Discovery of N‑[4-[6-tert-Butyl-5-methoxy-8-(6-methoxy-2-oxo‑1H‑pyridin-3-yl)-3-quinolyl]phenyl]methanesulfonamide (RG7109), a Potent Inhibitor of the Hepatitis C Virus NS5B Polymerase
Talamas, Francisco X., Abbot, Sarah C., Anand, Shalini, Brameld, Ken A., Carter, David S., Chen, Jun, Davis, Dana, de Vicente, Javier, Fung, Amy D., Gong, Leyi, Harris, Seth F., Inbar, Petra, Labadie, Sharada S., Lee, Eun K., Lemoine, Remy, Le Pogam, Sophie, Leveque, Vincent, Li, Jim, McIntosh, Joel, Nájera, Isabel, Park, Jaehyeon, Railkar, Aruna, Rajyaguru, Sonal, Sangi, Michael, Schoenfeld, Ryan C., Staben, Leanna R., Tan, Yunchou, Taygerly, Joshua P., Villaseñor, Armando G., Weller, Paul E.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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SYNTHESIS OF HETEROARYL-FUSED PYRAZOLES AS P38 KINASE INHIBITORS
Abbot, Sarah C., Billedeau, Roland J., Dewdney, Nolan J., Gabriel, Tobias, Goldstein, David M., McCaleb, Kristen L., Soth, Michael, Trejo-Martin, Teresa Alejandra, Zecic, Hasim
Published in Heterocycles (01.11.2009)
Published in Heterocycles (01.11.2009)
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Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-proteinase. Part 2: Solid-phase optimization of side chains
DANKWARDT, Sharon M, ABBOT, Sarah C, BROKA, Chris A, MARTIN, Robert L, CHAN, Christine S, SPRINGMAN, Eric B, VAN WART, Harold E, WALKER, Keith A. M
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
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Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase
Dankwardt, Sharon M, Billedeau, Roland J, Lawley, Linda K, Abbot, Sarah C, Martin, Robert L, Chan, Christine S, Van Wart, Harold E, Walker, Keith A.M
Published in Bioorganic & medicinal chemistry letters (20.11.2000)
Published in Bioorganic & medicinal chemistry letters (20.11.2000)
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Laser Flash Photolysis Study of Alkylhalocarbenes Generated from Non-Nitrogenous Precursors
Robert, Marc, Likhotvorik, Igor, Platz, Matthew S, Abbot, Sarah C, Johnson, Richard
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (26.02.1998)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (26.02.1998)
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3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead
Soth, Michael, Abbot, Sarah, Abubakari, Allassan, Arora, Nidhi, Arzeno, Humberto, Billedeau, Roland, Dewdney, Nolan, Durkin, Kieran, Frauchiger, Sandra, Ghate, Manjiri, Goldstein, David M., Hill, Ronald J., Kuglstatter, Andreas, Li, Fujun, Loe, Brad, McCaleb, Kristen, McIntosh, Joel, Papp, Eva, Park, Jaehyeon, Stahl, Martin, Sung, Man-Ling, Suttman, Rebecca, Swinney, David C., Weller, Paul, Wong, Brian, Zecic, Hasim, Gabriel, Tobias
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Discovery of a novel series of 4-quinolone JNK inhibitors
Gong, Leyi, Tan, Yun-Chou, Boice, Genevieve, Abbot, Sarah, McCaleb, Kristen, Iyer, Pravin, Zuo, Fengrong, Porto, Joseph Dal, Wong, Brian, Jin, Sue, Chang, Alice, Tran, Patricia, Hsieh, Gary, Niu, Linghao, Shao, Ada, Reuter, Deborah, Lukacs, Christine M., Ursula Kammlott, R., Kuglstatter, Andreas, Goldstein, David
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
Published in Bioorganic & medicinal chemistry letters (15.12.2012)
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DIHYDROQUINONE AND DIHYDRONAPHTHRIDINE INHIBITORS OF JNK
ABBOT, SARAH C, GOLDSTEIN, DAVID MICHAEL, HOGG, JOAN HEATHER, MCCALEB, KRISTEN LYNN, GONG, LEYI, BUETTELMANN, BERND, IYER, PRAVIN, BOICE, GENEVIEVE N, TAN, YUNOU
Year of Publication 12.01.2016
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Year of Publication 12.01.2016
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Heterocyclic antiviral compounds
Abbot, Sarah C, Lui, Alfred Sui-Ting, Li, Jim, Talamas, Francisco Xavier
Year of Publication 01.05.2012
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Year of Publication 01.05.2012
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HETEROCYCLIC ANTIVIRAL COMPOUNDS
ABBOT, SARAH C, TALAMAS, FRANCISCO XAVIER, LUI, ALFRED SUI-TING, LI, JIM
Year of Publication 11.01.2012
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Year of Publication 11.01.2012
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HETEROCYCLIC ANTIVIRAL COMPOUNDS
ABBOT, SARAH C, TALAMAS, FRANCISCO XAVIER, LUI, ALFRED SUI-TING, LI, JIM
Year of Publication 28.10.2011
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Year of Publication 28.10.2011
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Heterocyclic antiviral compounds
ABBOT, SARAH C, TALAMAS, FRANCISCO XAVIER, LUI, ALFRED SUI-TING, LI, JIM
Year of Publication 01.09.2011
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Year of Publication 01.09.2011
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HETEROCYCLIC ANTIVIRAL COMPOUNDS
ABBOT, SARAH C, TALAMAS, FRANCISCO XAVIER, LUI, ALFRED SUI-TING, LI, JIM
Year of Publication 10.09.2010
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Year of Publication 10.09.2010
Patent
HETEROCYCLIC ANTIVIRAL COMPOUNDS
ABBOT, SARAH C, TALAMAS, FRANCISCO XAVIER, LUI, ALFRED SUI-TING, LI, JIM
Year of Publication 10.09.2010
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Year of Publication 10.09.2010
Patent