A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia
Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.
Published in Nature Medicine (01.06.2022)
Published in Nature Medicine (01.06.2022)
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Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Chu, Yanshuo, Dai, Enyu, Li, Yating, Han, Guangchun, Pei, Guangsheng, Ingram, Davis R., Thakkar, Krupa, Qin, Jiang-Jiang, Dang, Minghao, Le, Xiuning, Hu, Can, Deng, Qing, Sinjab, Ansam, Gupta, Pravesh, Wang, Ruiping, Hao, Dapeng, Peng, Fuduan, Yan, Xinmiao, Liu, Yunhe, Song, Shumei, Zhang, Shaojun, Heymach, John V., Reuben, Alexandre, Elamin, Yasir Y., Pizzi, Melissa P., Lu, Yang, Lazcano, Rossana, Hu, Jian, Li, Mingyao, Curran, Michael, Futreal, Andrew, Maitra, Anirban, Jazaeri, Amir A., Ajani, Jaffer A., Swanton, Charles, Cheng, Xiang-Dong, Abbas, Hussein A., Gillison, Maura, Bhat, Krishna, Lazar, Alexander J., Green, Michael, Litchfield, Kevin, Kadara, Humam, Yee, Cassian, Wang, Linghua
Published in Nature medicine (01.06.2023)
Published in Nature medicine (01.06.2023)
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Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia
Rutella, Sergio, Vadakekolathu, Jayakumar, Mazziotta, Francesco, Reeder, Stephen, Yau, Tung-On, Mukhopadhyay, Rupkatha, Dickins, Benjamin, Altmann, Heidi, Kramer, Michael, Knaus, Hanna A, Blazar, Bruce R, Radojcic, Vedran, Zeidner, Joshua F, Arruda, Andrea, Wang, Bofei, Abbas, Hussein A, Minden, Mark D, Tasian, Sarah K, Bornhäuser, Martin, Gojo, Ivana, Luznik, Leo
Published in The Journal of clinical investigation (01.11.2022)
Published in The Journal of clinical investigation (01.11.2022)
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Outcomes and genetic dynamics of acute myeloid leukemia at first relapse
Bataller, Alex, Kantarjian, Hagop, Bazinet, Alexandre, Kadia, Tapan, Daver, Naval, DiNardo, Courtney D, Borthakur, Gautam, Loghavi, Sanam, Patel, Keyur, Tang, Guilin, Sasaki, Koji, Short, Nicholas J, Yilmaz, Musa, Issa, Ghayas C, Alvarado, Yesid, Montalban-Bravo, Guillermo, Maiti, Abhishek, Abbas, Hussein A, Takahashi, Koichi, Pierce, Sherry, Jabbour, Elias, Garcia-Manero, Guillermo, Ravandi, Farhad
Published in Haematologica (Roma) (02.05.2024)
Published in Haematologica (Roma) (02.05.2024)
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Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies
Wang, Bofei, Reville, Patrick K., Yassouf, Mhd Yousuf, Jelloul, Fatima Z., Ly, Christopher, Desai, Poonam N., Wang, Zhe, Borges, Pamella, Veletic, Ivo, Dasdemir, Enes, Burks, Jared K., Tang, Guilin, Guo, Shengnan, Garza, Araceli Isabella, Nasnas, Cedric, Vaughn, Nicole R., Baran, Natalia, Deng, Qing, Matthews, Jairo, Gunaratne, Preethi H., Antunes, Dinler A., Ekmekcioglu, Suhendan, Sasaki, Koji, Garcia, Miriam B., Cuglievan, Branko, Hao, Dapeng, Daver, Naval, Green, Michael R., Konopleva, Marina, Futreal, Andrew, Post, Sean M., Abbas, Hussein A.
Published in Nature communications (28.02.2024)
Published in Nature communications (28.02.2024)
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Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment
Chomczyk, Monika, Gazzola, Luca, Dash, Shubhankar, Firmanty, Patryk, George, Binsah S, Mohanty, Vakul, Abbas, Hussein A, Baran, Natalia
Published in Frontiers in pharmacology (05.08.2024)
Published in Frontiers in pharmacology (05.08.2024)
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Author Correction: ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer
Napoli, Marco, Wu, Sarah J., Gore, Bethanie L., Abbas, Hussein A., Lee, Kyubum, Checker, Rahul, Dhar, Shilpa, Rajapakshe, Kimal, Tan, Aik Choon, Lee, Min Gyu, Coarfa, Cristian, Flores, Elsa R.
