Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations
Christmann, Markus, Boisseau, Catherine, Kitzinger, Rebekka, Berac, Christian, Allmann, Sebastian, Sommer, Tina, Aasland, Dorthe, Kaina, Bernd, Tomicic, Maja T
Published in Nucleic acids research (15.12.2016)
Published in Nucleic acids research (15.12.2016)
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Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage
Christmann, Markus, Tomicic, Maja T, Aasland, Dorthe, Berdelle, Nicole, Kaina, Bernd
Published in Nucleic acids research (01.10.2010)
Published in Nucleic acids research (01.10.2010)
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Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs
Tomicic, Maja T., Aasland, Dorthe, Nikolova, Teodora, Kaina, Bernd, Christmann, Markus
Published in Biochimica et biophysica acta (01.08.2013)
Published in Biochimica et biophysica acta (01.08.2013)
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Temozolomide Induces Senescence and Repression of DNA Repair Pathways in Glioblastoma Cells via Activation of ATR-CHK1, p21, and NF-κB
Aasland, Dorthe, Götzinger, Laura, Hauck, Laura, Berte, Nancy, Meyer, Jessica, Effenberger, Melanie, Schneider, Simon, Reuber, Emelie E, Roos, Wynand P, Tomicic, Maja T, Kaina, Bernd, Christmann, Markus
Published in Cancer research (Chicago, Ill.) (01.01.2019)
Published in Cancer research (Chicago, Ill.) (01.01.2019)
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Repair gene O 6 -methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation
Aasland, Dorthe, Reich, Thomas R, Tomicic, Maja T, Switzeny, Olivier J, Kaina, Bernd, Christmann, Markus
Published in Journal of neurochemistry (01.01.2018)
Published in Journal of neurochemistry (01.01.2018)
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Journal Article
Translesion polymerase η is upregulated by cancer therapeutics and confers anticancer drug resistance
Tomicic, Maja T, Aasland, Dorthe, Naumann, Steffen C, Meise, Ruth, Barckhausen, Christina, Kaina, Bernd, Christmann, Markus
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM
Tomicic, Maja T, Meise, Ruth, Aasland, Dorthe, Berte, Nancy, Kitzinger, Rebekka, Krämer, Oliver H, Kaina, Bernd, Christmann, Markus
Published in Oncotarget (20.10.2015)
Published in Oncotarget (20.10.2015)
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Journal Article
Repair gene O6‐methylguanine‐DNA methyltransferase is controlled by SP1 and up‐regulated by glucocorticoids, but not by temozolomide and radiation
Aasland, Dorthe, Reich, Thomas R., Tomicic, Maja T., Switzeny, Olivier J., Kaina, Bernd, Christmann, Markus
Published in Journal of neurochemistry (01.01.2018)
Published in Journal of neurochemistry (01.01.2018)
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Journal Article
Receptor Recognition Sites of Cytokines Are Organized as Exchangeable Modules
Kallen, Karl-Josef, Grötzinger, Joachim, Lelièvre, Eric, Vollmer, Petra, Aasland, Dorthe, Renné, Christoph, Müllberg, Jürgen, zum Büschenfelde, Karl-Hermann Meyer, Gascan, Hugues, Rose-John, Stefan
Published in The Journal of biological chemistry (23.04.1999)
Published in The Journal of biological chemistry (23.04.1999)
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The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity
Tomaszowski, Karl-Heinz, Aasland, Dorthe, Margison, Geoffrey P., Williams, Emma, Pinder, Sarah I., Modesti, Mauro, Fuchs, Robert P., Kaina, Bernd
Published in DNA repair (01.04.2015)
Published in DNA repair (01.04.2015)
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c-Fos/AP-1 dependent regulation of the three prime exonuclease 1 (TREX1) by genotoxic stress
Christmann, Markus, Tomicic, Maja, Aasland, Dorthe, Schulz, Jana, Berdelle, Nicole, Reischmann, Patricia, Birkner, Ruth, Rasenberger, Birgit, Kaina, Bernd
Published in Toxicology letters (13.09.2009)
Published in Toxicology letters (13.09.2009)
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Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6
Kallen, K J, Grötzinger, J, Lelièvre, E, Vollmer, P, Aasland, D, Renné, C, Müllberg, J, Myer zum Büschenfelde, K H, Gascan, H, Rose-John, S
Published in The Journal of biological chemistry (23.04.1999)
Published in The Journal of biological chemistry (23.04.1999)
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Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
Althoff, K, Müllberg, J, Aasland, D, Voltz, N, Kallen, K, Grötzinger, J, Rose-John, S
Published in Biochemical journal (01.02.2001)
Published in Biochemical journal (01.02.2001)
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The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex
Aasland, Dorthe, Oppmann, Birgit, Grötzinger, Joachim, Rose-John, Stefan, Kallen, Karl-Josef
Published in Journal of molecular biology (25.01.2002)
Published in Journal of molecular biology (25.01.2002)
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The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex 1 1Edited by M. Yaniv
Aasland, Dorthe, Oppmann, Birgit, Grötzinger, Joachim, Rose-John, Stefan, Kallen, Karl-Josef
Published in Journal of molecular biology (01.01.2002)
Published in Journal of molecular biology (01.01.2002)
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Recognition sequences and structural elements contribute to shedding susceptibility of membrane proteins
ALTHOFF, Katja, MÜLLBERG, Jürgen, AASLAND, Dorthe, VOLTZ, Nicole, KALLEN, Karl-Josef, GRÖTZINGER, Joachim, ROSE-JOHN, Stefan
Published in Biochemical journal (01.02.2001)
Published in Biochemical journal (01.02.2001)
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