Search Results - "ASPNES Gary E" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

2-((4-((S)-2--2-메틸벤조[d][1,3]디옥솔-4-일)피페리딘-1-일)메틸)-1-(((S)-옥세탄-2-일)메틸)-1H-벤조[d]이미다졸-6-카르복실산, 1,3-디히드록시-2-프로판-2-아민 염의 고체 형태

2-((4-((S)-2--2-메틸벤조[d][1,3]디옥솔-4-일)피페리딘-1-일)메틸)-1-(((S)-옥세탄-2-일)메틸)-1H-벤조[d]이미다졸-6-카르복실산, 1,3-디히드록시-2-프로판-2-아민 염의 고체 형태

by GRIFFITH DAVID ANDREW, BAGLEY SCOTT W, CURTO JOHN M, CLARK WESLEY DEWITT, LIAN YAJING, MATHIOWETZ ALAN M, ASPNES GARY E, LONDREGAN ALLYN T, PIOTROWSKI DAVID WALTER, EDMONDS DAVID JAMES, FUTATSUGI KENTARO, LIMBERAKIS CHRIS, RUGGERI ROGER B, FLANAGAN MARK E, HUARD KIM
Year of Publication 11.08.2022

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Patent

Regioselective Synthesis of 2 H -Indazoles Using a Mild, One-Pot Condensation–Cadogan Reductive Cyclization

Regioselective Synthesis of 2 H -Indazoles Using a Mild, One-Pot Condensation–Cadogan Reductive Cyclization

by Genung, Nathan E., Wei, Liuqing, Aspnes, Gary E.
Published in Organic letters (06.06.2014)

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Journal Article

ChemInform Abstract: Regioselective Synthesis of 2H-Indazoles Using a Mild, One-Pot Condensation-Cadogan Reductive Cyclization

ChemInform Abstract: Regioselective Synthesis of 2H-Indazoles Using a Mild, One-Pot Condensation-Cadogan Reductive Cyclization

by Genung, Nathan E., Wei, Liuqing, Aspnes, Gary E.
Published in ChemInform (09.12.2014)

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Journal Article

Novel syntheses of 3-anilino-pyrazin-2(1 H)-ones and 3-anilino-quinoxalin-2-(1 H)-ones via microwave-mediated Smiles rearrangement

Novel syntheses of 3-anilino-pyrazin-2(1 H)-ones and 3-anilino-quinoxalin-2-(1 H)-ones via microwave-mediated Smiles rearrangement

by Christopher Bi, F., Aspnes, Gary E., Guzman-Perez, Angel, Walker, Daniel P.
Published in Tetrahedron letters (10.03.2008)

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Journal Article

Corrigendum to “The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus” [Bioorg. Med. Chem. Lett. 22 (2012) 7100–7105]

Corrigendum to “The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of Type 2 diabetes mellitus” [Bioorg. Med. Chem. Lett. 22 (2012) 7100–7105]

by Pfefferkorn, Jeffrey A., Tu, Meihua, Filipski, Kevin J., Guzman-Perez, Angel, Bian, Jianwei, Aspnes, Gary E., Sammons, Matthew F., Song, Wei, Li, Jian-Cheng, Jones, Christopher S., Patel, Leena, Rasmusson, Tim, Zeng, Dongxiang, Karki, Kapil, Hamilton, Michael, Hank, Richard, Atkinson, Karen, Litchfield, John, Aiello, Robert, Baker, Levenia, Barucci, Nicole, Bourassa, Patricia, Bourbonais, Francis, D’Aquila, Theresa, Derksen, David R., MacDougall, Margit, Robertson, Alan
Published in Bioorganic & medicinal chemistry letters (01.09.2013)

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COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

by JIAO, WENHUA, CURTO, JOHN M, WIGLESWORTH, KRISTIN, FERNANDO, DILINIE, FLANAGAN, MARK E, LACASSE, SHAWN M, LIMBERAKIS, CHRIS, EDMONDS, DAVID JAMES, RUGGERI, ROGER B, MATHIOWETZ, ALAN M, PIOTROWSKI, DAVID WALTER, GRIFFITH, DAVID ANDREW, INGLE, GAJENDRA, LIAN, YAJING, ASPNES, GARY E, BAGLEY, SCOTT W, FUTATSUGI, KENTARO, LONDREGAN, ALLYN T, DOWLING, MATTHEW, HUARD, KIM
Year of Publication 18.06.2024

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Patent

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

by RUGGERI, Roger B, CLARK, Wesley Dewitt, LIAN, Yajing, ASPNES, Gary E, PIOTROWSKI, David Walter, HUARD, Kim, BAGLEY, Scott W, LONDREGAN, Allyn T, FLANAGAN, Mark E, GRIFFITH, David Andrew, MATHIOWETZ, Alan M, EDMONDS, David James, CURTO, John M, FUTATSUGI, Kentaro, LIMBERAKIS, Chris
Year of Publication 26.04.2023

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Patent

Solid Forms of 2-((4-((S)-2-(5-Chloropyridin-2-yl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-benzo[d]imidazole-6-carboxylic acid, 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine Salt

