4-Substituted-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine Derivatives: Design, Synthesis, Antitumor and EGFR Tyrosine Kinase Inhibitory Activity
Abbas, Safinaz E.-S., Aly, Enayat I., Awadallah, Fadi M., Mahmoud, Walaa R.
Published in Chemical biology & drug design (01.05.2015)
Published in Chemical biology & drug design (01.05.2015)
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Design and synthesis of some new 6-bromo-2-(pyridin-3-yl)-4-substituted quinazolines as multi tyrosine kinase inhibitors
Farouk, Ahmed K.B.A.W., Abdelrasheed Allam, Heba, Rashwan, Essam, George, Riham F., Abbas, Safinaz E-S.
Published in Bioorganic chemistry (01.11.2022)
Published in Bioorganic chemistry (01.11.2022)
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Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors
Oudah, Khulood H., Mahmoud, Walaa R., Awadallah, Fadi M., Taher, Azza T., Abbas, Safinaz E.-S, Allam, Heba Abdelrasheed, Vullo, Daniela, Supuran, Claudiu T.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Design and synthesis of some new benzoylthioureido phenyl derivatives targeting carbonic anhydrase enzymes
Najm, Mazin A. A., Mahmoud, Walaa R., Taher, Azza T., Abbas, Safinaz E-S., Awadallah, Fadi M., Allam, Heba Abdelrasheed, Vullo, Daniela, Supuran, Claudiu T.
Published in Journal of enzyme inhibition and medicinal chemistry (31.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (31.12.2022)
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Design, synthesis, and molecular docking of novel indole scaffold‐based VEGFR‐2 inhibitors as targeted anticancer agents
Roaiah, Hanaa M., Ghannam, Iman A. Y., Ali, Islam H., El Kerdawy, Ahmed M., Ali, Mamdouh M., Abbas, Safinaz E‐S., El‐Nakkady, Sally S.
Published in Archiv der Pharmazie (Weinheim) (01.02.2018)
Published in Archiv der Pharmazie (Weinheim) (01.02.2018)
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Design, Synthesis, and Biological Evaluation of Some Cyclohepta[b]Thiophene and Substituted Pentahydrocycloheptathieno[2,3‐d]Pyrimidine Derivatives
Elmongy, Elshaymaa I., Khedr, Mohammed A., Taleb, Nageh A., Awad, Hanem M., Abbas, Safinaz E.‐S.
Published in Journal of heterocyclic chemistry (01.03.2017)
Published in Journal of heterocyclic chemistry (01.03.2017)
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Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G1 cell-cycle arrest
Fares, Mohamed, Abou-Seri, Sahar Mahmoud, Abdel-Aziz, Hatem A., Abbas, Safinaz E.-S., Youssef, Mohieldin Magdy, Eladwy, Radwa Ahmed
Published in European journal of medicinal chemistry (18.08.2014)
Published in European journal of medicinal chemistry (18.08.2014)
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Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors
George, Riham F., Samir, Eman M., Abdelhamed, Mennatullah N., Abdel-Aziz, Hatem A., Abbas, Safinaz E-S.
Published in Bioorganic chemistry (01.03.2019)
Published in Bioorganic chemistry (01.03.2019)
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New 6-nitro-4-substituted quinazoline derivatives targeting epidermal growth factor receptor: design, synthesis and in vitro anticancer studies
Farag, Ayman B, Othman, Aya H, El-Ashrey, Mohamed K, Abbas, Safinaz E-S, Elwaie, Tamer A
Published in Future medicinal chemistry (01.10.2024)
Published in Future medicinal chemistry (01.10.2024)
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Journal Article
Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G(1) cell-cycle arrest
Fares, Mohamed, Abou-Seri, Sahar Mahmoud, Abdel-Aziz, Hatem A., Abbas, Safinaz E. -S., Youssef, Mohieldin Magdy, Eladwy, Radwa Ahmed
Published in European journal of medicinal chemistry (18.08.2014)
Published in European journal of medicinal chemistry (18.08.2014)
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Some 2-(4-bromophenoxymethyl)-6-iodo-3-substituted quinazolin-4(3H)ones: Synthesis, cytotoxic activity, EGFR inhibition and molecular docking
Abbas, Safinaz E-S., Abdel-Gawad, Nagwa M., George, Riham F., Elyazid, Mohamed G. Abu, Zaater, Marwa A., El-Ashrey, Mohamed K.
Published in Journal of molecular structure (05.12.2022)
Published in Journal of molecular structure (05.12.2022)
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Journal Article
Synthesis and anticancer activity of some pyrido[2,3- d ]pyrimidine derivatives as apoptosis inducers and cyclin-dependent kinase inhibitors
Abbas, Safinaz E-S, George, Riham F, Samir, Eman M, Aref, Mostafa Ma, Abdel-Aziz, Hatem A
Published in Future medicinal chemistry (01.09.2019)
Published in Future medicinal chemistry (01.09.2019)
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Journal Article
4‐Substituted‐1‐phenyl‐1 H ‐pyrazolo[3,4‐ d ]pyrimidine Derivatives: Design, Synthesis, Antitumor and EGFR Tyrosine Kinase Inhibitory Activity
Abbas, Safinaz E.‐S., Aly, Enayat I., Awadallah, Fadi M., Mahmoud, Walaa R.
Published in Chemical biology & drug design (01.05.2015)
Published in Chemical biology & drug design (01.05.2015)
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Journal Article