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Chuang, Chihyuan, Collibee, Scott, Ashcraft, Luke, Wang, Wenyue, Vander Wal, Mark, Wang, Xiaolin, Hwee, Darren T, Wu, Yangsong, Wang, Jingying, Chin, Eva R, Cremin, Peadar, Zamora, Jeanelle, Hartman, James, Schaletzky, Julia, Wehri, Eddie, Robertson, Laura A, Malik, Fady I, Morgan, Bradley P
Published in Journal of medicinal chemistry (14.10.2021)
Published in Journal of medicinal chemistry (14.10.2021)
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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295
Qian, Xiangping, McDonald, Andrew, Zhou, Han-Jie, Adams, Nicholas D, Parrish, Cynthia A, Duffy, Kevin J, Fitch, Duke M, Tedesco, Rosanna, Ashcraft, Luke W, Yao, Bing, Jiang, Hong, Huang, Jennifer K, Marin, Melchor V, Aroyan, Carrie E, Wang, Jianchao, Ahmed, Seyed, Burgess, Joelle L, Chaudhari, Amita M, Donatelli, Carla A, Darcy, Michael G, Ridgers, Lance H, Newlander, Ken A, Schmidt, Stanley J, Chai, Deping, Colón, Mariela, Zimmerman, Michael N, Lad, Latesh, Sakowicz, Roman, Schauer, Stephen, Belmont, Lisa, Baliga, Ramesh, Pierce, Daniel W, Finer, Jeffrey T, Wang, Zhengping, Morgan, Bradley P, Morgans, David J, Auger, Kurt R, Sung, Chiu-Mei, Carson, Jeff D, Luo, Lusong, Hugger, Erin D, Copeland, Robert A, Sutton, David, Elliott, John D, Jackson, Jeffrey R, Wood, Kenneth W, Dhanak, Dashyant, Bergnes, Gustave, Knight, Steven D
Published in ACS medicinal chemistry letters (08.04.2010)
Published in ACS medicinal chemistry letters (08.04.2010)
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Pharmacokinetics, Mass Balance, Tissue Distribution, Metabolism, and Excretion of [ 14 C]Aficamten Following Single Oral Dose Administration to Rats
Grillo, Mark P, Sukhun, Rajaa, Bashir, Mohammad, Ashcraft, Luke, Morgan, Bradley P
Published in Xenobiotica (07.08.2024)
Published in Xenobiotica (07.08.2024)
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Journal Article
Cardiac Troponin Activator CK-963 Increases Cardiac Contractility in Rats
Collibee, Scott E., Romero, Antonio, Muci, Alexander R., Hwee, Darren T., Chuang, Chihyuan, Hartman, James J., Motani, Alykhan S., Ashcraft, Luke, DeRosier, Andre, Grillo, Mark, Lu, Qing, Malik, Fady I., Morgan, Bradley P.
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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Journal Article
Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility
Romero, Antonio, Ashcraft, Luke, Chandra, Aroop, DiMassa, Vincent, Cremin, Peadar, Collibee, Scott E., Chuang, Chihyuan, Hartman, James, Hwee, Darren T., St. Jean, David, Malinowski, Justin, DeBenedetto, Mikkel, Moebius, David, Payette, Joshua, Vargas, Richard, Yeoman, John, Motani, Alykhan, Reagan, Jeffrey, Malik, Fady I., Morgan, Bradley P.
Published in Journal of medicinal chemistry (23.05.2024)
Published in Journal of medicinal chemistry (23.05.2024)
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Journal Article
Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function
Collibee, Scott E, Bergnes, Gustave, Chuang, Chihyuan, Ashcraft, Luke, Gardina, Jeffrey, Garard, Marc, Jamison, Chris R, Lu, Kevin, Lu, Pu-Ping, Muci, Alexander, Romero, Antonio, Valkevich, Ellen, Wang, Wenyue, Warrington, Jeffrey, Yao, Bing, Durham, Nickie, Hartman, James, Marquez, Anna, Hinken, Aaron, Schaletzky, Julia, Xu, Donghong, Hwee, Darren T, Morgans, David, Malik, Fady I, Morgan, Bradley P
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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In Vitro and In Vivo Pharmacokinetic Preclinical Characterization of Aficamten, a Small Molecule Cardiac Myosin Inhibitor
Sukhun, Rajaa, Cremin, Peadar, Xu, Donghong, Zamora, Jeanelle, Cheung, Jennifer, Ashcraft, Luke, Grillo, Mark P, Morgan, Bradley P
Published in Xenobiotica (05.08.2024)
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Published in Xenobiotica (05.08.2024)
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CD38 조절제 및 이의 사용 방법
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Year of Publication 12.04.2024
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Year of Publication 12.04.2024
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CERTAIN AMINO-PYRIDAZINES COMPOSITIONS THEREOF AND METHODS OF THEIR USE
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Year of Publication 09.02.2018
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Year of Publication 06.11.2018
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DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS
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Year of Publication 23.10.2024
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DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS
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ASHCRAFT, Luke W, CHUANG, Chihyuan, GARCIA, Alfredo, HO, Justin, MORGAN, Bradley P
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DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS
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Year of Publication 26.08.2024
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Year of Publication 26.08.2024
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Dihydrobenzofuran and inden analogs as cardiac sarcomere inhibitors
ASHCRAFT, Luke W, VANDERWAL, Mark, CHUANG, Chihyuan, WANG, Wenyue, MORGAN, Bradley P
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Year of Publication 01.08.2024
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DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS
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Year of Publication 30.07.2024
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