An Industry Perspective on the Monitoring of Subvisible Particles as a Quality Attribute for Protein Therapeutics
Singh, Satish K., Afonina, Nataliya, Awwad, Michel, Bechtold-Peters, Karoline, Blue, Jeffrey T., Chou, Danny, Cromwell, Mary, Krause, Hans-Juergen, Mahler, Hanns-Christian, Meyer, Brian K., Narhi, Linda, Nesta, Doug P., Spitznagel, Thomas
Published in Journal of pharmaceutical sciences (01.08.2010)
Published in Journal of pharmaceutical sciences (01.08.2010)
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Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue
Sachs, David H, Yamada, Kazuhiko, Yazawa, Koji, Shimizu, Akira, Iwanaga, Takehiro, Hisashi, Yosuke, Nuhn, Matthew, O'Malley, Patricia, Nobori, Shuji, Vagefi, Parsia A, Patience, Clive, Fishman, Jay, Cooper, David K C, Hawley, Robert J, Greenstein, Julia, Schuurman, Henk-Jan, Awwad, Michel, Sykes, Megan
Published in Nature medicine (01.01.2005)
Published in Nature medicine (01.01.2005)
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Heart transplantation in baboons using α1,3-galactosyltransferase gene-knockout pigs as donors: initial experience
Cooper, David K C, Kuwaki, Kenji, Tseng, Yau-Lin, Dor, Frank J M F, Shimizu, Akira, Houser, Stuart L, Sanderson, Todd M, Lancos, Courtney J, Prabharasuth, Derek D, Cheng, Jane, Moran, Kathleen, Hisashi, Yosuke, Mueller, Nicolas, Yamada, Kazuhiko, Greenstein, Julia L, Hawley, Robert J, Patience, Clive, Awwad, Michel, Fishman, Jay A, Robson, Simon C, Schuurman, Henk-Jan, Sachs, David H
Published in Nature medicine (01.01.2005)
Published in Nature medicine (01.01.2005)
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Complex Pharmacokinetics of a Humanized Antibody Against Human Amyloid Beta Peptide, Anti-Abeta Ab2, in Nonclinical Species
Vugmeyster, Yulia, Szklut, Pam, Wensel, David, Ross, John, Xu, Xin, Awwad, Michel, Gill, Davinder, Tchistiakov, Lioudmila, Warner, Garvin
Published in Pharmaceutical research (01.07.2011)
Published in Pharmaceutical research (01.07.2011)
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Prolonged survival of porcine hepatocytes in cynomolgus monkeys
Nagata, Hideo, Nishitai, Ryuta, Shirota, Chiyoe, Zhang, Jia-Lin, Koch, Cody A, Cai, Jin, Awwad, Michel, Schuurman, Henk-Jan, Christians, Uwe, Abe, Michio, Baranowska-Kortylewicz, Janina, Platt, Jeffrey L, Fox, Ira J
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2007)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2007)
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Suppression of Natural and Elicited Antibodies in Pig‐to‐Baboon Heart Transplantation Using a Human Anti‐Human CD154 mAb‐Based Regimen
Kuwaki, Kenji, Knosalla, Christoph, Dor, Frank J. M. F., Gollackner, Bernd, Tseng, Yau‐Lin, Houser, Stuart, Mueller, Nicolas, Prabharasuth, Derek, Alt, Amy, Moran, Kathy, Cheng, Jane, Behdad, Amir, Sachs, David H., Fishman, Jay A., Schuurman, Henk‐Jan, Awwad, Michel, Cooper, David K. C.
Published in American journal of transplantation (01.03.2004)
Published in American journal of transplantation (01.03.2004)
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Investigation of potential carbohydrate antigen targets for human and baboon antibodies
Yeh, Peter, Ezzelarab, Mohamed, Bovin, Nicolai, Hara, Hidetaka, Long, Cassandra, Tomiyama, Koji, Sun, Frank, Ayares, David, Awwad, Michel, Cooper, David K. C.
