Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: Exploration of P2 quinazoline substituents
Nilsson, Magnus, Belfrage, Anna Karin, Lindström, Stefan, Wähling, Horst, Lindquist, Charlotta, Ayesa, Susana, Kahnberg, Pia, Pelcman, Mikael, Benkestock, Kurt, Agback, Tatiana, Vrang, Lotta, Terelius, Ylva, Wikström, Kristina, Hamelink, Elizabeth, Rydergård, Christina, Edlund, Michael, Eneroth, Anders, Raboisson, Pierre, Lin, Tse-I, de Kock, Herman, Wigerinck, Piet, Simmen, Kenneth, Samuelsson, Bertil, Rosenquist, Åsa
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
Get full text
Journal Article
Discovery of β-d-2′-deoxy-2′-dichlorouridine nucleotide prodrugs as potent inhibitors of hepatitis C virus replication
Pinho, Pedro, Kalayanov, Genadiy, Westerlind, Hans, Rosenquist, Åsa, Wähling, Horst, Sund, Christian, Almeida, Maria, Ayesa, Susana, Tejbrant, Jan, Targett-Adams, Paul, Eneroth, Anders, Lindqvist, Annelie
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Get full text
Journal Article
Solid-phase parallel synthesis and SAR of 4-amidofuran-3-one inhibitors of cathepsin S: Effect of sulfonamides P3 substituents on potency and selectivity
Ayesa, Susana, Lindquist, Charlotta, Agback, Tatiana, Benkestock, Kurt, Classon, Björn, Henderson, Ian, Hewitt, Ellen, Jansson, Katarina, Kallin, Anders, Sheppard, Dave, Samuelsson, Bertil
Published in Bioorganic & medicinal chemistry (01.02.2009)
Published in Bioorganic & medicinal chemistry (01.02.2009)
Get full text
Journal Article
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: Use of cyclopentane and cyclopentene P2-motifs
Bäck, Marcus, Johansson, Per-Ola, Wångsell, Fredrik, Thorstensson, Fredrik, Kvarnström, Ingemar, Ayesa, Susana, Wähling, Horst, Pelcman, Mikael, Jansson, Katarina, Lindström, Stefan, Wallberg, Hans, Classon, Björn, Rydergård, Christina, Vrang, Lotta, Hamelink, Elizabeth, Hallberg, Anders, Rosenquist, Åsa, Samuelsson, Bertil
Published in Bioorganic & medicinal chemistry (15.11.2007)
Published in Bioorganic & medicinal chemistry (15.11.2007)
Get full text
Journal Article
Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors
VENDEVILLE, Sandrine, NILSSON, Magnus, ENEROTH, Anders, WIKSTROM, Kristina, VRANG, Lotta, EDLUND, Michael, LINDSTRÖM, Stefan, VAN DE VREKEN, Wim, MCGOWAN, David, TAHRI, Abdellah, LILI HU, LENZ, Oliver, DE KOCK, Herman, DELOUVROY, Frederic, VAN DOOREN, Marleen, KINDERMANS, Natalie, SURLERAUX, Dominique, WIGERINCK, Piet, ROSENQUIST, Asa, SAMUELSSON, Bertil, SIMMENA, Kenneth, RABOISSON, Pierre, LINA, Tse-I, ANTONOV, Dmitry, CLASSON, Björn, AYESA, Susana, IVANOV, Vladimir, JOHANSSON, Per-Ola, KAHNBERG, Pia
Published in Bioorganic & medicinal chemistry (01.12.2008)
Published in Bioorganic & medicinal chemistry (01.12.2008)
Get full text
Journal Article
NEW CATHEPSIN S PROTEASE INHIBITORS, USEFUL IN THE TREATMENT OF E.G. AUTOIMMUNE DISORDERS, ALLERGY AND CHRONIC PAIN CONDITIONS
HEWITT ELLEN, WIKTELIUS DANIEL, JONSSON DANIEL, KLASSON BJORN, TEJBRANT JAN, LUNDGREN STINA, GRABOWSKA URSZULA, KAHNBERG PIA, AYESA SUSANA
Year of Publication 06.08.2013
Get full text
Year of Publication 06.08.2013
Patent
CYSTEINE PROTEASE INHIBITORS
HEWITT ELLEN, WIKTELIUS DANIEL, JOENSSON DANIEL, KLASSON BJOERN, LUNDGREN STINA, GRABOWSKA URSZULA, KAHNBERG PIA, AYESA SUSANA, LIND PETER, PARKES KEVIN, ODEN LOURDES, ERSMARK KAROLINA
Year of Publication 09.10.2012
Get full text
Year of Publication 09.10.2012
Patent
CYSTEINE PROTEASE INHIBITORS
