Contribution of synovial macrophages to rat advanced osteoarthritis pain resistant to cyclooxygenase inhibitors
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Published in Pain (Amsterdam) (01.04.2019)
Published in Pain (Amsterdam) (01.04.2019)
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Effect of spinal monoaminergic neuronal system dysfunction on pain threshold in rats, and the analgesic effect of serotonin and norepinephrine reuptake inhibitors
Tamano, Ryuta, Ishida, Mitsuhiro, Asaki, Toshiyuki, Hasegawa, Minoru, Shinohara, Shunji
Published in Neuroscience letters (26.02.2016)
Published in Neuroscience letters (26.02.2016)
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Transnasal transplantation of human induced pluripotent stem cell‐derived microglia to the brain of immunocompetent mice
Parajuli, Bijay, Saito, Hiroki, Shinozaki, Youichi, Shigetomi, Eiji, Miwa, Hiroto, Yoneda, Sosuke, Tanimura, Miki, Omachi, Shigeki, Asaki, Toshiyuki, Takahashi, Koji, Fujita, Masahide, Nakashima, Kinichi, Koizumi, Schuichi
Published in Glia (01.10.2021)
Published in Glia (01.10.2021)
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Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B
Hayano, Yasufumi, Takasu, Keiko, Koyama, Yoshihisa, Yamada, Moe, Ogawa, Koichi, Minami, Kazuhisa, Asaki, Toshiyuki, Kitada, Kazuhiro, Kuwabara, Satoshi, Yamashita, Toshihide
Published in The Journal of experimental medicine (12.12.2016)
Published in The Journal of experimental medicine (12.12.2016)
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Ibudilast produces anti-allodynic effects at the persistent phase of peripheral or central neuropathic pain in rats: Different inhibitory mechanism on spinal microglia from minocycline and propentofylline
Fujita, Masahide, Tamano, Ryuta, Yoneda, Sosuke, Omachi, Shigeki, Yogo, Erika, Rokushima, Masatomo, Shinohara, Shunji, Sakaguchi, Gaku, Hasegawa, Minoru, Asaki, Toshiyuki
Published in European journal of pharmacology (15.08.2018)
Published in European journal of pharmacology (15.08.2018)
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Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain
Tsuno, Naoki, Yukimasa, Akira, Yoshida, Osamu, Suzuki, Shinji, Nakai, Hiromi, Ogawa, Tomoyuki, Fujiu, Motohiro, Takaya, Kenji, Nozu, Azusa, Yamaguchi, Hiroki, Matsuda, Hidetoshi, Funaki, Satoko, Yamanada, Natsue, Tanimura, Miki, Nagamatsu, Daiki, Asaki, Toshiyuki, Horita, Narumi, Yamamoto, Miyuki, Hinata, Mikie, Soga, Masahiko, Imai, Masayuki, Morioka, Yasuhide, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Iso, Yasuyoshi
Published in Bioorganic & medicinal chemistry (01.04.2017)
Published in Bioorganic & medicinal chemistry (01.04.2017)
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Requirement of fibroblast growth factor 10 in development of white adipose tissue
Sakaue, Hiroshi, Konishi, Morichika, Ogawa, Wataru, Asaki, Toshiyuki, Mori, Toshiyuki, Yamasaki, Masahiro, Takata, Masafumi, Ueno, Hikaru, Kato, Shigeaki, Kasuga, Masato, Itoh, Nobuyuki
Published in Genes & development (15.04.2002)
Published in Genes & development (15.04.2002)
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Role of Fgf10 in cell proliferation in white adipose tissue
Konishi, Morichika, Asaki, Toshiyuki, Koike, Naomi, Miwa, Hiroyuki, Miyake, Ayumi, Itoh, Nobuyuki
Published in Molecular and cellular endocrinology (25.04.2006)
Published in Molecular and cellular endocrinology (25.04.2006)
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Identification of a novel fibroblast growth factor, FGF-22, preferentially expressed in the inner root sheath of the hair follicle
Nakatake, Yuhki, Hoshikawa, Masamitsu, Asaki, Toshiyuki, Kassai, Yoshiaki, Itoh, Nobuyuki
Published in Biochimica et biophysica acta (16.02.2001)
Published in Biochimica et biophysica acta (16.02.2001)
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Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo
Asaki, Toshiyuki, Konishi, Morichika, Miyake, Ayumi, Kato, Shigeaki, Tomizawa, Minoru, Itoh, Nobuyuki
Published in Molecular and cellular endocrinology (15.04.2004)
Published in Molecular and cellular endocrinology (15.04.2004)
