Discovery of Potent and Selective RSK Inhibitors as Biological Probes
Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Lindvall, Mika, Appleton, Brent A., Shafer, Cynthia M.
Published in Journal of medicinal chemistry (10.09.2015)
Published in Journal of medicinal chemistry (10.09.2015)
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Journal Article
Identification of N‑(4-((1R,3S,5S)‑3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies
Burger, Matthew T, Nishiguchi, Gisele, Han, Wooseok, Lan, Jiong, Simmons, Robert, Atallah, Gordana, Ding, Yu, Tamez, Victoriano, Zhang, Yanchen, Mathur, Michelle, Muller, Kristine, Bellamacina, Cornelia, Lindvall, Mika K, Zang, Richard, Huh, Kay, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Basham, Steve, Chan, Julie, Ginn, Elaine, Aycinena, Alex, Holash, Jocelyn, Castillo, Joseph, Langowski, John L, Wang, Yingyun, Chen, Min Y, Lambert, Amy, Fritsch, Christine, Kauffmann, Audry, Pfister, Estelle, Vanasse, K. Gary, Garcia, Pablo D
Published in Journal of medicinal chemistry (12.11.2015)
Published in Journal of medicinal chemistry (12.11.2015)
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Journal Article
Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer
Burger, Matthew T, Pecchi, Sabina, Wagman, Allan, Ni, Zhi-Jie, Knapp, Mark, Hendrickson, Thomas, Atallah, Gordana, Pfister, Keith, Zhang, Yanchen, Bartulis, Sarah, Frazier, Kelly, Ng, Simon, Smith, Aaron, Verhagen, Joelle, Haznedar, Joshua, Huh, Kay, Iwanowicz, Ed, Xin, Xiaohua, Menezes, Daniel, Merritt, Hanne, Lee, Isabelle, Wiesmann, Marion, Kaufman, Susan, Crawford, Kenneth, Chin, Michael, Bussiere, Dirksen, Shoemaker, Kevin, Zaror, Isabel, Maira, Sauveur-Michel, Voliva, Charles F
Published in ACS medicinal chemistry letters (13.10.2011)
Published in ACS medicinal chemistry letters (13.10.2011)
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Journal Article
Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors
Burger, Matthew T, Knapp, Mark, Wagman, Allan, Ni, Zhi-Jie, Hendrickson, Thomas, Atallah, Gordana, Zhang, Yanchen, Frazier, Kelly, Verhagen, Joelle, Pfister, Keith, Ng, Simon, Smith, Aaron, Bartulis, Sarah, Merrit, Hanne, Weismann, Marion, Xin, Xiaohua, Haznedar, Joshua, Voliva, Charles F, Iwanowicz, Ed, Pecchi, Sabina
Published in ACS medicinal chemistry letters (13.01.2011)
Published in ACS medicinal chemistry letters (13.01.2011)
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Journal Article
Synthesis and Structure–Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases
Han, Wooseok, Ding, Yu, Chen, Zheng, Langowski, John L, Bellamacina, Cornelia, Rico, Alice, Nishiguchi, Gisele A, Lan, Jiong, Atallah, Gordana, Lindvall, Mika, Lin, Song, Zang, Richard, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Garcia, Pablo, Burger, Matthew T
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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Journal Article
Design and synthesis of potent RSK inhibitors
Jain, Rama, Mathur, Michelle, Lan, Jiong, Costales, Abran, Atallah, Gordana, Ramurthy, Savithri, Subramanian, Sharadha, Setti, Lina, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen, Jefferson, Anne B., Appleton, Brent A., Lindvall, Mika, Shafer, Cynthia M.
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
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Journal Article
Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases
Nishiguchi, Gisele A., Atallah, Gordana, Bellamacina, Cornelia, Burger, Matthew T., Ding, Yu, Feucht, Paul H., Garcia, Pablo D., Han, Wooseok, Klivansky, Liana, Lindvall, Mika
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold
Nishiguchi, Gisele A., Burger, Matthew T., Han, Wooseok, Lan, Jiong, Atallah, Gordana, Tamez, Victoriano, Lindvall, Mika, Bellamacina, Cornelia, Garcia, Pablo, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Wong, Kent
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
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Journal Article
2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitor
Costales, Abran, Mathur, Michelle, Ramurthy, Savithri, Lan, Jiong, Subramanian, Sharadha, Jain, Rama, Atallah, Gordana, Setti, Lina, Lindvall, Mika, Appleton, Brent A., Ornelas, Elizabeth, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen E., Aronchik, Ida, Jefferson, Anne B., Shafer, Cynthia M.
