Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs
Martens, Sofie, Hofmans, Sam, Declercq, Wim, Augustyns, Koen, Vandenabeele, Peter
Published in Trends in pharmacological sciences (Regular ed.) (01.03.2020)
Published in Trends in pharmacological sciences (Regular ed.) (01.03.2020)
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Journal Article
Targeting ferroptosis protects against experimental (multi)organ dysfunction and death
Van Coillie, Samya, Van San, Emily, Goetschalckx, Ines, Wiernicki, Bartosz, Mukhopadhyay, Banibrata, Tonnus, Wulf, Choi, Sze Men, Roelandt, Ria, Dumitrascu, Catalina, Lamberts, Ludwig, Dams, Geert, Weyts, Wannes, Huysentruyt, Jelle, Hassannia, Behrouz, Ingold, Irina, Lele, Suhas, Meyer, Evelyne, Berg, Maya, Seurinck, Ruth, Saeys, Yvan, Vermeulen, An, van Nuijs, Alexander L. N., Conrad, Marcus, Linkermann, Andreas, Rajapurkar, Mohan, Vandenabeele, Peter, Hoste, Eric, Augustyns, Koen, Vanden Berghe, Tom
Published in Nature communications (24.02.2022)
Published in Nature communications (24.02.2022)
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Journal Article
ClpP Protease, a Promising Antimicrobial Target
Moreno-Cinos, Carlos, Goossens, Kenneth, Salado, Irene G, Van Der Veken, Pieter, De Winter, Hans, Augustyns, Koen
Published in International journal of molecular sciences (07.05.2019)
Published in International journal of molecular sciences (07.05.2019)
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Journal Article
Regulation of intestinal permeability: The role of proteases
Van Spaendonk, Hanne, Ceuleers, Hannah, Witters, Leonie, Patteet, Eveline, Joossens, Jurgen, Augustyns, Koen, Lambeir, Anne-Marie, De Meester, Ingrid, De Man, Joris G, De Winter, Benedicte Y
Published in World journal of gastroenterology : WJG (28.03.2017)
Published in World journal of gastroenterology : WJG (28.03.2017)
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Journal Article
Selected strategies to fight pathogenic bacteria
Plotniece, Aiva, Sobolev, Arkadij, Supuran, Claudiu T., Carta, Fabrizio, Björkling, Fredrik, Franzyk, Henrik, Yli-Kauhaluoma, Jari, Augustyns, Koen, Cos, Paul, De Vooght, Linda, Govaerts, Matthias, Aizawa, Juliana, Tammela, Päivi, Žalubovskis, Raivis
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Journal Article
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancer
de Laat, Vincent, Topal, Halit, Spotbeen, Xander, Talebi, Ali, Dehairs, Jonas, Idkowiak, Jakub, Vanderhoydonc, Frank, Ostyn, Tessa, Zhao, Peihua, Jacquemyn, Maarten, Wölk, Michele, Sablina, Anna, Augustyns, Koen, Vanden Berghe, Tom, Roskams, Tania, Daelemans, Dirk, Fedorova, Maria, Topal, Baki, Swinnen, Johannes V.
