CATH: increased structural coverage of functional space
Sillitoe, Ian, Bordin, Nicola, Dawson, Natalie, Waman, Vaishali P, Ashford, Paul, Scholes, Harry M, Pang, Camilla S M, Woodridge, Laurel, Rauer, Clemens, Sen, Neeladri, Abbasian, Mahnaz, Le Cornu, Sean, Lam, Su Datt, Berka, Karel, Varekova, Ivana Hutařová, Svobodova, Radka, Lees, Jon, Orengo, Christine A
Published in Nucleic acids research (08.01.2021)
Published in Nucleic acids research (08.01.2021)
Get full text
Journal Article
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics
Waman, Vaishali P, Ashford, Paul, Lam, Su Datt, Sen, Neeladri, Abbasian, Mahnaz, Woodridge, Laurel, Goldtzvik, Yonathan, Bordin, Nicola, Wu, Jiaxin, Sillitoe, Ian, Orengo, Christine A
Published in Scientific reports (20.06.2024)
Published in Scientific reports (20.06.2024)
Get full text
Journal Article
Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Roddie, Claire, Dias, Juliana, O'Reilly, Maeve A, Abbasian, Mahnaz, Cadinanos-Garai, Amaia, Vispute, Ketki, Bosshard-Carter, Leticia, Mitsikakou, Marina, Mehra, Vedika, Roddy, Harriet, Hartley, John A, Spanswick, Victoria, Lowe, Helen, Popova, Bilyana, Clifton-Hadley, Laura, Wheeler, Graham, Olejnik, Joanna, Bloor, Adrian, Irvine, David, Wood, Leigh, Marzolini, Maria A V, Domning, Sabine, Farzaneh, Farzin, Lowdell, Mark W, Linch, David C, Pule, Martin A, Peggs, Karl S
Published in Journal of clinical oncology (20.10.2021)
Published in Journal of clinical oncology (20.10.2021)
Get full text
Journal Article
Safety and Efficacy of AUTO1, a Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)
Roddie, Claire, Dias, Juliana, O'Reilly, Maeve A, Cadinanos Garai, Amaia, Green, Louisa, Abbasian, Mahnaz, Mitsikakou, Marina, Vaughan, Mhairi, Meyer Cantinho Pereira, Vitoria, Marzolini, Maria A V, Wood, Leigh, Olejnik, Joanna, Ngai, Yenting, Popova, Bilyana, Wilson, William, Spanswick, Victoria, Lowe, Helen, Ensell, Leah, Hartley, John A., Farzaneh, Farzin, Lowdell, Mark W., Linch, David C., Pule, Martin, Peggs, Karl S
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
ALLCAR19: Updated Data Using AUTO1, a Novel Fast-Off Rate CD19 CAR in Relapsed/Refractory B-Cell Acute Lymphoblastic Leukaemia and Other B-Cell Malignancies
Roddie, Claire, O'Reilly, Maeve A, Marzolini, Maria A V, Wood, Leigh, Dias, Juliana, Cadinanos Garai, Amaia, Bosshard, Leticia, Abbasian, Mahnaz, Lowdell, Mark W., Wheeler, Graham, Olejnik, Joanna, Popova, Bilyana, Clifton-Hadley, Laura, Pathak, Yashma, Spanswick, Victoria, Lowe, Helen, Hartley, John A., Syed, Farhatullah, Qasim, Waseem, Farzaneh, Farzin, Linch, David C., Pule, Martin, Peggs, Karl S
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article
RNA-seq of newly diagnosed patients in the PADIMAC study leads to a bortezomib/lenalidomide decision signature
Chapman, Michael A., Sive, Jonathan, Ambrose, John, Roddie, Claire, Counsell, Nicholas, Lach, Anna, Abbasian, Mahnaz, Popat, Rakesh, Cavenagh, Jamie D., Oakervee, Heather, Streetly, Matthew J., Schey, Stephen, Koh, Mickey, Willis, Fenella, Virchis, Andres E., Crowe, Josephine, Quinn, Michael F., Cook, Gordon, Crawley, Charles R., Pratt, Guy, Cook, Mark, Braganza, Nivette, Adedayo, Toyin, Smith, Paul, Clifton-Hadley, Laura, Owen, Roger G., Sonneveld, Pieter, Keats, Jonathan J., Herrero, Javier, Yong, Kwee
Published in Blood (15.11.2018)
Published in Blood (15.11.2018)
Get full text
Journal Article
Automated Manufacture of Matched Donor-Derived Allogeneic CD19 CAR T-Cells for Relapsed/Refractory B-ALL Following Allogeneic Stem Cell Transplantation: Toxicity, Efficacy and the Important Role of Lymphodepletion
Roddie, Claire, O'Reilly, Maeve A, Marzolini, Maria A V, Wood, Leigh, Dias Alves Pinto, Juliana, Abbasian, Mahnaz, Vispute, Ketki, Bosshard, Leticia, Lowdell, Mark W., Wheeler, Graham, Day, Alex, Popova, Bilyana, Champion, Kim, Pathak, Yashma, Gali, Alexia, Mahmoud, Nasir, Spanswick, Victoria, Lowe, Helen, Hartley, John A., Farzaneh, Farzin, Nickolay, Lauren, Syed, Fahetullah, Qasim, Waseem, Linch, David C., Pule, Martin, Peggs, Karl S
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
AUTO1, a Novel Fast Off CD19CAR Delivers Durable Remissions and Prolonged CAR T Cell Persistence with Low CRS or Neurotoxicity in Adult ALL
Roddie, Claire, O'Reilly, Maeve A, Marzolini, Maria A V, Wood, Leigh, Dias Alves Pinto, Juliana, Abbasian, Mahnaz, Vispute, Ketki, Lowdell, Mark W., Wheeler, Graham, Olejnik, Joanna, Popova, Bilyana, Champion, Kim, Gali, Alexia, Pathak, Yashma, Spanswick, Victoria, Lowe, Helen, Hartley, John A., Farzaneh, Farzin, Linch, David C., Pule, Martin, Peggs, Karl S
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
Mbd3 Promotes Reprogramming of Primary Human Fibroblasts
Jaffer, Sajjida, Goh, Pollyanna, Abbasian, Mahnaz, Nathwani, Amit C
Published in International journal of stem cells (30.11.2018)
Published in International journal of stem cells (30.11.2018)
Get full text
Journal Article
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics
Waman, Vaishali P, Ashford, Paul, Lam, Su Datt, Sen, Neeladri, Abbasian, Mahnaz, Woodridge, Laurel, Goldtzvik, Yonathan, Bordin, Nicola, Wu, Jiaxin, Sillitoe, Ian, Orengo, Christine
Published in bioRxiv (08.11.2023)
Published in bioRxiv (08.11.2023)
Get full text
Paper
SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals
Lam, Su Datt, Bordin, Nicola, Waman, Vaishali P, Scholes, Harry M, Ashford, Paul, Sen, Neeladri, Lucy Van Dorp, Rauer, Clemens, Dawson, Natalie L, Pang, Camilla Sm, Abbasian, Mahnaz, Sillitoe, Ian, Edwards, Sarah Jl, Fraternali, Franca, Lees, Jonathan G, Santini, Joanne M, Orengo, Christine A
Published in bioRxiv (12.06.2020)
Published in bioRxiv (12.06.2020)
Get full text
Paper