Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors
Ganguly, Ashit K, Alluri, Sesha S, Caroccia, Danielle, Biswas, Dipshikha, Wang, Chih-Hung, Kang, Eunhee, Zhang, Yong, McPhail, Andrew T, Carroll, Steven S, Burlein, Christine, Munshi, Vandna, Orth, Peter, Strickland, Corey
Published in Journal of medicinal chemistry (27.10.2011)
Published in Journal of medicinal chemistry (27.10.2011)
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Structural optimization of cyclic sulfonamide based novel HIV-1 protease inhibitors to picomolar affinities guided by X-ray crystallographic analysis
Ganguly, Ashit K., Alluri, Sesha S., Wang, Chih-Hung, Antropow, Alyssa, White, Alex, Caroccia, Danielle, Biswas, Dipshikha, Kang, Eunhee, Zhang, Li-Kang, Carroll, Steven S., Burlein, Christine, Fay, John, Orth, Peter, Strickland, Corey
Published in Tetrahedron (06.05.2014)
Published in Tetrahedron (06.05.2014)
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Total Synthesis of (−)-Himgaline
Shah, Unmesh, Chackalamannil, Samuel, Ganguly, Ashit K, Chelliah, Mariappan, Kolotuchin, Sergei, Buevich, Alexei, McPhail, Andrew
Published in Journal of the American Chemical Society (04.10.2006)
Published in Journal of the American Chemical Society (04.10.2006)
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Journal Article
2-Phenylimidazo[1,2- b]pyridazine derivatives highly active against Haemonchus contortus
Ali, Abdelselam, Cablewski, Teresa, Francis, Craig L., Ganguly, Ashit K., Sargent, Roger M., Sawutz, David G., Winzenberg, Kevin N.
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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Journal Article
Mass spectrometric detection of the noncovalent GDP-bound conformational state of the human H-ras protein
Ganguly, Ashit K, Pramanik, Birendra N, Tsarbopoulos, Anthony, Covey, Thomas R, Huang, Eric, Fuhrman, Shella A
Published in Journal of the American Chemical Society (01.07.1992)
Published in Journal of the American Chemical Society (01.07.1992)
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Concise asymmetric routes to 2,2,4-trisubstituted tetrahydrofurans via chiral titanium imide enolates: Key intermediates towards synthesis of highly active azole antifungals SCH 51048 and SCH 56592
Saksena, Anil K, Girijavallabhan, Viyyoor M, Wang, Haiyan, Liu, Yi-Tsung, Pike, Russel E, Ganguly, Ashit K
Published in Tetrahedron letters (05.08.1996)
Published in Tetrahedron letters (05.08.1996)
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Journal Article
Correction to Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors
Ganguly, Ashit K, Alluri, Sesha S, Caroccia, Danielle, Biswas, Dipshikha, Wang, Chih-Hung, Kang, Eunhee, Zhang, Yong, McPhail, Andrew T, Carroll, Steven S, Burlein, Christine, Munshi, Vandna, Orth, Peter, Strickland, Corey
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Journal Article
Surfing the piperazine core of tricyclic farnesyltransferase inhibitors
Rokosz, Laura L., Huang, Chia-Yu, Reader, John C., Stauffer, Tara M., Chelsky, Daniel, Sigal, Nolan H., Ganguly, Ashit K., Baldwin, John J.
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
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Journal Article
Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048)
Nomeir, Amin A, Pramanik, Birendra N, Heimark, Larry, Bennett, Frank, Veals, John, Bartner, Peter, Hilbert, Maryjane, Saksena, Anil, McNamara, Paul, Girijavallabhan, Viyyoor, Ganguly, Ashit K, Lovey, Raymond, Pike, Russell, Wang, Haiyan, Liu, Yi-Tsung, Kumari, Pramila, Korfmacher, Walter, Lin, Chin-Chung, Cacciapuoti, Anthony, Loebenberg, David, Hare, Roberta, Miller, George, Pickett, Cecil
Published in Journal of mass spectrometry. (01.04.2008)
Published in Journal of mass spectrometry. (01.04.2008)
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Mass spectrometric studies of potent inhibitors of farnesyl protein transferase--detection of pentameric noncovalent complexes
Mirza, Urooj A, Chen, Guodong, Liu, Yan-Hui, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K, Pramanik, Birendra N
Published in Journal of mass spectrometry. (01.10.2008)
Published in Journal of mass spectrometry. (01.10.2008)
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Journal Article
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 ( 1), and the discovery of posaconazole [Sch 56592; 2 or ( S, S)- 5]
Bennett, Frank, Saksena, Anil K., Lovey, Raymond G., Liu, Yi-Tsung, Patel, Naginbhai M., Pinto, Patrick, Pike, Russel, Jao, Edwin, Girijavallabhan, Viyyoor M., Ganguly, Ashit K., Loebenberg, David, Wang, Haiyan, Cacciapuoti, Anthony, Moss, Eugene, Menzel, Fred, Hare, Roberta S., Nomeir, Amin
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Structure elucidation of everninomicin-6, a new oligosaccharide antibiotic, by chemical degradation and FAB-MS methods
Bartner, Peter, Pramanik, Birendra N., Saksena, Anil K., Liu, Yan-Hui, Das, Pradip R., Sarre, Olga, Ganguly, Ashit K.
