Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model
Braham, Maaike V. J., Minnema, Monique C., Aarts, Tineke, Sebestyen, Zsolt, Straetemans, Trudy, Vyborova, Anna, Kuball, Jurgen, Öner, F. Cumhur, Robin, Catherine, Alblas, Jacqueline
Published in Oncoimmunology (03.06.2018)
Published in Oncoimmunology (03.06.2018)
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Evaluating in vivo efficacy: toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells
Johanna, Inez, Straetemans, Trudy, Heijhuurs, Sabine, Aarts-Riemens, Tineke, Norell, Haakan, Bongiovanni, Laura, de Bruin, Alain, Sebestyen, Zsolt, Kuball, Jürgen
Published in Journal for immunotherapy of cancer (12.03.2019)
Published in Journal for immunotherapy of cancer (12.03.2019)
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Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance
de Haart, Sanne J, Holthof, Lisa, Noort, Willy A, Minnema, Monique C, Emmelot, Maarten E, Aarts-Riemens, Tineke, Doshi, Parul, Sasser, Kate, Yuan, Huipin, de Bruijn, Joost, Martens, Anton C M, van de Donk, Niels W C J, Lokhorst, Henk M, Groen, Richard W J, Mutis, Tuna
Published in Haematologica (Roma) (01.08.2016)
Published in Haematologica (Roma) (01.08.2016)
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Characterization and modulation of anti-αβTCR antibodies and their respective binding sites at the βTCR chain to enrich engineered T cells
Kierkels, Guido J.J., van Diest, Eline, Hernández-López, Patricia, Scheper, Wouter, de Bruin, Anja C.M., Frijlink, Elselien, Aarts-Riemens, Tineke, van Dooremalen, Sanne F.J., Beringer, Dennis X., Oostvogels, Rimke, Kramer, Lovro, Straetemans, Trudy, Uckert, Wolfgang, Sebestyén, Zsolt, Kuball, Jürgen
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Published in Molecular therapy. Methods & clinical development (10.09.2021)
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Human Regulatory T Cells Control Xenogeneic Graft-versus-Host Disease Induced by Autologous T Cells in RAG2−/−γc−/− Immunodeficient Mice
Mutis, Tuna, van Rijn, Rozemarijn S., Simonetti, Elles R., Aarts-Riemens, Tineke, Emmelot, Maarten E., van Bloois, Louis, Martens, Anton, Verdonck, Leo F., Ebeling, Saskia B.
Published in Clinical cancer research (15.09.2006)
Published in Clinical cancer research (15.09.2006)
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Identification of a 40S Ribosomal Protein S4–Derived H-Y Epitope Able to Elicit a Lymphoblast-Specific Cytotoxic T Lymphocyte Response
IVANOV, Roman, AARTS, Tineke, HOL, Samantha, DOORNENBAL, Angeline, HAGENBEEK, Anton, PETERSEN, Eefke, EBELING, Saskia
Published in Clinical cancer research (01.03.2005)
Published in Clinical cancer research (01.03.2005)
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TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product
Straetemans, Trudy, Janssen, Anke, Jansen, Koen, Doorn, Ruud, Aarts, Tineke, van Muyden, Anna D.D., Simonis, Marieke, Bergboer, Judith, de Witte, Moniek, Sebestyen, Zsolt, Kuball, Jurgen
Published in Molecular therapy (05.02.2020)
Published in Molecular therapy (05.02.2020)
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Journal Article
Towards the Next Generation CAR T Cells with TEGs: In Vivo Efficacy — Toxicity Profile in Xenografts of Primary Human AML Disease and Healthy Bone Marrow
Straetemans, Trudy, Gan, Inez Johanna, Heijhuurs, Sabine, Kierkels, Guido, Jansen, Koen, Doorn, Ruud, Aarts, Tineke, Norrel, Haakan, Sebestyen, Zsolt, Kuball, Jurgen
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Host Dendritic Cell Vaccinations Combined with Donor Lymphocyte Infusions Induce Host and KLH Specific Immunity in Multiple Myeloma Patients
Kneppers, Evelien, Minnema, Monique C., Aarts, Tineke, Emmelot, Maarten E., Slaper-Cortenbach, Ineke, Westinga, Kasper, Mutis, Tuna, Lokhorst, Henk M.
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Lenalidomide Is Highly Effective in Patients with Relapsed Multiple Myeloma Following Allogeneic Stem Cell Transplantation and Increases the Frequency of CD4+FOXP3+ T Cells
Minnema, Monique C., van der Veer, Michael, Aarts, Tineke, Emmelot, Maarten, Mutis, Tuna, Lokhorst, Henk M.
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Induction of Potent Anti-Tumor Effects by Original and TCR-Redirected CD4 + Cytotoxic T Cells
Spaapen, Robbert M, van den Oudenalder, Kelly, van Elk, Maureen, Aarts, Tineke, Guichelaar, Teun, Groen, Richard WJ, Bloem, Andries C, Storm, Gert, Martens, Anton C, Lokhorst, Henk M, Mutis, Tuna
Published in Blood (20.11.2009)
Published in Blood (20.11.2009)
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Journal Article
Human CD4+ CD25+ Regulatory T Cells Effectively Control Xenogeneic-GvHD Induced by Autologous T Cells in Rag2−/− γc−/− Immune-Deficient Mice
Mutis, Tuna, van Rijn, Rozemarijn S., Simonetti, Elles R., Aarts, Tineke, Emmelot, Maarten, Ebeling, Saskia B.
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Journal Article
HLA-DRB116-restricted recognition of myeloid cells, including CD34^sup +^ CML progenitor cells
Ebeling, Saskia B, Ivanov, Roman, Hol, Samantha, Aarts, Tineke I
Published in British journal of haematology (01.06.2003)
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Published in British journal of haematology (01.06.2003)
Journal Article
Accessory Cells of the Microenvironment Protect Multiple Myeloma from T-Cell Cytotoxicity through Cell Adhesion-Mediated Immune Resistance
DE HAART, Sanne J, VAN DE DONK, Niels W. C. J, LOKHORST, Henk M, MARTENS, Anton C, MITSIADES, Constantine S, MUTIS, Tuna, MINNEMA, Monique C, HUANG, Julie H, AARTS-RIEMENS, Tineke, BOVENSCHEN, Niels, HUIPIN YUAN, GROEN, Richard W. J, MCMILLIN, Douglas W, JAKUBIKOVA, Jana
Published in Clinical cancer research (15.10.2013)
Published in Clinical cancer research (15.10.2013)
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Journal Article
The Survivin Suppressant YM155 Overcomes Microenvironment-Mediated Immune Resistance In a Humanized Multiple Myeloma Mouse Model
de Haart, Sanne J., Minnema, Monique C., Huang, Julie H., Aarts-Riemens, Tineke, Lokhorst, Henk, Martens, Anton, Mitsiades, Constantine S., Mutis, Tuna
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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