A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
Chang, Diana, Nalls, Mike A, Hallgrímsdóttir, Ingileif B, Hunkapiller, Julie, van der Brug, Marcel, Cai, Fang, Kerchner, Geoffrey A, Ayalon, Gai, Bingol, Baris, Sheng, Morgan, Hinds, David, Behrens, Timothy W, Singleton, Andrew B, Bhangale, Tushar R, Graham, Robert R
Published in Nature genetics (01.10.2017)
Published in Nature genetics (01.10.2017)
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Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
Friedman, Brad A., Srinivasan, Karpagam, Ayalon, Gai, Meilandt, William J., Lin, Han, Huntley, Melanie A., Cao, Yi, Lee, Seung-Hye, Haddick, Patrick C.G., Ngu, Hai, Modrusan, Zora, Larson, Jessica L., Kaminker, Joshua S., van der Brug, Marcel P., Hansen, David V.
Published in Cell reports (Cambridge) (16.01.2018)
Published in Cell reports (Cambridge) (16.01.2018)
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[18F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer’s disease
Sanabria Bohórquez, Sandra, Marik, Jan, Ogasawara, Annie, Tinianow, Jeff N., Gill, Herman S., Barret, Olivier, Tamagnan, Gilles, Alagille, David, Ayalon, Gai, Manser, Paul, Bengtsson, Thomas, Ward, Michael, Williams, Simon-Peter, Kerchner, Geoffrey A., Seibyl, John P., Marek, Kenneth, Weimer, Robby M.
Published in European journal of nuclear medicine and molecular imaging (01.09.2019)
Published in European journal of nuclear medicine and molecular imaging (01.09.2019)
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Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement
Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded, Chan, Ruby, Ernst, James A., DiCara, Danielle, Hotzel, Isidro, Srinivasan, Karpagam, Hansen, David V., Atwal, Jasvinder, Lu, Yanmei, Bumbaca, Daniela, Pfeifer, Andrea, Watts, Ryan J., Muhs, Andreas, Scearce-Levie, Kimberly, Ayalon, Gai
Published in Cell reports (Cambridge) (09.08.2016)
Published in Cell reports (Cambridge) (09.08.2016)
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Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease
Brendza, Robert, Gao, Xiaoying, Stark, Kimberly L., Lin, Han, Lee, Seung-Hye, Hu, Changyun, Cai, Hao, DiCara, Danielle, Hsiao, Yi-Chun, Ngu, Hai, Foreman, Oded, Baca, Miriam, Dohse, Monika, Fortin, Jean-Phillipe, Corpuz, Racquel, Seshasayee, Dhaya, Easton, Amy, Ayalon, Gai, Hötzel, Isidro, Chih, Ben
Published in Neurobiology of disease (01.02.2023)
Published in Neurobiology of disease (01.02.2023)
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Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA)
Feng, Zhihua, Lam, Steven, Tenn, Elena-Marie Sandino, Ghosh, Arundhati Sengupta, Cantor, Sarah, Zhang, Wei, Yen, Pei-Fen, Chen, Karen S., Burden, Steven, Paushkin, Sergey, Ayalon, Gai, Ko, Chien-Ping
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Calpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
Chen, Hsu-Hsin, Liu, Peter, Auger, Paul, Lee, Seung-Hye, Adolfsson, Oskar, Rey-Bellet, Lorianne, Lafrance-Vanasse, Julien, Friedman, Brad A., Pihlgren, Maria, Muhs, Andreas, Pfeifer, Andrea, Ernst, James, Ayalon, Gai, Wildsmith, Kristin R., Beach, Thomas G., van der Brug, Marcel P.
