
Published in Clinical research and trials (2023)
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O1‐12‐05: PHASE 1 STUDY IN HEALTHY VOLUNTEERS OF THE O‐GLCNACASE INHIBITOR ASN120290 AS A NOVEL THERAPY FOR PROGRESSIVE SUPRANUCLEAR PALSY AND RELATED TAUOPATHIES
Ryan, J. Michael, Quattropani, Anna, Abd-Elaziz, Khalid, Daas, Izaak, Schneider, Manfred, Ousson, Solenne, Neny, Maud, Sand, Astrid, Hantson, Jennifer, Permanne, Bruno, Wiessner, Christoph, Beher, Dirk
Published in Alzheimer's & dementia (01.07.2018)
Published in Alzheimer's & dementia (01.07.2018)
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Efficacy and safety of single- and repeated-selurampanel dosing for 2 weeks in patients with chronic subjective tinnitus: Results of a randomized, double-blind, placebo-controlled, cross-over, proof-of-concept phase IIa study
Kucher, Klaus, Johns, Donald, Wagner, Frank, Abd-Elaziz, Khalid, Derne, Caroline, Sverdlov, Oleksandr, Pfister, Christian U, Langguth, Berthold
Published in Progress in brain research (2021)
Published in Progress in brain research (2021)
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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Anti-Vwf Nanobody® ALX-0681 After Single and Multiple Subcutaneous Administrations to Healthy Volunteers
Abd-Elaziz, Khalid, Kamphuisen, Pieter W., Lyssens, Christophe, Reuvers, Mariska, den Daas, Izaak, Van Bockstaele, Femke, Vercruysse, Kristof, Ulrichts, Hans, Baumeister, Judith, Crabbe, Patricia, Compernolle, Veerle, Holz, Josefin-Beate
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Detection and biovar discrimination of Ureaplasma urealyticum colonization in preterm neonates under ventilation and correlation with bronchopulmonary dysplasia
Noha, Tharwat Abou El-khier, Khalid, Fathy Abd ELaziz Megahed, Mohamed, Awad Shokier
Published in African journal of microbiology research (02.07.2014)
Published in African journal of microbiology research (02.07.2014)
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