From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations
Veit, Gudio, Avramescu, Radu G, Chiang, Annette N, Houck, Scott A, Cai, Zhiwei, Peters, Kathryn W, Hong, Jeong S, Pollard, Harvey B, Guggino, William B, Balch, William E, Skach, William R, Cutting, Garry R, Frizzell, Raymond A, Sheppard, David N, Cyr, Douglas M, Sorscher, Eric J, Brodsky, Jeffrey L, Lukacs, Gergely L
Published in Molecular biology of the cell (01.02.2016)
Published in Molecular biology of the cell (01.02.2016)
Get full text
Journal Article
Structure-guided combination therapy to potently improve the function of mutant CFTRs
Veit, Guido, Xu, Haijin, Dreano, Elise, Avramescu, Radu G., Bagdany, Miklos, Beitel, Lenore K., Roldan, Ariel, Hancock, Mark A., Lay, Cecilia, Li, Wei, Morin, Katelin, Gao, Sandra, Mak, Puiying A., Ainscow, Edward, Orth, Anthony P., McNamara, Peter, Edelman, Aleksander, Frenkiel, Saul, Matouk, Elias, Sermet-Gaudelus, Isabelle, Barnes, William G., Lukacs, Gergely L.
Published in Nature medicine (01.11.2018)
Published in Nature medicine (01.11.2018)
Get full text
Journal Article
Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression
Veit, Guido, Avramescu, Radu G, Perdomo, Doranda, Phuan, Puay-Wah, Bagdany, Miklos, Apaja, Pirjo M, Borot, Florence, Szollosi, Daniel, Wu, Yu-Sheng, Finkbeiner, Walter E, Hegedus, Tamas, Verkman, Alan S, Lukacs, Gergely L
Published in Science translational medicine (23.07.2014)
Published in Science translational medicine (23.07.2014)
Get more information
Journal Article
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice
Dimitrov, Vassil, Bouttier, Manuella, Boukhaled, Giselle, Salehi-Tabar, Reyhaneh, Avramescu, Radu G., Memari, Babak, Hasaj, Benedeta, Lukacs, Gergely L., Krawczyk, Connie M., White, John H.
Published in The Journal of biological chemistry (15.12.2017)
Published in The Journal of biological chemistry (15.12.2017)
Get full text
Journal Article
Mutation-specific downregulation of CFTR2 variants by gating potentiators
Avramescu, Radu G, Kai, Yukari, Xu, Haijin, Bidaud-Meynard, Aurélien, Schnúr, Andrea, Frenkiel, Saul, Matouk, Elias, Veit, Guido, Lukacs, Gergely L
Published in Human molecular genetics (15.12.2017)
Published in Human molecular genetics (15.12.2017)
Get full text
Journal Article
Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell
Bagdany, Miklos, Veit, Guido, Fukuda, Ryosuke, Avramescu, Radu G., Okiyoneda, Tsukasa, Baaklini, Imad, Singh, Jay, Sovak, Guy, Xu, Haijin, Apaja, Pirjo M., Sattin, Sara, Beitel, Lenore K., Roldan, Ariel, Colombo, Giorgio, Balch, William, Young, Jason C., Lukacs, Gergely L.
Published in Nature communications (30.08.2017)
Published in Nature communications (30.08.2017)
Get full text
Journal Article
Correctors and Potentiators Rescue Function of the Truncated W1282X-Cystic Fibrosis Transmembrane Regulator (CFTR) Translation Product
Haggie, Peter M., Phuan, Puay-Wah, Tan, Joseph-Anthony, Xu, Haijin, Avramescu, Radu G., Perdomo, Doranda, Zlock, Lorna, Nielson, Dennis W., Finkbeiner, Walter E., Lukacs, Gergely L., Verkman, Alan S.
Published in The Journal of biological chemistry (20.01.2017)
Published in The Journal of biological chemistry (20.01.2017)
Get full text
Journal Article
Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice
Reynolds, Lauren M., Hernandez, Giovanni, MacGowan, Del, Popescu, Christina, Nouel, Dominique, Cuesta, Santiago, Burke, Samuel, Savell, Katherine E., Zhao, Janet, Restrepo-Lozano, Jose Maria, Giroux, Michel, Israel, Sonia, Orsini, Taylor, He, Susan, Wodzinski, Michael, Avramescu, Radu G., Pokinko, Matthew, Epelbaum, Julia G., Niu, Zhipeng, Pantoja-Urbán, Andrea Harée, Trudeau, Louis-Éric, Kolb, Bryan, Day, Jeremy J., Flores, Cecilia
Published in Nature communications (07.07.2023)
Published in Nature communications (07.07.2023)
Get full text
Journal Article
Mutation-specific dual potentiators maximize rescue of CFTR gating mutants
Veit, Guido, Da Fonte, Dillon F., Avramescu, Radu G., Premchandar, Aiswarya, Bagdany, Miklos, Xu, Haijin, Bensinger, Dennis, Stubba, Daniel, Schmidt, Boris, Matouk, Elias, Lukacs, Gergely L.
Published in Journal of cystic fibrosis (01.03.2020)
Published in Journal of cystic fibrosis (01.03.2020)
Get full text
Journal Article
The scheduling of adolescence with Netrin-1 and UNC5C
Hoops, Daniel, Kyne, Robert, Salameh, Samer, MacGowan, Del, Avramescu, Radu Gabriel, Ewing, Elise, He, Alina Tao, Orsini, Taylor, Durand, Anais, Popescu, Christina, Zhao, Janet Mengyi, Shatz, Kelcie, Li, LiPing, Carroll, Quinn, Liu, Guofa, Paul, Matthew J, Flores, Cecilia
Published in eLife (26.07.2024)
Published in eLife (26.07.2024)
Get full text
Journal Article
Awakening the dormant: Role of axonal guidance cues in stress-induced reorganization of the adult prefrontal cortex leading to depression-like behavior
Mahmud, Ashraf, Avramescu, Radu Gabriel, Niu, Zhipeng, Flores, Cecilia
Published in Frontiers in neural circuits (24.03.2023)
Published in Frontiers in neural circuits (24.03.2023)
Get full text
Journal Article
The scheduling of adolescence with Netrin-1 and UNC5C
Hoops, Daniel, Kyne, Robert, Salameh, Samer, MacGowan, Del, Avramescu, Radu Gabriel, Ewing, Elise, He, Alina Tao, Orsini, Taylor, Durand, Anais, Popescu, Christina, Zhao, Janet Mengyi, Shatz, Kelcie, Li, LiPing, Carroll, Quinn, Liu, Guofa, Paul, Matthew J, Flores, Cecilia
Published in eLife (26.07.2024)
Published in eLife (26.07.2024)
Get full text
Journal Article
Turnaround Strategies for Customer Centric Operations: Turn-by-Turn Directions on the Path to Recovery
Published in The International journal of conflict management
(29.06.2012)
Get full text
Journal Article
The scheduling of adolescence with Netrin-1 and UNC5C
Hoops, Daniel, Kyne, Robert F, Salameh, Samer, MacGowan, Del, Avramescu, Radu G, Ewing, Elise, He, Alina T, Orsini, Taylor, Durand, Anais, Popescu, Christina, Zhao, Janet M, Schatz, Kelcie C, Li, LiPing, Carroll, Quinn E, Liu, Guofa, Paul, Matthew J, Flores, Cecilia
Published in bioRxiv (17.04.2024)
Published in bioRxiv (17.04.2024)
Get full text
Journal Article