Three steps toward dose optimization for oncology dose finding
Liao, Jason J.Z., Asatiani, Ekaterine, Liu, Qingyang, Hou, Kevin
Published in Contemporary clinical trials communications (01.08.2024)
Published in Contemporary clinical trials communications (01.08.2024)
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Journal Article
FIGHT-302: first-line pemigatinib vs gemcitabine plus cisplatin for advanced cholangiocarcinoma with FGFR2 rearrangements
Bekaii-Saab, Tanios S, Valle, Juan W, Van Cutsem, Eric, Rimassa, Lorenza, Furuse, Junji, Ioka, Tatsuya, Melisi, Davide, Macarulla, Teresa, Bridgewater, John, Wasan, Harpreet, Borad, Mitesh J, Abou-Alfa, Ghassan K, Jiang, Ping, Lihou, Christine F, Zhen, Huiling, Asatiani, Ekaterine, Féliz, Luis, Vogel, Arndt
Published in Future oncology (London, England) (01.10.2020)
Published in Future oncology (London, England) (01.10.2020)
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Journal Article
A hybrid design for dose‐finding oncology clinical trials
Liao, Jason J. Z., Zhou, Feng, Zhou, Heng, Petruzzelli, Lilli, Hou, Kevin, Asatiani, Ekaterine
Published in International journal of cancer (01.11.2022)
Published in International journal of cancer (01.11.2022)
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Journal Article
Abstract C071: Pharmacokinetics and pharmacodynamics of pemigatinib, a potent and selective inhibitor of FGFR 1, 2, and 3, in patients with advanced malignancies
Ji, Tao, Lihou, Christine, Asatiani, Ekaterine, Féliz, Luis, Overholt, Heather, Landman, Robert, Chen, Xuejun, Yeleswaram, Swamy
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Abstract A077: FIGHT-207: Phase 2 study of pemigatinib in patients with previously treated, locally advanced/metastatic or unresectable solid tumor malignancies harboring activating fibroblast growth factor receptor (FGFR) gene alterations
Féliz, Luis, Asatiani, Ekaterine, Lihou, Christine, Zhen, Huiling, Silverman, Ian, Ahnert, Jordi Rodon
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Abstract CT059: Phase 2, open-label, multicenter study of the efficacy and safety of INCB054828 for metastatic or surgically unresectable urothelial carcinoma harboring fibroblast growth factor (FGF)/FGF receptor (FGFR) alterations
Shore, Neal D., Asatiani, Ekaterine, Lihou, Christine F., Zhen, Huiling, Gupta, Sumati
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract CT057: Phase 2, open-label, multicenter study to evaluate the efficacy and safety of INCB054828 in patients with myeloid/lymphoid neoplasms with fibroblast growth factor receptor 1 ( FGFR1 ) rearrangement
Verstovsek, Srdan, Rambaldi, Alessandro, Asatiani, Ekaterine, Lihou, Christine F., Zhen, Huiling, Hochhaus, Andreas
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
A Phase 1/2 Study of the Oral Novel JAK1 Inhibitor INCB052793 As Monotherapy and in Combination with Standard Therapies in Patients with Advanced Hematologic Malignancies
Zeidan, Amer M., Cook, Rachel J., Bordoni, Rodolfo, Asatiani, Ekaterine, Zhou, Gongfu, Faivre, Théa, Byrne, Michael, Savona, Michael R.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Abstract CT063: Phase 2, open-label, multicenter study of the efficacy and safety of INCB054828 in patients (pts) with advanced, metastatic, or surgically unresectable cholangiocarcinoma (CCA) with inadequate response to prior therapy
Borad, Mitesh J., Davis, S. Lindsey, Lowery, Maeve A., Asatiani, Ekaterine, Lihou, Christine F., Zhen, Huiling, Abou-Alfa, Ghassan K.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
A Phase 1/2 Study of the Oral Janus Kinase 1 Inhibitors INCB052793 and Itacitinib Alone or in Combination With Standard Therapies for Advanced Hematologic Malignancies
Zeidan, Amer M., Cook, Rachel J., Bordoni, Rodolfo, Berenson, James R., Edenfield, William J., Mohan, Sanjay, Zhou, Gongfu, Asatiani, Ekaterine, Srinivas, Nithya, Savona, Michael R.