Published in Journal of the American Society for Mass Spectrometry (01.11.1997)
Published in Journal of the American Society for Mass Spectrometry (01.11.1997)
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Journal Article
Conference Proceeding
(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336): A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent
Njoroge, F. George, Taveras, Arthur G, Kelly, Joseph, Remiszewski, Stacy, Mallams, Alan K, Wolin, Ronald, Afonso, Adriano, Cooper, Alan B, Rane, Dinananth F, Liu, Yi-Tsung, Wong, Jesse, Vibulbhan, Bancha, Pinto, Patrick, Deskus, Jeffrey, Alvarez, Carmen S, del Rosario, Joycelyn, Connolly, Michael, Wang, James, Desai, Jagdish, Rossman, Randall R, Bishop, W. Robert, Patton, Robert, Wang, Lynn, Kirschmeier, Paul, Bryant, Mathew S, Nomeir, Amin A, Lin, C.-C, Liu, Ming, McPhail, Andrew T, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K
Published in Journal of medicinal chemistry (19.11.1998)
Published in Journal of medicinal chemistry (19.11.1998)
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Guiding farnesyltransferase inhibitors from an ECLiPS ® library to the catalytic zinc
Huang, Chia-Yu, Stauffer, Tara M., Strickland, Corey L., Reader, John C., Huang, He, Li, Ge, Cooper, Alan B., Doll, Ronald J., Ganguly, Ashit K., Baldwin, John J., Rokosz, Laura L.
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Tricyclic Farnesyl Protein Transferase Inhibitors: Crystallographic and Calorimetric Studies of Structure−Activity Relationships
Strickland, Corey L, Weber, Patricia C, Windsor, William T, Wu, Zhen, Le, Hung V, Albanese, Margaret M, Alvarez, Carmen S, Cesarz, David, del Rosario, Joycelyn, Deskus, Jeffrey, Mallams, Alan K, Njoroge, F. George, Piwinski, John J, Remiszewski, Stacy, Rossman, Randall R, Taveras, Arthur G, Vibulbhan, Bancha, Doll, Ronald J, Girijavallabhan, Viyyoor M, Ganguly, Ashit K
Published in Journal of medicinal chemistry (17.06.1999)
Published in Journal of medicinal chemistry (17.06.1999)
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Journal Article
Structural Characterization of the Oligosaccharide Antibiotics Everninomicins by Negative Ion FAB and ESI/MS
PRAMANIK, BIRENDRA N., SHIPKOVA, PETIA A., BARTNER, PETER L., HEIMARK, LARRY, LIU, YAN-HUI, DAS, PRADIP R., SAKSENA, ANIL K., SARRE, OLGA Z., GIRIJAVALLABHAN, VIYYOR M., GANGULY, ASHIT K.
Published in Journal of antibiotics (2000)
Published in Journal of antibiotics (2000)
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Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor
Billah, M Motasim, Cooper, Nicola, Minnicozzi, Michael, Warneck, Julie, Wang, Peng, Hey, John A, Kreutner, William, Rizzo, Charles A, Smith, Sidney R, Young, Simon, Chapman, Richard W, Dyke, Hazel, Shih, Nang-Yang, Piwinski, John J, Cuss, Francis M, Montana, John, Ganguly, Ashit K, Egan, Robert W
Published in The Journal of pharmacology and experimental therapeutics (01.07.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2002)
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