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Taylor, Rod S, Ashton, Kate E, Moxham, Tiffany, Hooper, Lee, Ebrahim, Shah
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Published in Cochrane database of systematic reviews (06.07.2011)
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Methods of assessment of selenium status in humans: a systematic review
ASHTON, Kate, HOOPER, Lee, HARVEY, Linda J, HURST, Rachel, CASGRAIN, Amélie, FAIRWEATHER-TAIT, Susan J
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Published in The American journal of clinical nutrition (01.06.2009)
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Strategies to address recruitment to a randomised trial of surgical and non-surgical treatment for cancer: results from a complex recruitment intervention within the Mesothelioma and Radical Surgery 2 (MARS 2) study
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Published in Journal of medicinal chemistry (24.03.2022)
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Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors
Lloyd, David J., St Jean, David J., Kurzeja, Robert J. M., Wahl, Robert C., Michelsen, Klaus, Cupples, Rod, Chen, Michelle, Wu, John, Sivits, Glenn, Helmering, Joan, Komorowski, Renée, Ashton, Kate S., Pennington, Lewis D., Fotsch, Christopher, Vazir, Mukta, Chen, Kui, Chmait, Samer, Zhang, Jiandong, Liu, Longbin, Norman, Mark H., Andrews, Kristin L., Bartberger, Michael D., Van, Gwyneth, Galbreath, Elizabeth J., Vonderfecht, Steven L., Wang, Minghan, Jordan, Steven R., Véniant, Murielle M., Hale, Clarence
Published in Nature (London) (01.12.2013)
Published in Nature (London) (01.12.2013)
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Effectiveness and cost-effectiveness of radiofrequency denervation versus placebo for chronic and moderate to severe low back pain: study protocol for the RADICAL randomised controlled trial
Ashton, Kate E, Price, Cathy, Fleming, Leah, Blom, Ashley W, Culliford, Lucy, Evans, Rebecca Nicole, Foster, Nadine E, Hollingworth, William, Jameson, Catherine, Jeynes, Nouf, Moore, Andrew J, Orpen, Neil, Palmer, Cecily, Reeves, Barnaby C, Rogers, Chris A, Wylde, Vikki
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Published in BMJ open (27.07.2024)
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 3. Structure–Activity Relationships within the Aryl Carbinol Region of the N‑Arylsulfonamido‑N′‑arylpiperazine Series
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Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Nonracemic Synthesis of GK–GKRP Disruptor AMG-3969
Bourbeau, Matthew P, Ashton, Kate S, Yan, Jie, St. Jean, David J
Published in Journal of organic chemistry (18.04.2014)
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Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase–Glucokinase Regulatory Protein (GK–GKRP) Binding: Strategic Use of a N → S (nN → σS–X) Interaction for Conformational Constraint
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Published in Journal of medicinal chemistry (24.12.2015)
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept
Ashton, Kate S., Andrews, Kristin L., Bryan, Marion C., Chen, Jie, Chen, Kui, Chen, Michelle, Chmait, Samer, Croghan, Michael, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Jordan, Steve R., Kurzeja, Robert J. M., Michelsen, Klaus, Pennington, Lewis D., Poon, Steve F., Sivits, Glenn, Van, Gwyneth, Vonderfecht, Steve L., Wahl, Robert C., Zhang, Jiandong, Lloyd, David J., Hale, Clarence, St. Jean, David J.
Published in Journal of medicinal chemistry (23.01.2014)
Published in Journal of medicinal chemistry (23.01.2014)
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Discovery of a Covalent Inhibitor of KRAS G12C (AMG 510) for the Treatment of Solid Tumors
Lanman, Brian A, Allen, Jennifer R, Allen, John G, Amegadzie, Albert K, Ashton, Kate S, Booker, Shon K, Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J, Goodman, Guy, Kopecky, David J, Liu, Longbin, Lopez, Patricia, Low, Jonathan D, Ma, Vu, Minatti, Ana E, Nguyen, Thomas T, Nishimura, Nobuko, Pickrell, Alexander J, Reed, Anthony B, Shin, Youngsook, Siegmund, Aaron C, Tamayo, Nuria A, Tegley, Christopher M, Walton, Mary C, Wang, Hui-Ling, Wurz, Ryan P, Xue, May, Yang, Kevin C, Achanta, Pragathi, Bartberger, Michael D, Canon, Jude, Hollis, L Steven, McCarter, John D, Mohr, Christopher, Rex, Karen, Saiki, Anne Y, San Miguel, Tisha, Volak, Laurie P, Wang, Kevin H, Whittington, Douglas A, Zech, Stephan G, Lipford, J Russell, Cee, Victor J
Published in Journal of medicinal chemistry (09.01.2020)
Published in Journal of medicinal chemistry (09.01.2020)
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 2. Leveraging Structure-Based Drug Design to Identify Analogues with Improved Pharmacokinetic Profiles
St. Jean, David J., Ashton, Kate S., Bartberger, Michael D., Chen, Jie, Chmait, Samer, Cupples, Rod, Galbreath, Elizabeth, Helmering, Joan, Hong, Fang-Tsao, Jordan, Steven R., Liu, Longbin, Kunz, Roxanne K., Michelsen, Klaus, Nishimura, Nobuko, Pennington, Lewis D., Poon, Steve F., Reid, Darren, Sivits, Glenn, Stec, Markian M., Tadesse, Seifu, Tamayo, Nuria, Van, Gwyneth, Yang, Kevin C., Zhang, Jiandong, Norman, Mark H., Fotsch, Christopher, Lloyd, David J., Hale, Clarence
Published in Journal of medicinal chemistry (23.01.2014)
Published in Journal of medicinal chemistry (23.01.2014)
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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 4. Exploration of a Novel Binding Pocket
Hong, Fang-Tsao, Norman, Mark H, Ashton, Kate S, Bartberger, Michael D, Chen, Jie, Chmait, Samer, Cupples, Rod, Fotsch, Christopher, Jordan, Steven R, Lloyd, David J, Sivits, Glenn, Tadesse, Seifu, Hale, Clarence, St. Jean, David J
Published in Journal of medicinal chemistry (24.07.2014)
Published in Journal of medicinal chemistry (24.07.2014)
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Correction to Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept
Ashton, Kate S, Andrews, Kristin L, Bryan, Marian C, Chen, Jie, Chen, Kui, Chen, Michelle, Chmait, Samer, Croghan, Michael, Cupples, Rod, Fotsch, Christopher, Helmering, Joan, Jordan, Steve R, Kurzeja, Robert J. M, Michelsen, Klaus, Pennington, Lewis D, Poon, Steve F, Sivits, Glenn, Van, Gwyneth, Vonderfecht, Steve L, Wahl, Robert C, Zhang, Jiandong, Lloyd, David J, Hale, Clarence, St. Jean, David J
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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