Published in Scientific reports (13.11.2018)
Published in Scientific reports (13.11.2018)
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Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration
Pozniak, Christine D, Sengupta Ghosh, Arundhati, Gogineni, Alvin, Hanson, Jesse E, Lee, Seung-Hye, Larson, Jessica L, Solanoy, Hilda, Bustos, Daisy, Li, Hong, Ngu, Hai, Jubb, Adrian M, Ayalon, Gai, Wu, Jiansheng, Scearce-Levie, Kimberly, Zhou, Qiang, Weimer, Robby M, Kirkpatrick, Donald S, Lewcock, Joseph W
Published in The Journal of experimental medicine (18.11.2013)
Published in The Journal of experimental medicine (18.11.2013)
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Stargazin Reduces Desensitization and Slows Deactivation of the AMPA-Type Glutamate Receptors
Priel, Avi, Kolleker, Alexander, Ayalon, Gai, Gillor, Moshe, Osten, Pavel, Stern-Bach, Yael
Published in The Journal of neuroscience (09.03.2005)
Published in The Journal of neuroscience (09.03.2005)
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Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study
Iida, Megan A, Farrell, Kurt, Walker, Jamie M, Richardson, Timothy E, Marx, Gabriel A, Bryce, Clare H, Purohit, Dushyant, Ayalon, Gai, Beach, Thomas G, Bigio, Eileen H, Cortes, Etty P, Gearing, Marla, Haroutunian, Vahram, McMillan, Corey T, Lee, Edward B, Dickson, Dennis W, McKee, Ann C, Stein, Thor D, Trojanowski, John Q, Woltjer, Randall L, Kovacs, Gabor G, Kofler, Julia K, Kaye, Jeffrey, White, 3rd, Charles L, Crary, John F
Published in Acta neuropathologica communications (05.08.2021)
Published in Acta neuropathologica communications (05.08.2021)
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Corrigendum to “Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS” Neurobiology of Disease 124 (2019) 340–352
Sengupta-Ghosh, Arundhati, Dominguez, Sara L., Xie, Luke, Barck, Kai H., Jiang, Zhiyu, Earr, Timothy, Imperio, Jose, Phu, Lilian, Budayeva, Hanna G., Kirkpatrick, Donald S., Cai, Hao, He, Dongping, Eastham-Anderson, Jeffrey, Ngu, Hai, Foreman, Oded, Hedehus, Maj, Reichelt, Michael, Hotzel, Isidro, Shang, Yonglei, Carano, Richard A.D., Ayalon, Gai, Easton, Amy
Published in Neurobiology of disease (01.12.2019)
Published in Neurobiology of disease (01.12.2019)
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Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS
Sengupta-Ghosh, Arundhati, Dominguez, Sara L., Xie, Luke, Barck, Kai H., Jiang, Zhiyu, Earr, Timothy, Imperio, Jose, Phu, Lilian, Budayeva, Hanna G., Kirkpatrick, Donald S., Cai, Hao, Eastham-Anderson, Jeffrey, Ngu, Hai, Foreman, Oded, Hedehus, Maj, Reichelt, Michael, Hotzel, Isidro, Shang, Yonglei, Carano, Richard A.D., Ayalon, Gai, Easton, Amy
Published in Neurobiology of disease (01.04.2019)
Published in Neurobiology of disease (01.04.2019)
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P4‐351: Evaluation of TAU Burden in a Cross‐Sectional Cohort of Alzheimer’S Disease Subjects Using [18F]GTP1 (GENENTECH TAU PROBE 1)
Bohorquez, Sandra Sanabria, Barret, Olivier, Tamagnan, Gilles, Alagille, David, Marik, Jan, Ayalon, Gai, Bengtsson, Thomas, Crespigny, Alex, Jennings, Danna, Seibyl, John P., Marek, Kenneth, Weimer, Robby, Kerchner, Geoffrey A.
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Two Regions in the N-terminal Domain of Ionotropic Glutamate Receptor 3 Form the Subunit Oligomerization Interfaces That Control Subtype-specific Receptor Assembly
Ayalon, Gai, Segev, Eitan, Elgavish, Sharona, Stern-Bach, Yael
Published in The Journal of biological chemistry (15.04.2005)
Published in The Journal of biological chemistry (15.04.2005)
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Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases
Budayeva, Hanna G., Sengupta-Ghosh, Arundhati, Phu, Lilian, Moffat, John G., Ayalon, Gai, Kirkpatrick, Donald S.