HEWITT ELLEN, WIKTELIUS DANIEL, JOENSSON DANIEL, KLASSON BJOERN, GRABOWSKA URSZULA, KAHNBERG PIA, AYESA SUSANA, LIND PETER, PARKES KEVIN, CARLQUIST PETER, ODEN LOURDES, ERSMARK KAROLINA
Year of Publication 22.08.2012
Get full text
Year of Publication 22.08.2012
Patent
CYSTEINE PROTEASE INHIBITORS
JOENSSON DANIEL, WAEHLING HORST, CLASSON BJOERN, KAHNBERG PIA, AYESA SUSANA, IVANOV VLADIMIR, ODEN LOURDES, NILSSON MAGNUS, HEWITT ELLEN, GRABOWSKA URSZULA, BELFRAGE ANNA KARIN, LIND PETER, PELCMAN MIKAEL
Year of Publication 15.09.2011
Get full text
Year of Publication 15.09.2011
Patent
RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
AYESA, Susana, BYLUND, Johan, ERSMARK, Karolina, SALVADOR ODEN, Lourdes
Year of Publication 01.03.2018
Get full text
Year of Publication 01.03.2018
Patent
RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
AYESA, Susana, SEHGELMEBLE, Fernando, BYLUND, Johan, ERSMARK, Karolina, SALVADOR ODEN, Lourdes
Year of Publication 01.03.2018
Get full text
Year of Publication 01.03.2018
Patent
3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)
KUHN, Cyrille, AYESA, Susana, LEIJONMARCK, Marie, GHIRO, Elise, BERTRAND, Megan, STURINO, Claudio, BROCHU, Christian, WESTERLIND, Hans, SEHGELMEBLE, Fernando, BYLUND, Johan, ERSMARK, Karolina, KALAYANOV, Gennadiy, WÄHLING, Horst, SALVADOR ODEN, Lourdes
Year of Publication 03.06.2020
Get full text
Year of Publication 03.06.2020
Patent
HCV NS-3 Serinproteasehemmere
Kvarnstrom, Ingemar, Thorstensson, Fredrik, Rakos, Lazlo, Ayesa, Susana, Classon, Björn, Samuelsson, Bertil, Rosenquist, Åsa, Johansson, Per-Ola
Year of Publication 06.06.2017
Get full text
Year of Publication 06.06.2017
Patent
RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
KUHN, Cyrille, AYESA, Susana, LEIJONMARCK, Marie, GHIRO, Elise, BERTRAND, Megan, STURINO, Claudio, BROCHU, Christian, WESTERLIND, Hans, SEHGELMEBLE, Fernando, BYLUND, Johan, ERSMARK, Karolina, KALAYANOV, Gennadiy, WÄHLING, Horst, SALVADOR ODEN, Lourdes
Year of Publication 13.03.2019
Get full text
Year of Publication 13.03.2019
Patent
RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
KUHN, Cyrille, AYESA, Susana, LEIJONMARCK, Marie, GHIRO, Elise, BERTRAND, Megan, STURINO, Claudio, BROCHU, Christian, WESTERLIND, Hans, SEHGELMEBLE, Fernando, LUNDGREN, Stina, BYLUND, Johan, ERSMARK, Karolina, KALAYANOV, Gennadiy, ODEN, Lourdes Salvador, WAHLING, Horst
Year of Publication 03.01.2019
Get full text
Year of Publication 03.01.2019
Patent
3-((4-ISOQUINOLIN-3-YL)METHYL)-1H-IMIDAZO[4,5-C]PYRIDIN-2(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)
KUHN, Cyrille, AYESA, Susana, LEIJONMARCK, Marie, GHIRO, Elise, BERTRAND, Megan, STURINO, Claudio, BROCHU, Christian, WESTERLIND, Hans, SEHGELMEBLE, Fernando, BYLUND, Johan, ERSMARK, Karolina, KALAYANOV, Gennadiy, WÄHLING, Horst, SALVADOR ODEN, Lourdes
Year of Publication 06.06.2018
Get full text
Year of Publication 06.06.2018
Patent
CYSTEINE PROTEASE INHIBITORS
AYESA, SUSANA, JOENSSON, DANIEL, KAHNBERG, PIA, GRABOWSKA, URSZULA, HEWITT, ELLEN
Year of Publication 13.12.2012
Get full text
Year of Publication 13.12.2012
Patent
Respiratory syncytial virus inhibitors
Salvador Oden, Lourdes, Ersmark, Karolina, Brochu, Christian, Sturino, Claudio, Bylund, Johan, Westerlind, Hans, Ayesa, Susana, Sehgelmeble, Fernando, Wähling, Horst, Ghiro, Elise, Bertrand, Megan, Kalayanov, Gennadiy, Leijonmarck, Marie, Kuhn, Cyrille
Year of Publication 08.02.2018
Get full text
Year of Publication 08.02.2018
Patent