The immunology of multiple sclerosis
Attfield, Kathrine E, Jensen, Lise Torp, Kaufmann, Max, Friese, Manuel A, Fugger, Lars
Published in Nature reviews. Immunology (01.12.2022)
Published in Nature reviews. Immunology (01.12.2022)
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CD8+ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL‐18 serum levels in multiple sclerosis
Willing, Anne, Leach, Oliver A., Ufer, Friederike, Attfield, Kathrine E., Steinbach, Karin, Kursawe, Nina, Piedavent, Melanie, Friese, Manuel A.
Published in European journal of immunology (01.10.2014)
Published in European journal of immunology (01.10.2014)
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TNF receptor 1 genetic risk mirrors outcome of anti―TNF therapy in multiple sclerosis
GREGORY, Adam P, DENDROU, Calliope A, PRÖMEL, Simone, PUNWANI, Divya, FELCE, James H, DAVIS, Simon J, GOLD, Ralf, NIELSEN, Finn C, SIEGEL, Richard M, MANN, Matthias, BELL, John I, MCVEAN, Gil, ATTFIELD, Kathrine E, FUGGER, Lars, HAGHIKIA, Aiden, XIFARA, Dionysia K, BUTTER, Falk, POSCHMANN, Gereon, KAUR, Gurman, LAMBERT, Lydia, LEACH, Oliver A
Published in Nature (London) (23.08.2012)
Published in Nature (London) (23.08.2012)
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Structural and regulatory diversity shape HLA-C protein expression levels
Kaur, Gurman, Gras, Stephanie, Mobbs, Jesse I, Vivian, Julian P, Cortes, Adrian, Barber, Thomas, Kuttikkatte, Subita Balaram, Jensen, Lise Torp, Attfield, Kathrine E, Dendrou, Calliope A, Carrington, Mary, McVean, Gil, Purcell, Anthony W, Rossjohn, Jamie, Fugger, Lars
Published in Nature communications (26.06.2017)
Published in Nature communications (26.06.2017)
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Identification of early neurodegenerative pathways in progressive multiple sclerosis
Kaufmann, Max, Schaupp, Anna-Lena, Sun, Rosa, Coscia, Fabian, Dendrou, Calliope A, Cortes, Adrian, Kaur, Gurman, Evans, Hayley G, Mollbrink, Annelie, Navarro, José Fernández, Sonner, Jana K, Mayer, Christina, DeLuca, Gabriele C, Lundeberg, Joakim, Matthews, Paul M, Attfield, Kathrine E, Friese, Manuel A, Mann, Matthias, Fugger, Lars
Published in Nature neuroscience (01.07.2022)
Published in Nature neuroscience (01.07.2022)
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Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity
Dendrou, Calliope A, Cortes, Adrian, Shipman, Lydia, Evans, Hayley G, Attfield, Kathrine E, Jostins, Luke, Barber, Thomas, Kaur, Gurman, Kuttikkatte, Subita Balaram, Leach, Oliver A, Desel, Christiane, Faergeman, Soren L, Cheeseman, Jane, Neville, Matt J, Sawcer, Stephen, Compston, Alastair, Johnson, Adam R, Everett, Christine, Bell, John I, Karpe, Fredrik, Ultsch, Mark, Eigenbrot, Charles, McVean, Gil, Fugger, Lars
Published in Science translational medicine (02.11.2016)
Published in Science translational medicine (02.11.2016)
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Allosteric TYK2 inhibition: redefining autoimmune disease therapy beyond JAK1-3 inhibitors
Jensen, Lise Torp, Attfield, Kathrine E, Feldmann, Marc, Fugger, Lars
Published in EBioMedicine (01.11.2023)
Published in EBioMedicine (01.11.2023)
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Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations
Barrie, William, Yang, Yaoling, Irving-Pease, Evan K, Attfield, Kathrine E, Scorrano, Gabriele, Jensen, Lise Torp, Armen, Angelos P, Dimopoulos, Evangelos Antonios, Stern, Aaron, Refoyo-Martinez, Alba, Pearson, Alice, Ramsøe, Abigail, Gaunitz, Charleen, Demeter, Fabrice, Jørkov, Marie Louise S, Møller, Stig Bermann, Springborg, Bente, Klassen, Lutz, Hyldgård, Inger Marie, Wickmann, Niels, Vinner, Lasse, Korneliussen, Thorfinn Sand, Allentoft, Morten E, Sikora, Martin, Kristiansen, Kristian, Rodriguez, Santiago, Nielsen, Rasmus, Iversen, Astrid K N, Lawson, Daniel J, Fugger, Lars, Willerslev, Eske
Published in Nature (London) (11.01.2024)
Published in Nature (London) (11.01.2024)
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Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade
Kaur, Gurman, Porter, Caroline B M, Ashenberg, Orr, Lee, Jack, Riesenfeld, Samantha J, Hofree, Matan, Aggelakopoulou, Maria, Subramanian, Ayshwarya, Kuttikkatte, Subita Balaram, Attfield, Kathrine E, Desel, Christiane A E, Davies, Jessica L, Evans, Hayley G, Avraham-Davidi, Inbal, Nguyen, Lan T, Dionne, Danielle A, Neumann, Anna E, Jensen, Lise Torp, Barber, Thomas R, Soilleux, Elizabeth, Carrington, Mary, McVean, Gil, Rozenblatt-Rosen, Orit, Regev, Aviv, Fugger, Lars
Published in Nature communications (29.07.2022)
Published in Nature communications (29.07.2022)
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Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis
Kaufmann, Max, Evans, Hayley, Schaupp, Anna-Lena, Engler, Jan Broder, Kaur, Gurman, Willing, Anne, Kursawe, Nina, Schubert, Charlotte, Attfield, Kathrine E., Fugger, Lars, Friese, Manuel A.
