Search Results - "Abadi, Ashraf H." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease

by Hafez, Donia E., Dubiel, Mariam, La Spada, Gabriella, Catto, Marco, Reiner-Link, David, Syu, Yu-Ting, Abdel-Halim, Mohammad, Hwang, Tsong-Long, Stark, Holger, Abadi, Ashraf H.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)

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Advancements in Phosphodiesterase 5 Inhibitors: Unveiling Present and Future Perspectives

Advancements in Phosphodiesterase 5 Inhibitors: Unveiling Present and Future Perspectives

by ElHady, Ahmed K, El-Gamil, Dalia S, Abdel-Halim, Mohammad, Abadi, Ashraf H
Published in Pharmaceuticals (Basel, Switzerland) (01.09.2023)

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Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer

Novel 9-Benzylaminoacridine Derivatives as Dual Inhibitors of Phosphodiesterase 5 and Topoisomerase II for the Treatment of Colon Cancer

by Ammar, Lina, Lin, Hung-Yu, Shih, Shou-Ping, Tsai, Tsen-Ni, Syu, Yu-Ting, Abdel-Halim, Mohammad, Hwang, Tsong-Long, Abadi, Ashraf H
Published in Molecules (Basel, Switzerland) (14.01.2023)

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Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways

Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways

by Abdel-Halim, Mohammad, El-Gamil, Dalia S, Hammam, Mennatallah A, El-Shazly, Mohamed, Wang, Yi-Hsuan, Kung, Po-Hsiung, Chen, Yu-Cheng, Korinek, Michal, Abadi, Ashraf H, Engel, Matthias, Hwang, Tsong-Long
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2024)

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5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency

5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency

by ElHady, Ahmed K, El-Gamil, Dalia S, Chen, Po-Jen, Hwang, Tsong-Long, Abadi, Ashraf H, Abdel-Halim, Mohammad, Engel, Matthias
Published in Molecules (Basel, Switzerland) (13.02.2021)

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Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs

Manipulating Estrogenic/Anti-Estrogenic Activity of Triphenylethylenes towards Development of Novel Anti-Neoplastic SERMs

by Elnakib, Heba E, Ramsis, Marian M, Albably, Nouran O, Vector, Merna A, Weigand, Jan J, Schwedtmann, Kai, Wober, Jannette, Zierau, Oliver, Vollmer, Günter, Abadi, Ashraf H, Ahmed, Nermin S
Published in International journal of molecular sciences (22.11.2021)

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Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

by Tinsley, Heather N, Gary, Bernard D, Keeton, Adam B, Zhang, Wei, Abadi, Ashraf H, Reynolds, Robert C, Piazza, Gary A
Published in Molecular cancer therapeutics (01.12.2009)

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An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

by Harms, Mirja, Habib, Monica M.W., Nemska, Simona, Nicolò, Antonella, Gilg, Andrea, Preising, Nico, Sokkar, Pandian, Carmignani, Sara, Raasholm, Martina, Weidinger, Gilbert, Kizilsavas, Gönül, Wagner, Manfred, Ständker, Ludger, Abadi, Ashraf H., Jumaa, Hassan, Kirchhoff, Frank, Frossard, Nelly, Sanchez-Garcia, Elsa, Münch, Jan
Published in Acta pharmaceutica Sinica. B (01.09.2021)

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Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors

Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors

by Abadi, Ashraf H., Ibrahim, Tamer M., Abouzid, Khaled M., Lehmann, Jochen, Tinsley, Heather N., Gary, Bernard D., Piazza, Gary A.
Published in Bioorganic & medicinal chemistry (15.08.2009)

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Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors

Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors

by Darwish, Sarah S., Chen, Po-Jen, Hamed, Mostafa M., Wagdy, Reem A., Chen, Shun-Hua, Abadi, Ashraf H., Abdel-Halim, Mohammad, Hwang, Tsong-Long, Engel, Matthias
Published in Pharmaceuticals (Basel, Switzerland) (22.06.2022)

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Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors

Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors

by Hamdy, Jehad, Emadeldin, Nouran, Hamed, Mostafa M, Frakolaki, Efseveia, Katsamakas, Sotirios, Vassilaki, Niki, Zoidis, Grigoris, Hirsch, Anna K H, Abdel-Halim, Mohammad, Abadi, Ashraf H
Published in Pharmaceuticals (Basel, Switzerland) (20.05.2022)

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Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors

Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors

by Mousa, Mai H A, Ahmed, Nermin S, Schwedtmann, Kai, Frakolaki, Efseveia, Vassilaki, Niki, Zoidis, Grigoris, Weigand, Jan J, Abadi, Ashraf H
Published in Pharmaceuticals (Basel, Switzerland) (25.03.2021)

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Structure–Activity Relationships of Triphenylethylene Derivatives and Their Evaluation as Anticancer and Antiviral Agents

Structure–Activity Relationships of Triphenylethylene Derivatives and Their Evaluation as Anticancer and Antiviral Agents

by Ahmed, Nermin S., El-Nakib, Heba E., Ramsis, Marian M., Albably, Nouran O., Wober, Jannette, Weigand, Jan J., Schwedtmann, Kai, Zierau, Oliver, Abadi, Ashraf H.
Published in ACS omega (25.07.2023)

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Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach

Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach

by Abadi, Ashraf H., Abouel-Ella, Dalal A., Lehmann, Jochen, Tinsley, Heather N., Gary, Bernard D., Piazza, Gary A., Abdel-Fattah, Mohammed A.O.
Published in European journal of medicinal chemistry (01.01.2010)

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Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents

Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents

by Habib, Monica M. W., Abdelfattah, Mohamed A. O., Abadi, Ashraf H.
Published in Archiv der Pharmazie (Weinheim) (01.12.2015)

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Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties

Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties

by Ghonim, Aya E., Ligresti, Alessia, Rabbito, Alessandro, Mahmoud, Ali Mokhtar, Di Marzo, Vincenzo, Osman, Noha A., Abadi, Ashraf H.
Published in European journal of medicinal chemistry (15.10.2019)

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Symmetric Anti-HCV Agents: Synthesis, Antiviral Properties, and Conformational Aspects of Core Scaffolds

Symmetric Anti-HCV Agents: Synthesis, Antiviral Properties, and Conformational Aspects of Core Scaffolds

by Leila, Alaa R. S, Mousa, Mai H. A, Frakolaki, Efseveia, Vassilaki, Niki, Bartenschlager, Ralf, Zoidis, Grigoris, Abdel-Halim, Mohammad, Abadi, Ashraf H
Published in ACS omega (31.07.2019)

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Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins

Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins

by ElHady, Ahmed K, Abdel-Halim, Mohammad, Abadi, Ashraf H, Engel, Matthias
Published in Journal of medicinal chemistry (13.07.2017)

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Four-component synthesis of 1,2-dihydropyridine derivatives and their evaluation as anticancer agents

Four-component synthesis of 1,2-dihydropyridine derivatives and their evaluation as anticancer agents

by Abdel-Fattah, Mohamed A O, El-Naggar, Mahmoud A M, Rashied, Rasha M H, Gary, Bernard D, Piazza, Gary A, Abadi, Ashraf H
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.05.2012)

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An overview of cdc2‐like kinase 1 (Clk1) inhibitors and their therapeutic indications

An overview of cdc2‐like kinase 1 (Clk1) inhibitors and their therapeutic indications

by ElHady, Ahmed K., El‐Gamil, Dalia S., Abadi, Ashraf H., Abdel‐Halim, Mohammad, Engel, Matthias
Published in Medicinal research reviews (01.03.2023)

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