Efficacy and safety of an anti–IL-13 mAb in patients with severe asthma: A randomized trial
De Boever, Erika H., PhD, Ashman, Claire, BSc, Cahn, Anthony P., MB BS, Locantore, Nicholas W., PhD, Overend, Phil, BSc (Hons), Pouliquen, Isabelle J., PharmD, Serone, Adrian P., PhD, Wright, Tracey J., PhD, Jenkins, Mair M., MB BS, Panesar, Inderpal S., MRPharmS, Thiagarajah, Sivayogan S., MB ChB, Wenzel, Sally E., MD
Published in Journal of allergy and clinical immunology (01.04.2014)
Published in Journal of allergy and clinical immunology (01.04.2014)
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Journal Article
A phase 1, randomized, placebo‐controlled, dose‐escalation study of an anti‐IL‐13 monoclonal antibody in healthy subjects and mild asthmatics
Hodsman, Peter, Ashman, Claire, Cahn, Anthony, De Boever, Erika, Locantore, Nicholas, Serone, Adrian, Pouliquen, Isabelle
Published in British journal of clinical pharmacology (01.01.2013)
Published in British journal of clinical pharmacology (01.01.2013)
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Journal Article
'In-Format' screening of a novel bispecific antibody format reveals significant potency improvements relative to unformatted molecules
Scott, Martin J, Lee, Jennifer A, Wake, Matthew S, Batt, Kelly V, Wattam, Trevor A, Hiles, Ian D, Batuwangala, Thil D, Ashman, Claire I, Steward, Michael
Published in mAbs (01.01.2017)
Published in mAbs (01.01.2017)
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Journal Article
MODIFIED PROTEINS AND PEPTIDES
ASHMAN CLAIRE, MORLEY PETER, SANDAL THOMAS, BIRCHLER MARY, DE WILDT RUDOLF M T, LEWIS ALAN PETER, HOLLAND CLAIRE, STEWARD MICHAEL
Year of Publication 08.10.2019
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Year of Publication 08.10.2019
Patent
ANTI-VEGF SINGLE VARIABLE DOMAINS FUSED TO FC DOMAINS
ASHMAN CLAIRE, HUGHES THOMAS ZOE, LEWIS ALAN PETER, CATCHPOLE IAN RICHARD, STEWARD MICHAEL
Year of Publication 04.04.2014
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Year of Publication 04.04.2014
Patent
IL-13 BINDING PROTEIN
ASHMAN CLAIRE, ELLIS JONATHAN HENRY, ORECCHIA MARTIN ANIBAL, LEWIS ALAN PETER, HAMBLIN PAUL ANDREW
Year of Publication 12.04.2012
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Year of Publication 12.04.2012
Patent
Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR down-modulation
Bell, I, Ashman, C, Maughan, J, Hooker, E, Cook, F, Reinhart, TA
Published in Journal of general virology (01.11.1998)
Published in Journal of general virology (01.11.1998)
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MODIFIED PROTEINS AND PEPTIDES
ASHMAN CLAIRE, MORLEY PETER, SANDAL THOMAS, BIRCHLER MARY, DE WILDT RUDOLF M T, LEWIS ALAN PETER, HOLLAND CLAIRE, STEWARD MICHAEL
Year of Publication 08.05.2014
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Year of Publication 08.05.2014
Patent
GRID: A Novel Grb-2-Related Adapter Protein That Interacts with the Activated T Cell Costimulatory Receptor CD28
Ellis, Jonathan H, Ashman, Claire, Burden, M. Neil, Kilpatrick, Katherine E, Morse, Mary A, Hamblin, Paul A
Published in The Journal of immunology (1950) (01.06.2000)
Published in The Journal of immunology (1950) (01.06.2000)
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The Conserved Process of TCR/CD3 Complex Down-Modulation by SIV Nef Is Mediated by the Central Core, Not Endocytic Motifs
Schaefer, Todd M, Bell, Ian, Pfeifer, Melanie E., Ghosh, Mimi, Trible, Ronald P., Fuller, Craig L., Ashman, Claire, Reinhart, Todd A.
