Rational engineering of Aerococcus viridans l-lactate oxidase for the mediator modification to achieve quasi-direct electron transfer type lactate sensor
Hiraka, Kentaro, Kojima, Katsuhiro, Tsugawa, Wakako, Asano, Ryutaro, Ikebukuro, Kazunori, Sode, Koji
Published in Biosensors & bioelectronics (01.03.2020)
Published in Biosensors & bioelectronics (01.03.2020)
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Journal Article
Rational design of direct electron transfer type l-lactate dehydrogenase for the development of multiplexed biosensor
Hiraka, Kentaro, Tsugawa, Wakako, Asano, Ryutaro, Yokus, Murat A., Ikebukuro, Kazunori, Daniele, Michael A., Sode, Koji
Published in Biosensors & bioelectronics (15.03.2021)
Published in Biosensors & bioelectronics (15.03.2021)
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Journal Article
Mechanism of action of a T cell-dependent bispecific antibody as a breakthrough immunotherapy against refractory colorectal cancer with an oncogenic mutation
Kamakura, Daisuke, Asano, Ryutaro, Kawai, Hiroki, Yasunaga, Masahiro
Published in Cancer Immunology, Immunotherapy (01.01.2021)
Published in Cancer Immunology, Immunotherapy (01.01.2021)
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Journal Article
Rapid, convenient, and highly sensitive detection of human hemoglobin in serum using a high-affinity bivalent antibody–enzyme complex
Miura, Daimei, Kimura, Hayato, Tsugawa, Wakako, Ikebukuro, Kazunori, Sode, Koji, Asano, Ryutaro
Published in Talanta (Oxford) (01.11.2021)
Published in Talanta (Oxford) (01.11.2021)
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Journal Article
Development of a Versatile Method to Construct Direct Electron Transfer-Type Enzyme Complexes Employing SpyCatcher/SpyTag System
Yanase, Takumi, Okuda-Shimazaki, Junko, Asano, Ryutaro, Ikebukuro, Kazunori, Sode, Koji, Tsugawa, Wakako
Published in International journal of molecular sciences (17.01.2023)
Published in International journal of molecular sciences (17.01.2023)
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Journal Article
Engineering the hinge region of human IgG1 Fc-fused bispecific antibodies to improve fragmentation resistance
Suzuki, Saori, Annaka, Hiroaki, Konno, Shota, Kumagai, Izumi, Asano, Ryutaro
Published in Scientific reports (22.11.2018)
Published in Scientific reports (22.11.2018)
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Journal Article
Exploration and Application of DNA-Binding Proteins to Make a Versatile DNA–Protein Covalent-Linking Patch (D-Pclip): The Case of a Biosensing Element
Komiya, Erika, Takamatsu, Shouhei, Miura, Daimei, Tsukakoshi, Kaori, Tsugawa, Wakako, Sode, Koji, Ikebukuro, Kazunori, Asano, Ryutaro
Published in Journal of the American Chemical Society (14.02.2024)
Published in Journal of the American Chemical Society (14.02.2024)
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Development of a POCT type insulin sensor employing anti-insulin single chain variable fragment based on faradaic electrochemical impedance spectroscopy under single frequency measurement
Khanwalker, Mukund, Fujita, Rinko, Lee, Jinhee, Wilson, Ellie, Ito, Kohei, Asano, Ryutaro, Ikebukuro, Kazunori, LaBelle, Jeffrey, Sode, Koji
Published in Biosensors & bioelectronics (15.03.2022)
Published in Biosensors & bioelectronics (15.03.2022)
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Journal Article
Construction of IgG–Fab2 bispecific antibody via intein-mediated protein trans-splicing reaction
Yamada, Risa, Nakahara, Ishin, Kumagai, Izumi, Asano, Ryutaro, Nakanishi, Takeshi, Makabe, Koki
Published in Scientific reports (25.09.2023)
Published in Scientific reports (25.09.2023)
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Journal Article
Strategic design and improvement of the internal electron transfer of heme b domain-fused glucose dehydrogenase for use in direct electron transfer-type glucose sensors
Ito, Kohei, Okuda-Shimazaki, Junko, Kojima, Katsuhiro, Mori, Kazushige, Tsugawa, Wakako, Asano, Ryutaro, Ikebukuro, Kazunori, Sode, Koji
Published in Biosensors & bioelectronics (15.03.2021)
Published in Biosensors & bioelectronics (15.03.2021)
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Journal Article
Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope
Makabe, Koki, Yokoyama, Takeshi, Uehara, Shiro, Uchikubo-Kamo, Tomomi, Shirouzu, Mikako, Kimura, Kouki, Tsumoto, Kouhei, Asano, Ryutaro, Tanaka, Yoshikazu, Kumagai, Izumi
Published in Scientific reports (11.03.2021)
Published in Scientific reports (11.03.2021)
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Journal Article
Structure of lactate oxidase from Enterococcus hirae revealed new aspects of active site loop function: Product‐inhibition mechanism and oxygen gatekeeper
Hiraka, Kentaro, Yoshida, Hiromi, Tsugawa, Wakako, Asano, Ryutaro, La Belle, Jeffrey T., Ikebukuro, Kazunori, Sode, Koji
Published in Protein science (01.10.2022)
Published in Protein science (01.10.2022)
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Journal Article
Construction of a circularly connected VHH bispecific antibody (cyclobody) for the desirable positioning of antigen-binding sites
Hemmi, Saki, Asano, Ryutaro, Kimura, Kouki, Umetsu, Mitsuo, Nakanishi, Takeshi, Kumagai, Izumi, Makabe, Koki
Published in Biochemical and biophysical research communications (26.02.2020)
Published in Biochemical and biophysical research communications (26.02.2020)
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Journal Article
Rapid and Convenient Single-Chain Variable Fragment-Employed Electrochemical C-Reactive Protein Detection System
Miura, Daimei, Motohashi, Saki, Goto, Ayaka, Kimura, Hayato, Tsugawa, Wakako, Sode, Koji, Ikebukuro, Kazunori, Asano, Ryutaro
Published in International journal of molecular sciences (01.03.2024)
Published in International journal of molecular sciences (01.03.2024)
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Journal Article