Published in Clinical lymphoma, myeloma and leukemia (01.07.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.07.2022)
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Journal Article
Interim Results from Fight-203, a Phase 2, Open-Label, Multicenter Study Evaluating the Efficacy and Safety of Pemigatinib (INCB054828) in Patients with Myeloid/Lymphoid Neoplasms with Rearrangement of Fibroblast Growth Factor Receptor 1 (FGFR1)
Verstovsek, Srdan, Vannucchi, Alessandro M., Rambaldi, Alessandro, Gotlib, Jason R., Mead, Adam J., Hochhaus, Andreas, Kiladjian, Jean-Jacques, Hernandez Boluda, Juan Carlos, Asatiani, Ekaterine, Lihou, Christine, Zhen, Huiling, Reiter, Andreas
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
First-in-Human Study of INCB062079, a Fibroblast Growth Factor Receptor 4 Inhibitor, in Patients with Advanced Solid Tumors
Harding, James J., Jungels, Christiane, Machiels, Jean-Pascal, Smith, David C., Walker, Chris, Ji, Tao, Jiang, Ping, Li, Xin, Asatiani, Ekaterine, Van Cutsem, Eric, Abou-Alfa, Ghassan K.
Published in Targeted oncology (01.03.2023)
Published in Targeted oncology (01.03.2023)
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Journal Article
Abstract CT111: Preliminary results from a phase 1/2 study of INCB054828, a highly selective fibroblast growth factor receptor (FGFR) inhibitor, in patients with advanced malignancies
Saleh, Mansoor, Gutierrez, Martin E., Subbiah, Vivek, Smith, David C., Asatiani, Ekaterine, Lihou, Christine F., Zhen, Huiling, Yeleswaram, Swamy, Ji, Tao, Nemunaitis, John
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract CT243: Clinical trial simulation to inform dose selection of zilurgisertib, an ALK2 inhibitor, in patients with anemia due to myelofibrosis (MF)
Yang, Yan-ou, Yang, Hong, Lamothe, Betty, Stubbs, Matthew, McBride, Amanda, Seguy, Francis, Rockich, Kevin, Getsy, Jay, Wang, Phillip, Liu, Xiang, Jackson, Jeff, Asatiani, Ekaterine, Chen, Xuejun
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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Journal Article
Abstract A48: Anti-tumor activity of the MEK inhibitor pimasertib in combination with the PI3K/mTOR inhibitor SAR245409 in low-grade serous ovarian cancer
Sidhu, Sukhvinder S., Campana, Frank, Egile, Coumaran, Hsu, Karl, Goodstal, Samantha, Asatiani, Ekaterine, Damstrup, Lars, Lager, Joanne, Ogden, Janet, Vincent, Loic
Published in Clinical cancer research (01.10.2013)
Published in Clinical cancer research (01.10.2013)
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Journal Article
Incidence of Mucositis in Patients Treated With Temsirolimus‐Based Regimens and Correlation to Treatment Response
Liu, Xiaochun, LoRusso, Patricia, Mita, Monica, Piha‐Paul, Sarina, Hong, David S., Fu, Siqing, McQuinn, Lacey, Asatiani, Ekaterine, Doyle, Lawrence A., Chen, Helen X., Hess, Kenneth R., Kurzrock, Razelle, Naing, Aung
Published in The oncologist (Dayton, Ohio) (01.04.2014)
Published in The oncologist (Dayton, Ohio) (01.04.2014)
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Journal Article
A phase I dose-escalation study of MSC1992371A, an oral inhibitor of aurora and other kinases, in advanced hematologic malignancies
Graux, Carlos, Sonet, Anne, Maertens, Johan, Duyster, Justus, Greiner, Jochen, Chalandon, Yves, Martinelli, Giovanni, Hess, Dagmar, Heim, Dominik, Giles, Francis J, Kelly, Kevin R, Gianella-Borradori, Athos, Longerey, Blandine, Asatiani, Ekaterine, Rejeb, Narmyn, Ottmann, Oliver G
Published in Leukemia research (01.09.2013)
Published in Leukemia research (01.09.2013)
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Journal Article
Abstract LB-147: Combination of the MEK inhibitor, pimasertib (MSC1936369B), and the PI3K/mTOR inhibitor, SAR245409, in patients with advanced solid tumors: Results of a phase Ib dose-escalation trial
Infante, Jeffrey R., Gandi, Leena, Shapiro, Geoffrey, Rizvi, Naiyer, Burris, Howard A., Bendell, Johanna C., Baselga, José, Hsu, Karl, von Richter, Oliver, Locatelli, Giuseppe, Asatiani, Ekaterine, Heist, Rebecca S.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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