Published in Virology (New York, N.Y.) (10.10.2002)
Published in Virology (New York, N.Y.) (10.10.2002)
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Journal Article
MYOSTATIN BINDING PROTEINS
WILSON PAUL, ELLIS JONATHAN HENRY, ZHANG HONG, KIRBY IAN, SHEN YING, LEWIS ALAN, ORECCHIA MARTIN ANIBAL, XU TIAN SHUN, ASHMAN CLAIRE, KULL FREDERICK, HAN BAJIN, LINDLEY KATHRYN MASON, BEATON ANDREW
Year of Publication 20.09.2011
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Year of Publication 20.09.2011
Patent
ANTIGEN-BINDING CONSTRUCTS
CLEGG STEPHANIE JANE, HUSSAIN FARHANA, ELLIS JONATHAN HENRY, BATUWANGALA THIL, LEWIS ALAN, ORECCHIA MARTIN ANIBAL, JESPERS LAURENT, HAMBLIN PAUL ANDREW, STEWARD MICHAEL, ASHMAN CLAIRE, BURDEN MICHAEL NEIL, SHAH RADHA, DE WILDT RUDOLF MARIA
Year of Publication 03.09.2010
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Year of Publication 03.09.2010
Patent
USE OF TNF-ALPHA BINDING PROTEINS AND IL-7 BINDING PROTEINS IN MEDICAL TREATMENT
SOKOLOVE, Jeremy, NAGPAL, Sunil, MORLEY, Peter Joseph, TOCKER, Joel, COULSTOCK, Edward Thomas, HOPLEY, Stephanie, LICH, John, TICKLE, Joseph R, LEWIS, Alan Peter, ASHMAN, Claire, BOUMA, Gerben, NEISEN, Jessica Lynn, DIXON, David, RYCROFT, Daniel
Year of Publication 30.11.2023
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Year of Publication 30.11.2023
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MODIFIED PROTEINS AND PEPTIDES
Ashman, Claire, Morley, Peter, Lewis, Alan Peter, Birchler, Mary, De Wildt, Rudolf M.T, Holland, Claire, Sandal, Thomas, Steward, Michael
Year of Publication 21.01.2021
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Year of Publication 21.01.2021
Patent
Modified proteins and peptides
Ashman, Claire, Morley, Peter, Lewis, Alan Peter, Birchler, Mary, Holland, Claire, Sandal, Thomas, Steward, Michael, De Wildt, Rudolf M. T
Year of Publication 20.10.2020
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Year of Publication 20.10.2020
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MODIFIED PROTEINS AND PEPTIDES
SANDAL, Thomas, HOLLAND, Claire, LEWIS, Alan Peter, STEWARD, Michael, ASHMAN, Claire, BIRCHLER, Mary, DE WILDT, Rudolf M T, MORLEY, Peter
Year of Publication 24.06.2020
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Year of Publication 24.06.2020
Patent
MODIFIED PROTEINS AND PEPTIDES
Ashman, Claire, Morley, Peter, De Wildt, Rudolf M T, Lewis, Alan Peter, Birchler, Mary, Holland, Claire, Sandal, Thomas, Steward, Michael
Year of Publication 28.03.2019
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Year of Publication 28.03.2019
Patent
MODIFIED PROTEINS AND PEPTIDES
Ashman, Claire, Morley, Peter, Lewis, Alan Peter, Birchler, Mary, Holland, Claire, Sandal, Thomas, Steward, Michael, De Wildt, Rudolf M. T
Year of Publication 28.03.2019
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Year of Publication 28.03.2019
Patent
construto e proteína aglutinantes ao antígeno, dímero, composição farmacêutica, sequência de polinucleotídeo, célula hospedeira e, método para produção do construto
ALAN PETER LEWIS, ZOE HUGHES-THOMAS, IAN RICHARD CATCHPOLE, MICHAEL STEWARD, CLAIRE ASHMAN
Year of Publication 21.02.2017
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Year of Publication 21.02.2017
Patent