Solid Forms of 2-((4-((S)-2-(5-Chloropyridin-2-yl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-benzo[d]imidazole-6-carboxylic acid, 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine Salt

by Flanagan, Mark E, Mathiowetz, Alan M, Futatsugi, Kentaro, Huard, Kim, Curto, John M, Clark, Wesley Dewitt, Londregan, Allyn T, Bagley, Scott W, Edmonds, David James, Limberakis, Chris, Aspnes, Gary E, Griffith, David Andrew, Lian, Yajing, Ruggeri, Roger B, Piotrowski, David Walter
Year of Publication 09.02.2023

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SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

by RUGGERI, Roger B, CLARK, Wesley Dewitt, LIAN, Yajing, ASPNES, Gary E, PIOTROWSKI, David Walter, HUARD, Kim, BAGLEY, Scott W, LONDREGAN, Allyn T, FLANAGAN, Mark E, GRIFFITH, David Andrew, MATHIOWETZ, Alan M, EDMONDS, David James, CURTO, John M, FUTATSUGI, Kentaro, LIMBERAKIS, Chris
Year of Publication 19.10.2022

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Solid forms of 2-((4-((s)-2-(5-chloropyridin-2-yl)-2-methylbenzo(d) (1,3)dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-benzo(d) imidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-amine salt

Solid forms of 2-((4-((s)-2-(5-chloropyridin-2-yl)-2-methylbenzo(d) (1,3)dioxol-4-yl)piperidin-1-yl)methyl)-1-(((s)-oxetan-2-yl)methyl)-1h-benzo(d) imidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-amine salt

by RUGGERI, Roger B, CLARK, Wesley Dewitt, LIAN, Yajing, ASPNES, Gary E, PIOTROWSKI, David Walter, HUARD, Kim, BAGLEY, Scott W, LONDREGAN, Allyn T, FLANAGAN, Mark E, GRIFFITH, David Andrew, MATHIOWETZ, Alan M, EDMONDS, David James, CURTO, John M, FUTATSUGI, Kentaro, LIMBERAKIS, Chris
Year of Publication 16.06.2022

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Patent

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

by Flanagan, Mark E, Mathiowetz, Alan M, Wiglesworth, Kristin, Futatsugi, Kentaro, Huard, Kim, Ingle, Gajendra, LaCasse, Shawn M, Curto, John M, Londregan, Allyn T, Bagley, Scott W, Edmonds, David James, Limberakis, Chris, Fernando, Dilinie, Aspnes, Gary E, Griffith, David Andrew, Jiao, Wenhua, Lian, Yajing, Ruggeri, Roger B, Dowling, Matthew, Piotrowski, David Walter
Year of Publication 08.12.2022

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Patent

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

by CURTO, JOHN M, FLANAGAN, MARK E, LIMBERAKIS, CHRIS, EDMONDS, DAVID JAMES, RUGGERI, ROGER B, MATHIOWETZ, ALAN M, PIOTROWSKI, DAVID WALTER, GRIFFITH, DAVID ANDREW, LIAN, YAJING, ASPNES, GARY E, BAGLEY, SCOTT W, CLARK, WESLEY DEWITT, FUTATSUGI, KENTARO, LONDREGAN, ALLYN T, HUARD, KIM
Year of Publication 17.06.2021

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SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)METHYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

by RUGGERI, Roger B, CLARK, Wesley Dewitt, LIAN, Yajing, ASPNES, Gary E, PIOTROWSKI, David Walter, HUARD, Kim, BAGLEY, Scott W, LONDREGAN, Allyn T, FLANAGAN, Mark E, GRIFFITH, David Andrew, MATHIOWETZ, Alan M, EDMONDS, David James, CURTO, John M, FUTATSUGI, Kentaro, LIMBERAKIS, Chris
Year of Publication 17.06.2021

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Patent

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

by RUGGERI, Roger B, DOWLING, Matthew, LACASSE, Shawn M, INGLE, Gajendra, LIAN, Yajing, WIGLESWORTH, Kristin, JIAO, Wenhua, FERNANDO, Dilinie, ASPNES, Gary E, PIOTROWSKI, David Walter, HUARD, Kim, BAGLEY, Scott W, LONDREGAN, Allyn T, FLANAGAN, Mark E, GRIFFITH, David Andrew, MATHIOWETZ, Alan M, EDMONDS, David James, CURTO, John M, FUTATSUGI, Kentaro, LIMBERAKIS, Chris
Year of Publication 30.03.2022

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Patent

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES

by JIAO, WENHUA, CURTO, JOHN M, WIGLESWORTH, KRISTIN, FERNANDO, DILINIE, FLANAGAN, MARK E, LACASSE, SHAWN M, LIMBERAKIS, CHRIS, EDMONDS, DAVID JAMES, RUGGERI, ROGER B, MATHIOWETZ, ALAN M, PIOTROWSKI, DAVID WALTER, GRIFFITH, DAVID ANDREW, INGLE, GAJENDRA, LIAN, YAJING, ASPNES, GARY E, BAGLEY, SCOTT W, FUTATSUGI, KENTARO, LONDREGAN, ALLYN T, DOWLING, MATTHEW, HUARD, KIM
Year of Publication 26.11.2020

