Preparation and Pharmacological Evaluation of Novel Glycoprotein (Gp) IIb/IIIa Antagonists. 1. The Selection of Naphthalene Derivatives
ONO, Shin'ichiro, INOUE, Yoshihisa, YOSHIDA, Tomohiro, ASHIMORI, Atsuyuki, KOSAKA, Keigo, IMADA, Teruaki, FUKAYA, Chikara, NAKAMURA, Norifumi
Published in Chemical & pharmaceutical bulletin (1999)
Published in Chemical & pharmaceutical bulletin (1999)
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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Investigations of Intramolecular Heck Reactions of (E)-α,β-Unsaturated 2-Haloanilides and Analogues To Form Enantioenriched Spirocyclic Products
Ashimori, Atsuyuki, Bachand, Benoit, Overman, Larry E, Poon, Daniel J
Published in Journal of the American Chemical Society (08.07.1998)
Published in Journal of the American Chemical Society (08.07.1998)
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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)-α,β-Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates
Ashimori, Atsuyuki, Bachand, Benoit, Calter, Michael A, Govek, Steven P, Overman, Larry E, Poon, Daniel J
Published in Journal of the American Chemical Society (08.07.1998)
Published in Journal of the American Chemical Society (08.07.1998)
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Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W‐212393 in rats
Teshima, Koji, Minoguchi, Masanori, Tounai, Sayuri, Ashimori, Atsuyuki, Eguchi, Junichi, Allen, Charles N, Shibata, Shigenobu
Published in British journal of pharmacology (01.09.2005)
Published in British journal of pharmacology (01.09.2005)
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Synthesis and pharmacological effects of optically active 2-(4-(4-benzhydryl-1-piperazinyl)phenyl)-ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate hydrochloride
ASHIMORI, Atsuyuki, UCHIDA, Takeshi, OHTAKI, Yutaka, TANAKA, Mikio, OHE, Kazuhito, FUKAYA, Chikara, WATANABE, Masahiro, KAGITANI, Masao, YOKOYAMA, Kazumasa
Published in Chemical & pharmaceutical bulletin (1991)
Published in Chemical & pharmaceutical bulletin (1991)
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Novel 1, 4-Dihydropyridine Calcium Antagonists. I. : Synthesis and Hypotensive Activity of 4-(Substituted Pyridyl)-1, 4-dihydropyridine Derivatives
ASHIMORI, Atsuyuki, ONO, Taizo, UCHIDA, Takeshi, OHTAKI, Yutaka, FUKAYA, Chikara, WATANABE, Masahiro, YOKOYAMA, Kazumasa
Published in Chemical & pharmaceutical bulletin (1990)
Published in Chemical & pharmaceutical bulletin (1990)
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Catalytic asymmetric synthesis of either enantiomer of physostigmine. Formation of quaternary carbon centers with high enantioselection by intramolecular Heck reactions of (Z)-2-butenanilides
Ashimori, Atsuyuki, Matsuura, Takaharu, Overman, Larry E, Poon, Daniel J
Published in Journal of organic chemistry (01.12.1993)
Published in Journal of organic chemistry (01.12.1993)
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Novel 1,4-dihydropyridine calcium antagonists. II. Synthesis and antihypertensive activity of 3-(4-(substituted amino)phenylalkyl)ester derivatives
ASHIMORI, Atsuyuki, ONO, Taizo, INOUE, Yoshihisa, MORIMOTO, Satoshi, EDA, Masahiro, UCHIDA, Takeshi, OHTAKI, Yutaka, FUJINO, Yoshiyuki, KIDO, Hideaki, OGURA, Yasushi, FUKAYA, Chikara, WATANABE, Masahiro, YOKOYAMA, Kazumasa
Published in Chemical & pharmaceutical bulletin (1991)
Published in Chemical & pharmaceutical bulletin (1991)
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Synthesis, Structure−Activity Relationships, and Pharmacokinetic Profiles of Nonpeptidic Difluoromethylene Ketones as Novel Inhibitors of Human Chymase
Akahoshi, Fumihiko, Ashimori, Atsuyuki, Sakashita, Hiroshi, Yoshimura, Takuya, Eda, Masahiro, Imada, Teruaki, Nakajima, Masahide, Mitsutomi, Naoko, Kuwahara, Shigeki, Ohtsuka, Tatsuyuki, Fukaya, Chikara, Miyazaki, Mizuo, Nakamura, Norifumi
Published in Journal of medicinal chemistry (12.04.2001)
Published in Journal of medicinal chemistry (12.04.2001)