Published in Xenotransplantation (Københaven) (01.05.2010)
Published in Xenotransplantation (Københaven) (01.05.2010)
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How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
KRAYNOV, Eugenia, MARTIN, Steven W, AWWAD, Michel, WANG, Diane, HURST, Susan, FAHMI, Odette A, DOWTY, Martin, CRONENBERGER, Carol, LOI, Cho-Ming, KUANG, Bing, FIELDS, Owen, FOUNTAIN, Scott
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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Allosensitized humans are at no greater risk of humoral rejection of GT-KO pig organs than other humans
Hara, Hidetaka, Ezzelarab, Mohamed, Rood, Pleunie P. M., Lin, Yih Jyh, Busch, Jamie, Ibrahim, Zuhaib, Zhu, Xiaocheng, Ball, Suyapa, Ayares, David, Zeevi, Adriana, Awwad, Michel, Cooper, David K. C.
Published in Xenotransplantation (Københaven) (01.07.2006)
Published in Xenotransplantation (Københaven) (01.07.2006)
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How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential: TABLE 1
Kraynov, Eugenia, Martin, Steven W., Hurst, Susan, Fahmi, Odette A., Dowty, Martin, Cronenberger, Carol, Loi, Cho-Ming, Kuang, Bing, Fields, Owen, Fountain, Scott, Awwad, Michel, Wang, Diane
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation
Gollackner, Bernd, Mueller, Nicolas J, Houser, Stuart, Qawi, Imrana, Soizic, Daniel, Knosalla, Christoph, Buhler, Leo, Dor, Frank J M F, Awwad, Michel, Sachs, David H, Cooper, David K C, Robson, Simon C, Fishman, Jay A
Published in Transplantation (15.06.2003)
Published in Transplantation (15.06.2003)
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Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness
Barth, Rolf N, Yamamoto, Shin, LaMattina, John C, Kumagai, Naoki, Kitamura, Hiroshi, Vagefi, Parsia A, Awwad, Michel, Colvin, Robert B, Cooper, David K C, Sykes, Megan, Sachs, David H, Yamada, Kazuhiko
Published in Transplantation (27.05.2003)
Published in Transplantation (27.05.2003)
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Journal Article
Antibodies directed to pig non-Gal antigens in naïve and sensitized baboons
Ezzelarab, Mohamed, Hara, Hidetaka, Busch, Jamie, Rood, Pleunie P. M., Zhu, Xiaocheng, Ibrahim, Zuhaib, Ball, Suyapa, Ayares, David, Awwad, Michel, Cooper, David K. C.
Published in Xenotransplantation (Københaven) (01.09.2006)
Published in Xenotransplantation (Københaven) (01.09.2006)
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Journal Article
Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution
Yamamoto, Shin, Lavelle, John M, Vagefi, Parsia A, Arakawa, Hitoshi, Samelson-Jones, Emma, Moran, Shannon, Teranishi, Katsuhito, Kamano, Chisako, Fishman, Jay, Awwad, Michel, Neville, David M, Shimizu, Akira, Sykes, Megan, Sachs, David H, Yamada, Kazuhiko
Published in Transplantation (27.12.2005)
Published in Transplantation (27.12.2005)
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Journal Article
Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption
Kozlowski, T, Shimizu, A, Lambrigts, D, Yamada, K, Fuchimoto, Y, Glaser, R, Monroy, R, Xu, Y, Awwad, M, Colvin, R B, Cosimi, A B, Robson, S C, Fishman, J, Spitzer, T R, Cooper, D K, Sachs, D H
Published in Transplantation (15.01.1999)
Published in Transplantation (15.01.1999)
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Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here?
Cooper, David K C, Dorling, Anthony, Pierson, 3rd, Richard N, Rees, Michael, Seebach, Jorg, Yazer, Mark, Ohdan, Hideki, Awwad, Michel, Ayares, David
Published in Transplantation (15.07.2007)
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Published in Transplantation (15.07.2007)
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