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Patent

FORMAS SÓLIDAS DE ÁCIDO 2-((4-((S)-2-(5-CLOROPIRIDIN-2-IL)-2-METILBENZO[D][1,3]DIOXOL-4-IL)PIPERIDIN-1-IL)METIL)-1-(((S)-OXETAN-2-IL)METIL)-1H-BENZO[D]IMIDAZOL-6-CARBOXÍLICO, SAL DE 1,3-DIHIDRÓXI-2-(HIDROXIMETIL)PROPAN-2-AMINA

FORMAS SÓLIDAS DE ÁCIDO 2-((4-((S)-2-(5-CLOROPIRIDIN-2-IL)-2-METILBENZO[D][1,3]DIOXOL-4-IL)PIPERIDIN-1-IL)METIL)-1-(((S)-OXETAN-2-IL)METIL)-1H-BENZO[D]IMIDAZOL-6-CARBOXÍLICO, SAL DE 1,3-DIHIDRÓXI-2-(HIDROXIMETIL)PROPAN-2-AMINA

by MARK E. FLANAGAN, ALAN M. MATHIOWETZ, JOHN M. CURTO, DAVID WALTER PIOTROWSKI, DAVID JAMES EDMONDS, KIM HUARD, ALLYN T. LONDREGAN, DAVID ANDREW GRIFFITH, CHRIS LIMBERAKIS, SCOTT W. BAGLEY, KENTARO FUTATSUGI, YAJING LIAN, GARY E. ASPNES, WESLEY DEWITT CLARK, ROGER B. RUGGERI
Year of Publication 16.08.2022

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Patent

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[ D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)ME THYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-((4-((S)-2-(5-CHLOROPYRIDIN-2-YL)-2-METHYLBENZO[ D] [1,3]DIOXOL-4-YL)PIPERIDIN-1-YL)METHYL)-1-(((S)-OXETAN-2-YL)ME THYL)-1H-BENZO[D] IMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

by RUGGERI Roger B, GRIFFITH David Andrew, FLANAGAN Mark E, HUARD Kim, CURTO John M, LIAN Yajing, LIMBERAKIS Chris, PIOTROWSKI David Walter, LONDREGAN Allyn T, BAGLEY Scott W, FUTATSUGI Kentaro, MATHIOWETZ Alan M, EDMONDS David James, ASPNES Gary E, CLARK Wesley Dewitt
Year of Publication 11.07.2022

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Patent

FORMAS SÓLIDAS DE SAL DE 1,3-DIHIDROXI-2-(HIDROXIMETIL)PROPAN-2-AMINA DE ÁCIDO 2-((4-((S)-2-(5-CLOROPIRIDIN-2-IL)-2-METILBENZO[D][1,3]DIOXOL-4-IL)PIPERIDIN-1-IL)METIL)-1-(((S)-OXETAN-2-IL)METIL)-1H-BENZO[D]IMIDAZOL-6-CARBOXÍLICO

FORMAS SÓLIDAS DE SAL DE 1,3-DIHIDROXI-2-(HIDROXIMETIL)PROPAN-2-AMINA DE ÁCIDO 2-((4-((S)-2-(5-CLOROPIRIDIN-2-IL)-2-METILBENZO[D][1,3]DIOXOL-4-IL)PIPERIDIN-1-IL)METIL)-1-(((S)-OXETAN-2-IL)METIL)-1H-BENZO[D]IMIDAZOL-6-CARBOXÍLICO

by CURTO, JOHN M, FLANAGAN, MARK E, LIMBERAKIS, CHRIS, EDMONDS, DAVID JAMES, RUGGERI, ROGER B, MATHIOWETZ, ALAN M, PIOTROWSKI, DAVID WALTER, GRIFFITH, DAVID ANDREW, LIAN, YAJING, ASPNES, GARY E, BAGLEY, SCOTT W, CLARK, WESLEY DEWITT, FUTATSUGI, KENTARO, LONDREGAN, ALLYN T, HUARD, KIM
Year of Publication 09.03.2022

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Patent

4-AMINO-5-OXO-7,8-DIHYDROPYRIMIDO[5,4-F][1,4]OXAZEPIN-6(5H)-YL PHENYL DERIVATIVES

4-AMINO-5-OXO-7,8-DIHYDROPYRIMIDO[5,4-F][1,4]OXAZEPIN-6(5H)-YL PHENYL DERIVATIVES

by DOW ROBERT L, ASPNES GARY E, MUNCHHOF MICHAEL J
Year of Publication 12.08.2010

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4-AMINO-7,8-DIHYDROPYRIDO[4,3-d]PYRIMIDIN-5(6H)-ONE DERIVATIVES

4-AMINO-7,8-DIHYDROPYRIDO[4,3-d]PYRIMIDIN-5(6H)-ONE DERIVATIVES

by DOW ROBERT L, ASPNES GARY E, MUNCHHOF MICHAEL J
Year of Publication 05.08.2010

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