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Synthesis, Structure−Activity Relationships, and Pharmacokinetic Profiles of Nonpeptidic α-Keto Heterocycles as Novel Inhibitors of Human Chymase
Akahoshi, Fumihiko, Ashimori, Atsuyuki, Sakashita, Hiroshi, Yoshimura, Takuya, Imada, Teruaki, Nakajima, Masahide, Mitsutomi, Naoko, Kuwahara, Shigeki, Ohtsuka, Tatsuyuki, Fukaya, Chikara, Miyazaki, Mizuo, Nakamura, Norifumi
Published in Journal of medicinal chemistry (12.04.2001)
Published in Journal of medicinal chemistry (12.04.2001)
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Non-peptidic inhibitors of human chymase. synthesis, structure-activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones
AKAHOSHI, Fumihiko, ASHIMORI, Atsuyuki, NAKAMURA, Norifumi, YOSHIMURA, Takuya, IMADA, Teruaki, NAKAJIMA, Masahide, MITSUTOMI, Naoko, KUWAHARA, Shigeki, OHTSUKA, Tatsuyuki, FUKAYA, Chikara, MIYAZAKI, Mizuo
Published in Bioorganic & medicinal chemistry (01.02.2001)
Published in Bioorganic & medicinal chemistry (01.02.2001)
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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Investigations of Intramolecular Heck Reactions of (E)-α,β-Unsaturated 2-Haloanilides and Analogs To Form Enantioenriched Spirocyclic Products. [J. Am. Chem. Soc. 1998, 120, 6477−6487]
Ashimori, Atsuyuki, Bachand, Benoit, Overman, Larry E
Published in Journal of the American Chemical Society (12.01.2000)
Published in Journal of the American Chemical Society (12.01.2000)
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NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USES THEREOF
SAKASHITA, HIROSHI, EDA, MASAHIRO, AKAHOSHI, FUMIHIKO, ASHIMORI, ATSUYUKI, YOSHIMURA, TAKUYA, NAKAJIMA, MASAHIDE, IMADA, TERUAKI
Year of Publication 07.05.1998
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Year of Publication 07.05.1998
Patent
Peptidyl human heart chymase inhibitors. 2. Discovery of highly selective difluoromethylene ketone derivatives with Glu AT P3 site
Eda, Masahiro, Ashimori, Atsuyuki, Akahoshi, Fumihiko, Yoshimura, Takuya, Inoue, Yoshihisa, Fukaya, Chikara, Nakajima, Masahide, Fukuyama, Hajime, Imada, Teruaki, Nakamura, Norifumi
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
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Peptidyl human heart chymase inhibitors. 1. Synthesis and inhibitory activity of difluoromethylene ketone derivatives bearing P′ binding subsites
Eda, Masahiro, Ashimori, Atsuyuki, Akahoshi, Fumihiko, Yoshimura, Takuya, Inoue, Yoshihisa, Fukaya, Chikara, Nakajima, Masahide, Fukuyama, Hajime, Imada, Teruaki, Nakamura, Norifumi
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
Published in Bioorganic & medicinal chemistry letters (21.04.1998)
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CHYMASE INHIBITORS
SAKASHITA, HIROSHI, EDA, MASAHIRO, AKAHOSHI, FUMIHIKO, OOTSUKA, TATSUYUKI, TANAKA, MIKIO, ASHIMORI, ATSUYUKI, YOSHIMURA, TAKUYA, FUKUYAMA, HAJIME, NAKAJIMA, MASAHIDE, IMADA, TERUAKI
Year of Publication 01.07.1999
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Year of Publication 01.07.1999
Patent
HETEROCYCLIC AMIDE COMPOUNDS AND MEDICINAL USE OF THE SAME
EDA, MASAHIRO, AKAHOSHI, FUMIHIKO, OKUNISHI, HIDEKI, ASHIMORI, ATSUYUKI, YOSHIMURA, TAKUYA, FUKUYAMA, HAJIME, NAKAJIMA, MASAHIDE, IMADA, TERUAKI, MIYAZAKI, MIZUO
Year of Publication 31.10.1996
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Year of Publication 31.10.1996
Patent
Corrigendum to “Peptidyl human heart chymase inhibitors. Part 2: Discovery of highly selective difluoromethylene ketone derivatives with Glu at P3 site” [Bioorg. Med. Chem. Lett. 8 (1998) 919]
Eda, Masahiro, Ashimori, Atsuyuki, Akahoshi, Fumihiko, Yoshimura, Takuya, Inoue, Yoshihisa, Fukaya, Chikara, Nakajima, Masahide, Fukuyama, Hajime, Imada, Teruaki, Nakamura, Norifumi
Published in Bioorganic & medicinal chemistry letters (01.07.1998)
Published in Bioorganic & medicinal chemistry letters (01.07.1998)
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