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
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Journal Article
2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors
Costales, Abran, Mathur, Michelle, Ramurthy, Savithri, Lan, Jiong, Subramanian, Sharadha, Jain, Rama, Atallah, Gordana, Setti, Lina, Lindvall, Mika, Appleton, Brent A., Ornelas, Elizabeth, Feucht, Paul, Warne, Bob, Doyle, Laura, Basham, Stephen E., Aronchik, Ida, Jefferson, Anne B., Shafer, Cynthia M.
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
Published in Bioorganic & medicinal chemistry letters (15.03.2014)
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Journal Article
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors
Burger, Matthew T, Han, Wooseok, Lan, Jiong, Nishiguchi, Gisele, Bellamacina, Cornelia, Lindval, Mika, Atallah, Gordana, Ding, Yu, Mathur, Michelle, McBride, Chris, Beans, Elizabeth L, Muller, Kristine, Tamez, Victoriano, Zhang, Yanchen, Huh, Kay, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Holash, Jocelyn, Castillo, Joseph, Langowski, John, Wang, Yingyun, Chen, Min Y, Garcia, Pablo D
Published in ACS medicinal chemistry letters (12.12.2013)
Published in ACS medicinal chemistry letters (12.12.2013)
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Journal Article
브루톤 티로신 키나제의 억제제
CHEN WEI, ATALLAH GORDANA BABIC, JIA ZHAOZHONG J, POZZAN ALFONSO, RAVEGLIA LUCAL FRANCESCO, ZANALETTI RICCARDO
Year of Publication 05.03.2018
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Year of Publication 05.03.2018
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INHIBITORS OF BRUTONS TYROSINE KINASE
Jia, Zhaozhong J, Pozzan, Alfonso, Chen, Wei, Zanaletti, Riccardo, Raveglia, Luca F, Atallah, Gordana B
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Year of Publication 11.03.2021
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Inhibitors of Bruton's tyrosine kinase
Jia, Zhaozhong J, Pozzan, Alfonso, Raveglia, Lucal Francesco, Chen, Wei, Zanaletti, Riccardo, Atallah, Gordana Babic
Year of Publication 17.09.2020
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Year of Publication 17.09.2020
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INHIBITORS OF BRUTON'S TYROSINE KINASE
ZANALETTI, Riccardo, POZZAN, Alfonso, ATALLAH, Gordana, JIA, Zhaozhong, RAVEGLIA, Lucal, CHEN, Wei
Year of Publication 27.02.2020
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Year of Publication 27.02.2020
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INHIBITORS OF BRUTON'S TYROSINE KINASE
JIA, Zhaozhong, J, ZANALETTI, Riccardo, RAVEGLIA, Lucal, Francesco, POZZAN, Alfonso, ATALLAH, Gordana, Babic, CHEN, Wei
Year of Publication 16.01.2019
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Year of Publication 16.01.2019
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INHIBITEURS DE LA TYROSINE KINASE DE BRUTON
JIA, Zhaozhong, J, ZANALETTI, Riccardo, RAVEGLIA, Lucal, Francesco, POZZAN, Alfonso, ATALLAH, Gordana, Babic, CHEN, Wei
Year of Publication 20.06.2018
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Year of Publication 20.06.2018
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INHIBITORS OF BRUTON'S TYROSINE KINASE
JIA, Zhaozhong, J, ZANALETTI, Riccardo, RAVEGLIA, Lucal, Francesco, POZZAN, Alfonso, ATALLAH, Gordana, Babic, CHEN, Wei
Year of Publication 25.04.2018
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Year of Publication 25.04.2018
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Inhibitors of Bruton's tyrosine kinase
Jia, Zhaozhong J, Pozzan, Alfonso, Raveglia, Lucal Francesco, Chen, Wei, Zanaletti, Riccardo, Atallah, Gordana Babic
Year of Publication 07.12.2017
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Year of Publication 07.12.2017
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