Published in Nature communications (02.10.2024)
Published in Nature communications (02.10.2024)
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Journal Article
Design and Synthesis of 1,3-Diarylpyrazoles and Investigation of Their Cytotoxicity and Antiparasitic Profile
Bozdag, Murat, Mertens, Freke, Matheeussen, An, Van Pelt, Natascha, Foubert, Kenn, Hermans, Nina, De Meyer, Guido R Y, Augustyns, Koen, Martinet, Wim, Caljon, Guy, Van der Veken, Pieter
Published in International journal of molecular sciences (01.05.2024)
Published in International journal of molecular sciences (01.05.2024)
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Journal Article
Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases
Ceuleers, Hannah, Van Spaendonk, Hanne, Hanning, Nikita, Heirbaut, Jelena, Lambeir, Anne-Marie, Joossens, Jurgen, Augustyns, Koen, De Man, Joris G, De Meester, Ingrid, De Winter, Benedicte Y
Published in World journal of gastroenterology : WJG (21.12.2016)
Published in World journal of gastroenterology : WJG (21.12.2016)
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Journal Article
Identification and Characterization of Approved Drugs and Drug-Like Compounds as Covalent Escherichia coli ClpP Inhibitors
Sassetti, Elisa, Durante Cruz, Cristina, Tammela, Päivi, Winterhalter, Mathias, Augustyns, Koen, Gribbon, Philip, Windshügel, Björn
Published in International journal of molecular sciences (31.05.2019)
Published in International journal of molecular sciences (31.05.2019)
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Journal Article
Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
Jansen, Koen, Heirbaut, Leen, Verkerk, Robert, Cheng, Jonathan D, Joossens, Jurgen, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Journal Article
Trans-cyclooctene—a Swiss army knife for bioorthogonal chemistry: exploring the synthesis, reactivity, and applications in biomedical breakthroughs
Adhikari, Karuna, Vanermen, Maarten, Da Silva, Gustavo, Van den Wyngaert, Tim, Augustyns, Koen, Elvas, Filipe
Published in EJNMMI radiopharmacy and chemistry (06.06.2024)
Published in EJNMMI radiopharmacy and chemistry (06.06.2024)
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Journal Article
To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?
Zheng, Yang, Schroeder, Susanne, Kanev, Georgi K, Botros, Sanaa S, William, Samia, Sabra, Abdel-Nasser A, Maes, Louis, Caljon, Guy, Gil, Carmen, Martinez, Ana, Salado, Irene G, Augustyns, Koen, Edink, Ewald, Sijm, Maarten, de Heuvel, Erik, de Esch, Iwan J P, van der Meer, Tiffany, Siderius, Marco, Sterk, Geert Jan, Brown, David, Leurs, Rob
Published in International journal of molecular sciences (06.04.2023)
Published in International journal of molecular sciences (06.04.2023)
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Journal Article
Characterization of Structurally Diverse 18F‑Labeled d‑TCO Derivatives as a PET Probe for Bioorthogonal Pretargeted Imaging
Adhikari, Karuna, Dewulf, Jonatan, Vangestel, Christel, Van der Veken, Pieter, Stroobants, Sigrid, Elvas, Filipe, Augustyns, Koen
Published in ACS omega (17.10.2023)
Published in ACS omega (17.10.2023)
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Journal Article
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis
Matheeussen, Veerle, Waumans, Yannick, Martinet, Wim, Van Goethem, Sebastiaan, Van der Veken, Pieter, Scharpé, Simon, Augustyns, Koen, De Meyer, Guido R. Y., De Meester, Ingrid
Published in Basic research in cardiology (01.05.2013)
Published in Basic research in cardiology (01.05.2013)
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Journal Article
Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling
Rea, Dean, Van Elzen, Roos, De Winter, Hans, Van Goethem, Sebastiaan, Landuyt, Bart, Luyten, Walter, Schoofs, Liliane, Van Der Veken, Pieter, Augustyns, Koen, De Meester, Ingrid, Fülöp, Vilmos, Lambeir, Anne-Marie
Published in European journal of medicinal chemistry (20.10.2017)
Published in European journal of medicinal chemistry (20.10.2017)
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Journal Article
A Novel Ferroptosis Inhibitor UAMC-3203, a Potential Treatment for Corneal Epithelial Wound
Balla, Anusha, Tran, Bao, Valtari, Annika, Steven, Philipp, Scarpellini, Camilla, Augustyns, Koen, Urtti, Arto, Vellonen, Kati-Sisko, Ruponen, Marika
Published in Pharmaceutics (29.12.2022)
Published in Pharmaceutics (29.12.2022)
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Journal Article
A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors
Smiejkowska, Natalia, Oorts, Lauren, Van Calster, Kevin, De Vooght, Linda, Geens, Rob, Mattelaer, Henri-Philippe, Augustyns, Koen, Strelkov, Sergei V, Lamprecht, Dirk, Temmerman, Koen, Sterckx, Yann G-J, Cappoen, Davie, Cos, Paul
Published in Microbiology spectrum (05.03.2024)
Published in Microbiology spectrum (05.03.2024)
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