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Duloxetine ameliorates the impairment of diffuse noxious inhibitory control in rat models of peripheral neuropathic pain and knee osteoarthritis pain
Yoneda, Sosuke, Kasai, Erika, Matsuo, Midori, Tamano, Ryuta, Sakurai, Yusuke, Asaki, Toshiyuki, Fujita, Masahide
Published in Neuroscience letters (11.06.2020)
Published in Neuroscience letters (11.06.2020)
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Selective blockade of transient receptor potential vanilloid 4 reduces cyclophosphamide-induced bladder pain in mice
Kawasaki, Shiori, Soga, Masahiko, Sakurai, Yusuke, Nanchi, Isamu, Yamamoto, Miyuki, Imai, Sunao, Takahashi, Tatsuya, Tsuno, Naoki, Asaki, Toshiyuki, Morioka, Yasuhide, Fujita, Masahide
Published in European journal of pharmacology (15.05.2021)
Published in European journal of pharmacology (15.05.2021)
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The antagonistic activity profile of naloxone in μ-opioid receptor agonist-induced psychological dependence
Nakamura, Atsushi, Yasufuku, Kana, Shimada, Shinji, Aritomi, Hiroyuki, Furue, Youko, Chiba, Hiroki, Muramoto, Mami, Takase, Kenji, Koike, Katsumi, Matsumoto, Tomoko, Shimada, Tomoka, Watari, Ryosuke, Matsuzaki, Takanobu, Asaki, Toshiyuki, Kanemasa, Toshiyuki, Fujita, Masahide
Published in Neuroscience letters (14.09.2020)
Published in Neuroscience letters (14.09.2020)
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The contribution of macrophage/monocyte to cyclooxygenase-independent pain in advanced osteoarthritis model in rats
Sakurai, Yusuke, Fujita, Masahide, Sanaki, Takao, Yoshioka, Takeshi, Higashino, Kenichi, Mochizuki, Kiyotaka, Takahashi, Tatsuya, Asaki, Toshiyuki, Hasegawa, Minoru, Morioka, Yasuhide
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Analgesic effects of a novel monoclonal antibody against Nav1.7 sodium channel
Yoneda, Sosuke, Kasai, Erika, Takahashi, Tatsuya, Yoshikawa, Mai, Onoda, Junji, Izumi, Takaya, Yamane, Shoji, Maekawa, Kazuhiko, Asaki, Toshiyuki, Hasegawa, Minoru
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Sensitization of TRPV1 by protein kinase C in rats with mono-iodoacetate-induced joint pain
Koda, Ken, Hyakkoku, Kana, Ogawa, Koichi, Takasu, Keiko, Imai, Sunao, Sakurai, Yusuke, Fujita, Masahide, Ono, Hiroko, Yamamoto, Miyuki, Fukuda, Isao, Yamane, Shoji, Morita, Atsushi, Asaki, Toshiyuki, Kanemasa, Toshiyuki, Sakaguchi, Gaku, Morioka, Yasuhide, PhD
Published in Osteoarthritis and cartilage (01.07.2016)
Published in Osteoarthritis and cartilage (01.07.2016)
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Structure–Activity Relationship Studies and Discovery of a Potent Transient Receptor Potential Vanilloid (TRPV1) Antagonist 4-[3-Chloro-5-[(1 S )-1,2-dihydroxyethyl]-2-pyridyl]- N -[5-(trifluoromethyl)-2-pyridyl]-3,6-dihydro-2 H -pyridine-1-carboxamide (V116517) as a Clinical Candidate for Pain Management
Tafesse, Laykea, Kanemasa, Toshiyuki, Kurose, Noriyuki, Yu, Jianming, Asaki, Toshiyuki, Wu, Gang, Iwamoto, Yuka, Yamaguchi, Yoshitaka, Ni, Chiyou, Engel, John, Tsuno, Naoki, Patel, Aniket, Zhou, Xiaoming, Shintani, Takuya, Brown, Kevin, Hasegawa, Tsuyoshi, Shet, Manjunath, Iso, Yasuyoshi, Kato, Akira, Kyle, Donald J.
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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Nav1.7 모노클로날 항체
ONODA JUNJI, ASAKI TOSHIYUKI, YONEDA SOSUKE, NAKAMURA ETSUO, KASAI ERIKA, MIYAUCHI TSUGUO, TAKAHASHI TATSUYA, YOSHIKAWA MAI
Year of Publication 10.02.2021
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Year of Publication 10.02.2021
Patent
Structure–Activity Relationship Studies and Discovery of a Potent Transient Receptor Potential Vanilloid (TRPV1) Antagonist 4‑[3-Chloro-5-[(1S)‑1,2-dihydroxyethyl]-2-pyridyl]‑N‑[5-(trifluoromethyl)-2-pyridyl]-3,6-dihydro‑2H‑pyridine-1-carboxamide (V116517) as a Clinical Candidate for Pain Management
Tafesse, Laykea, Kanemasa, Toshiyuki, Kurose, Noriyuki, Yu, Jianming, Asaki, Toshiyuki, Wu, Gang, Iwamoto, Yuka, Yamaguchi, Yoshitaka, Ni, Chiyou, Engel, John, Tsuno, Naoki, Patel, Aniket, Zhou, Xiaoming, Shintani, Takuya, Brown, Kevin, Hasegawa, Tsuyoshi, Shet, Manjunath, Iso, Yasuyoshi, Kato, Akira, Kyle, Donald J
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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