Published in Nature communications (25.03.2022)
Published in Nature communications (25.03.2022)
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The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics
Tang, Ming, Abbas, Hussein A., Negrao, Marcelo V., Ramineni, Maheshwari, Hu, Xin, Hubert, Shawna Marie, Fujimoto, Junya, Reuben, Alexandre, Varghese, Susan, Zhang, Jianhua, Li, Jun, Chow, Chi-Wan, Mao, Xizeng, Song, Xingzhi, Lee, Won-Chul, Wu, Jia, Little, Latasha, Gumbs, Curtis, Behrens, Carmen, Moran, Cesar, Weissferdt, Annikka, Lee, J. Jack, Sepesi, Boris, Swisher, Stephen, Cheng, Chao, Kurie, Jonathan, Gibbons, Don, Heymach, John V., Wistuba, Ignacio I., Futreal, P. Andrew, Kalhor, Neda, Zhang, Jianjun
Published in Nature communications (06.12.2021)
Published in Nature communications (06.12.2021)
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Mdm2 Is Required for Survival of Hematopoietic Stem Cells/Progenitors via Dampening of ROS-Induced p53 Activity
Abbas, Hussein A., Maccio, Daniela R., Coskun, Suleyman, Jackson, James G., Hazen, Amy L., Sills, Tiffany M., You, M. James, Hirschi, Karen K., Lozano, Guillermina
Published in Cell stem cell (05.11.2010)
Published in Cell stem cell (05.11.2010)
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The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity
Pant, Vinod, Xiong, Shunbin, Jackson, James G, Post, Sean M, Abbas, Hussein A, Quintás-Cardama, Alfonso, Hamir, Amirali N, Lozano, Guillermina
Published in Genes & development (01.09.2013)
Published in Genes & development (01.09.2013)
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Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes
Abbas, Hussein A, Reville, Patrick K, Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C, Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo
Published in Frontiers in immunology (12.04.2021)
Published in Frontiers in immunology (12.04.2021)
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Paired single-B-cell transcriptomics and receptor sequencing reveal activation states and clonal signatures that characterize B cells in acute myeloid leukemia
Guo, Shengnan, Mohan, Gopi S, Wang, Bofei, Li, Tianhao, Daver, Naval, Zhao, Yuting, Reville, Patrick K, Hao, Dapeng, Abbas, Hussein A
Published in Journal for immunotherapy of cancer (28.02.2024)
Published in Journal for immunotherapy of cancer (28.02.2024)
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A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative analysis
Senapati, Jayastu, Muftuoglu, Muharrem, Ishizawa, Jo, Abbas, Hussein A., Loghavi, Sanam, Borthakur, Gautam, Yilmaz, Musa, Issa, Ghayas C., Dara, Samuel I., Basyal, Mahesh, Li, Li, Naqvi, Kiran, Pourebrahim, Rasoul, Jabbour, Elias J., Kornblau, Steven M., Short, Nicholas J., Pemmaraju, Naveen, Garcia-Manero, Guillermo, Ravandi, Farhad, Khoury, Joseph, Daver, Naval, Kantarjian, Hagop M., Andreeff, Michael, DiNardo, Courtney D.
Published in Blood cancer journal (New York) (29.06.2023)
Published in Blood cancer journal (New York) (29.06.2023)
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Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance
Fan, Huihui, Wang, Feng, Zeng, Andy, Murison, Alex, Tomczak, Katarzyna, Hao, Dapeng, Jelloul, Fatima Zahra, Wang, Bofei, Barrodia, Praveen, Liang, Shaoheng, Chen, Ken, Wang, Linghua, Zhao, Zhongming, Rai, Kunal, Jain, Abhinav K., Dick, John, Daver, Naval, Futreal, Andy, Abbas, Hussein A.
Published in Communications biology (21.07.2023)
Published in Communications biology (21.07.2023)
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Nontuberculosis mycobacteria (NTM) infections in patients with leukemia: a single center case series
Marvin-Peek, Jennifer, Sasaki, Koji, Kontoyiannis, Dimitrios P, Adachi, Javier, Ohanian, Maro, Takahashi, Koichi, Issa, Ghayas C, Kornblau, Steven, Abbas, Hussein A
Published in Frontiers in medicine (01.08.2024)
Published in Frontiers in medicine (01.08.2024)
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Novel Cancer Immunotherapies and Antitumor Immunity
Zhao, Lei, Zhang, Jianjun, Xu, Liang, Abbas, Hussein A.
Published in Journal of Immunology Research (2019)
Published in Journal of Immunology Research (2019)
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The ups and downs of p53 regulation in hematopoietic stem cells
Abbas, Hussein A., Pant, Vinod, Lozano, Guillermina
Published in Cell cycle (Georgetown, Tex.) (01.10.2011)
Published in Cell cycle (Georgetown, Tex.) (01.10.2011)
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Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes
Abbas, Hussein A, Mohanty, Vakul, Wang, Ruiping, Huang, Yuefan, Liang, Shaoheng, Wang, Feng, Zhang, Jianhua, Qiu, Yihua, Hu, Chenyue W, Qutub, Amina A, Dail, Monique, Bolen, Christopher R, Daver, Naval, Konopleva, Marina, Futreal, Andrew, Chen, Ken, Wang, Linghua, Kornblau, Steven M
Published in Frontiers in oncology (04.08.2021)
Published in Frontiers in oncology (04.08.2021)
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