Published in Med (New York, N.Y. : Online) (12.03.2021)
Published in Med (New York, N.Y. : Online) (12.03.2021)
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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases
Lippert, Anna H., Paluch, Christopher, Gaglioni, Meike, Vuong, Mai T., McColl, James, Jenkins, Edward, Fellermeyer, Martin, Clarke, Joseph, Sharma, Sumana, Moreira da Silva, Sara, Akkaya, Billur, Anzilotti, Consuelo, Morgan, Sara H., Jessup, Claire F., Körbel, Markus, Gileadi, Uzi, Leitner, Judith, Knox, Rachel, Chirifu, Mami, Huo, Jiandong, Yu, Susan, Ashman, Nicole, Lui, Yuan, Wilkinson, Ian, Attfield, Kathrine E., Fugger, Lars, Robertson, Nathan J., Lynch, Christopher J., Murray, Lynne, Steinberger, Peter, Santos, Ana Mafalda, Lee, Steven F., Cornall, Richard J., Klenerman, David, Davis, Simon J.
Published in Immunity (Cambridge, Mass.) (13.02.2024)
Published in Immunity (Cambridge, Mass.) (13.02.2024)
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Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model
VERGO, Sandra, CRANER, Matthew J, ETZENSPERGER, Ruth, ATTFIELD, Kathrine, FRIESE, Manuel A, NEWCOMBE, Jia, ESIRI, Margaret, FUGGER, Lars
Published in Brain (London, England : 1878) (01.02.2011)
Published in Brain (London, England : 1878) (01.02.2011)
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Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation
Beers, Stephen A., Chan, Claude H.T., James, Sonya, French, Ruth R., Attfield, Kathrine E., Brennan, Claire M., Ahuja, Anupama, Shlomchik, Mark J., Cragg, Mark S., Glennie, Martin J.
Published in Blood (15.11.2008)
Published in Blood (15.11.2008)
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A novel neurodegenerative spectrum disorder in patients with MLKL deficiency
Faergeman, Soren L, Evans, Hayley, Attfield, Kathrine E, Desel, Christiane, Kuttikkatte, Subita Balaram, Sommerlund, Mette, Jensen, Lise Torp, Frokiaer, Jorgen, Friese, Manuel A, Matthews, Paul M, Luchtenborg, Christian, Brügger, Britta, Oturai, Annette Bang, Dendrou, Calliope A, Fugger, Lars
Published in Cell death & disease (01.05.2020)
Published in Cell death & disease (01.05.2020)
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Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination
Francis, Anna G, Elhadd, Kariem, Camera, Valentina, Ferreira Dos Santos, Monica, Rocchi, Chiara, Adib-Samii, Poneh, Athwal, Bal, Attfield, Kathrine, Barritt, Andrew, Craner, Matthew, Fisniku, Leonora, Iversen, Astrid K N, Leach, Oliver, Matthews, Lucy, Redmond, Ian, O'Riordan, Jonathan, Scalfari, Antonio, Tanasescu, Radu, Wren, Damian, Huda, Saif, Leite, Maria Isabel, Fugger, Lars, Palace, Jacqueline
Published in Neurology : neuroimmunology & neuroinflammation (01.01.2023)
Published in Neurology : neuroimmunology & neuroinflammation (01.01.2023)
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Invariant NKT Cells Promote CD8+ Cytotoxic T Cell Responses by Inducing CD70 Expression on Dendritic Cells
Taraban, Vadim Y, Martin, Sonya, Attfield, Kathrine E, Glennie, Martin J, Elliott, Tim, Elewaut, Dirk, Van Calenbergh, Serge, Linclau, Bruno, Al-Shamkhani, Aymen
Published in The Journal of immunology (1950) (01.04.2008)
Published in The Journal of immunology (1950) (01.04.2008)
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Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor
Rühl, Geraldine, Niedl, Anna G, Patronov, Atanas, Siewert, Katherina, Pinkert, Stefan, Kalemanov, Maria, Friese, Manuel A, Attfield, Kathrine E, Antes, Iris, Hohlfeld, Reinhard, Dornmair, Klaus
Published in Neurology : neuroimmunology & neuroinflammation (01.08.2016)
Published in Neurology : neuroimmunology & neuroinflammation (01.08.2016)
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