Published in Molecular & cellular proteomics (01.04.2022)
Published in Molecular & cellular proteomics (01.04.2022)
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Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease
Ayalon, Gai, Lee, Seung-Hye, Adolfsson, Oskar, Foo-Atkins, Corinne, Atwal, Jasvinder K, Blendstrup, Mira, Booler, Helen, Bravo, Joseph, Brendza, Robert, Brunstein, Flavia, Chan, Ruby, Chandra, Priya, Couch, Jessica A, Datwani, Akash, Demeule, Barthélemy, DiCara, Danielle, Erickson, Rich, Ernst, James A, Foreman, Oded, He, Dongping, Hötzel, Isidro, Keeley, Michael, Kwok, Michael C M, Lafrance-Vanasse, Julien, Lin, Han, Lu, Yanmei, Luk, Wilman, Manser, Paul, Muhs, Andreas, Ngu, Hai, Pfeifer, Andrea, Pihlgren, Maria, Rao, Gautham K, Scearce-Levie, Kimberly, Schauer, Stephen P, Smith, William B, Solanoy, Hilda, Teng, Edmond, Wildsmith, Kristin R, Bumbaca Yadav, Daniela, Ying, Yong, Fuji, Reina N, Kerchner, Geoffrey A
Published in Science translational medicine (12.05.2021)
Published in Science translational medicine (12.05.2021)
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Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy
Walker, Jamie M, Richardson, Timothy E, Farrell, Kurt, Iida, Megan A, Foong, Chan, Shang, Ping, Attems, Johannes, Ayalon, Gai, Beach, Thomas G, Bigio, Eileen H, Budson, Andrew, Cairns, Nigel J, Corrada, María, Cortes, Etty, Dickson, Dennis W, Fischer, Peter, Flanagan, Margaret E, Franklin, Erin, Gearing, Marla, Glass, Jonathan, Hansen, Lawrence A, Haroutunian, Vahram, Hof, Patrick R, Honig, Lawrence, Kawas, Claudia, Keene, C Dirk, Kofler, Julia, Kovacs, Gabor G, Lee, Edward B, Lutz, Mirjam I, Mao, Qinwen, Masliah, Eliezer, McKee, Ann C, McMillan, Corey T, Mesulam, M Marsel, Murray, Melissa, Nelson, Peter T, Perrin, Richard, Pham, Thao, Poon, Wayne, Purohit, Dushyant P, Rissman, Robert A, Sakai, Kenji, Sano, Mary, Schneider, Julie A, Stein, Thor D, Teich, Andrew F, Trojanowski, John Q, Troncoso, Juan C, Vonsattel, Jean-Paul, Weintraub, Sandra, Wolk, David A, Woltjer, Randall L, Yamada, Masahito, Yu, Lei, White, Charles L, Crary, John F
Published in Journal of neuropathology and experimental neurology (01.02.2021)
Published in Journal of neuropathology and experimental neurology (01.02.2021)
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eP235: Interim results of the Vigilan observational study: clinical characteristics of creatine transporter deficiency
Miller, Judith, Bianconi, Simona, Anselm, Irina, Barshop, Bruce, Berry-Kravis, Elizabeth, Cecil, Kim, Hannah-Shmouni, Fady, Koeberl, Dwight, Longo, Nicola, Mercimek-Andrews, Saadet, Porter, Forbes, Sutton, V. Reid, Ayalon, Gai, Blair, Susan, Brandabur, Melanie, Rees, Linda, Zhang, Lin, Thurm, Audrey
Published in Genetics in medicine (01.03.2022)
Published in Genetics in medicine (01.03.2022)
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