p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells
Tarangelo, Amy, Magtanong, Leslie, Bieging-Rolett, Kathryn T., Li, Yang, Ye, Jiangbin, Attardi, Laura D., Dixon, Scott J.
Published in Cell reports (Cambridge) (16.01.2018)
Published in Cell reports (Cambridge) (16.01.2018)
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Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression
Brady, Colleen A., Jiang, Dadi, Mello, Stephano S., Johnson, Thomas M., Jarvis, Lesley A., Kozak, Margaret M., Broz, Daniela Kenzelmann, Basak, Shashwati, Park, Eunice J., McLaughlin, Margaret E., Karnezis, Anthony N., Attardi, Laura D.
Published in Cell (13.05.2011)
Published in Cell (13.05.2011)
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Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders
Calo, Eliezer, Gu, Bo, Bowen, Margot E., Aryan, Fardin, Zalc, Antoine, Liang, Jialiang, Flynn, Ryan A., Swigut, Tomek, Chang, Howard Y., Attardi, Laura D., Wysocka, Joanna
Published in Nature (London) (01.02.2018)
Published in Nature (London) (01.02.2018)
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Neat1 is a p53-inducible lincRNA essential for transformation suppression
Mello, Stephano S, Sinow, Carolyn, Raj, Nitin, Mazur, Pawel K, Bieging-Rolett, Kathryn, Broz, Daniela Kenzelmann, Imam, Jamie F Conklin, Vogel, Hannes, Wood, Laura D, Sage, Julien, Hirose, Tetsuro, Nakagawa, Shinichi, Rinn, John, Attardi, Laura D
Published in Genes & development (01.06.2017)
Published in Genes & development (01.06.2017)
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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Mazur, Pawel K, Herner, Alexander, Mello, Stephano S, Wirth, Matthias, Hausmann, Simone, Sánchez-Rivera, Francisco J, Lofgren, Shane M, Kuschma, Timo, Hahn, Stephan A, Vangala, Deepak, Trajkovic-Arsic, Marija, Gupta, Aayush, Heid, Irina, Noël, Peter B, Braren, Rickmer, Erkan, Mert, Kleeff, Jörg, Sipos, Bence, Sayles, Leanne C, Heikenwalder, Mathias, Heßmann, Elisabeth, Ellenrieder, Volker, Esposito, Irene, Jacks, Tyler, Bradner, James E, Khatri, Purvesh, Sweet-Cordero, E Alejandro, Attardi, Laura D, Schmid, Roland M, Schneider, Guenter, Sage, Julien, Siveke, Jens T
Published in Nature medicine (01.10.2015)
Published in Nature medicine (01.10.2015)
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A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response
Huarte, Maite, Guttman, Mitchell, Feldser, David, Garber, Manuel, Koziol, Magdalena J., Kenzelmann-Broz, Daniela, Khalil, Ahmad M., Zuk, Or, Amit, Ido, Rabani, Michal, Attardi, Laura D., Regev, Aviv, Lander, Eric S., Jacks, Tyler, Rinn, John L.
Published in Cell (06.08.2010)
Published in Cell (06.08.2010)
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Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
Li, Xingnan, Nadauld, Lincoln, Ootani, Akifumi, Corney, David C, Pai, Reetesh K, Gevaert, Olivier, Cantrell, Michael A, Rack, Paul G, Neal, James T, Chan, Carol W-M, Yeung, Trevor, Gong, Xue, Yuan, Jenny, Wilhelmy, Julie, Robine, Sylvie, Attardi, Laura D, Plevritis, Sylvia K, Hung, Kenneth E, Chen, Chang-Zheng, Ji, Hanlee P, Kuo, Calvin J
Published in Nature medicine (01.07.2014)
Published in Nature medicine (01.07.2014)
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Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
Kenzelmann Broz, Daniela, Spano Mello, Stephano, Bieging, Kathryn T, Jiang, Dadi, Dusek, Rachel L, Brady, Colleen A, Sidow, Arend, Attardi, Laura D
Published in Genes & development (01.05.2013)
Published in Genes & development (01.05.2013)
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Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I
Gomez-Ospina, Natalia, Scharenberg, Samantha G., Mostrel, Nathalie, Bak, Rasmus O., Mantri, Sruthi, Quadros, Rolen M., Gurumurthy, Channabasavaiah B., Lee, Ciaran, Bao, Gang, Suarez, Carlos J., Khan, Shaukat, Sawamoto, Kazuki, Tomatsu, Shunji, Raj, Nitin, Attardi, Laura D., Aurelian, Laure, Porteus, Matthew H.
Published in Nature communications (06.09.2019)
Published in Nature communications (06.09.2019)
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Cell of Origin Influences Pancreatic Cancer Subtype
Flowers, Brittany M, Xu, Hang, Mulligan, Abigail S, Hanson, Kathryn J, Seoane, Jose A, Vogel, Hannes, Curtis, Christina, Wood, Laura D, Attardi, Laura D
Published in Cancer discovery (01.03.2021)
Published in Cancer discovery (01.03.2021)
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The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes
Bowen, Margot E., McClendon, Jacob, Long, Hannah K., Sorayya, Aryo, Van Nostrand, Jeanine L., Wysocka, Joanna, Attardi, Laura D.
Published in Developmental cell (22.07.2019)
Published in Developmental cell (22.07.2019)
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The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
Moon, Eui Jung, Mello, Stephano S., Li, Caiyun G., Chi, Jen-Tsan, Thakkar, Kaushik, Kirkland, Jacob G., Lagory, Edward L., Lee, Ik Jae, Diep, Anh N., Miao, Yu, Rafat, Marjan, Vilalta, Marta, Castellini, Laura, Krieg, Adam J., Graves, Edward E., Attardi, Laura D., Giaccia, Amato J.
Published in Nature communications (14.07.2021)
Published in Nature communications (14.07.2021)
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The role of apoptosis in cancer development and treatment response
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Book Review
Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
Bieging-Rolett, Kathryn T., Kaiser, Alyssa M., Morgens, David W., Boutelle, Anthony M., Seoane, Jose A., Van Nostrand, Eric L., Zhu, Changyu, Houlihan, Shauna L., Mello, Stephano S., Yee, Brian A., McClendon, Jacob, Pierce, Sarah E., Winters, Ian P., Wang, Mengxiong, Connolly, Andrew J., Lowe, Scott W., Curtis, Christina, Yeo, Gene W., Winslow, Monte M., Bassik, Michael C., Attardi, Laura D.
Published in Molecular cell (05.11.2020)
Published in Molecular cell (05.11.2020)
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Essential role for centromeric factors following p53 loss and oncogenic transformation
Filipescu, Dan, Naughtin, Monica, Podsypanina, Katrina, Lejour, Vincent, Wilson, Laurence, Gurard-Levin, Zachary A, Orsi, Guillermo A, Simeonova, Iva, Toufektchan, Eleonore, Attardi, Laura D, Toledo, Franck, Almouzni, Geneviève
Published in Genes & development (01.03.2017)
Published in Genes & development (01.03.2017)
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