Cross-Strand Pairing and Amyloid Assembly
Liang, Yan, Pingali, Sai Venkatesh, Jogalekar, Ashutosh S, Snyder, James P, Thiyagarajan, Pappannan, Lynn, David G
Published in Biochemistry (Easton) (23.09.2008)
Published in Biochemistry (Easton) (23.09.2008)
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Journal Article
The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity
ALI, Simak, HEATHCOTE, Dean A, TOLHURST, Robert S, KANNEGANTI, Seshu K, SNYDER, James P, LIOTTA, Dennis C, ABOAGYE, Eric O, BARRETT, Anthony G. M, COOMBES, R. Charles, KROLL, Sebastian H. B, JOGALEKAR, Ashutosh S, SCHEIPER, Bodo, PATEL, Hetal, BRACKOW, Jan, SIWICKA, Alekasandra, FUCHTER, Matthew J, PERIYASAMY, Manikandan
Published in Cancer research (Chicago, Ill.) (01.08.2009)
Published in Cancer research (Chicago, Ill.) (01.08.2009)
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Journal Article
A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration
Heathcote, Dean A, Patel, Hetal, Kroll, Sebastian H. B, Hazel, Pascale, Periyasamy, Manikandan, Alikian, Mary, Kanneganti, Seshu K, Jogalekar, Ashutosh S, Scheiper, Bodo, Barbazanges, Marion, Blum, Andreas, Brackow, Jan, Siwicka, Alekasandra, Pace, Robert D. M, Fuchter, Matthew J, Snyder, James P, Liotta, Dennis C, Freemont, Paul. S, Aboagye, Eric O, Coombes, R. Charles, Barrett, Anthony G. M, Ali, Simak
Published in Journal of medicinal chemistry (23.12.2010)
Published in Journal of medicinal chemistry (23.12.2010)
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Journal Article
Dictyostatin Flexibility Bridges Conformations in Solution and in the β-Tubulin Taxane Binding Site
Jogalekar, Ashutosh S, Damodaran, Krishnan, Kriel, Frederik H, Jung, Won-Hyuk, Alcaraz, Ana A, Zhong, Shi, Curran, Dennis P, Snyder, James P
Published in Journal of the American Chemical Society (02.03.2011)
Published in Journal of the American Chemical Society (02.03.2011)
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Journal Article
The Discodermolide Hairpin Structure Flows from Conformationally Stable Modular Motifs
Jogalekar, Ashutosh S, Kriel, Frederik H, Shi, Qi, Cornett, Ben, Cicero, Daniel, Snyder, James P
Published in Journal of medicinal chemistry (14.01.2010)
Published in Journal of medicinal chemistry (14.01.2010)
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Journal Article
Abstract 4878: RMC-4550, an allosteric inhibitor of SHP2: Synthesis, structure, and anti-tumor activity
Koltun, Elena S., Aay, Naing, Buckl, Andreas, Jogalekar, Ashutosh S., Kiss, Gert, Marquez, Abby, Mellem, Kevin T., Mordec, Kasia, Saldajeno-Concar, Mae, Semko, Chris M., Tibrewal, Nidhi, Tzitzilonis, Christos, Won, Walter, Smith, Jacqueline A., Wilson, Susan E., Nichols, Robert J., Wang, Zhengping, Wilds, David, Singh, Mallika, Gill, Adrian L.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 4877: Allosteric inhibition of SHP2 variants containing cancer-associated activating mutations
Wildes, David, Aay, Naing, Buckl, Andreas, Hsieh, Daphne, Jogalekar, Ashutosh S., Kiss, Gert, Koltun, Elena S., Marquez, Abby, Mellem, Kevin T., Romero, Jason, Saldajeno-Concar, Mae, Schulze, Christopher J., Semko, Chris M., Won, Walter, Nichols, Robert J., Stahlhut, Carlos, Tzitzilonis, Christos, Gill, Adrian L., Smith, Jacqueline A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
The development of a selective cyclin-dependent kinase inhibitor which demonstrates anti-tumor activity
Ali, Simak, Heathcote, Dean A., Kroll, Sebastian H. B., Jogalekar, Ashutosh S., Scheiper, Bodo, Patel, Hetal, Brackow, Jan, Siwicka, Alekasandra, Fuchter, Matthew J., Periyasamy, Manikandan, Tolhurst, Robert S., Kanneganti, Seshu K., Snyder, James P., Liotta, Dennis C., Aboagye, Eric O., Barrett, Anthony G. M., Coombes, R. Charles
Published in Cancer research (Chicago, Ill.) (28.07.2009)
Published in Cancer research (Chicago, Ill.) (28.07.2009)
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Journal Article
2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS
KISS, Gert, JOGALEKAR, Ashutosh, GILL, Adrian, MELLEM, Kevin, SEMKO, Christopher, AAY, Naing, WON, Walter, BUCKL, Andreas, KOLTUN, Elena S
Year of Publication 11.04.2024
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Year of Publication 11.04.2024
Patent
2,5-DISUBSTITUTED 3-METHYL PYRAZINES AND 2,5,6-TRISUBSTITUTED 3-METHYL PYRAZINES AS ALLOSTERIC SHP2 INHIBITORS
JOGALEKAR, Ashutosh, KISS, Gert, GILL, Adrian, MELLEM, Kevin, AAY, Naing, SEMKO, Christopher, WON, Walter, BUCKL, Andreas, KOLTUN, Elena S
Year of Publication 15.11.2023
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Year of Publication 15.11.2023
Patent