Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876
Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Published in ChemMedChem (19.10.2016)
Published in ChemMedChem (19.10.2016)
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Journal Article
Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies
Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)
Published in ChemMedChem (06.11.2018)
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BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients
Sugawara, Tatsuo, Lejeune, Pascale, Köhr, Silke, Neuhaus, Roland, Faus, Hortensia, Gelato, Kathy A, Busemann, Matthias, Cleve, Arwed, Lücking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik, Jung, Klaus, Stephan, Carsten, Haendler, Bernard
Published in Oncotarget (02.02.2016)
Published in Oncotarget (02.02.2016)
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Journal Article
Synthesis and Biological Activity of a Novel, Highly Potent Progesterone Receptor Antagonist
Fuhrmann, Ulrike, Hess-Stumpp, Holger, Cleve, Arwed, Neef, Günter, Schwede, Wolfgang, Hoffmann, Jens, Fritzemeier, Karl-Heinrich, Chwalisz, Kristof
Published in Journal of medicinal chemistry (28.12.2000)
Published in Journal of medicinal chemistry (28.12.2000)
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Journal Article
Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP Inhibitors In Vitro and In Vivo
Siemeister, Gerhard, Mengel, Anne, Fernández-Montalván, Amaury E, Bone, Wilhelm, Schröder, Jens, Zitzmann-Kolbe, Sabine, Briem, Hans, Prechtl, Stefan, Holton, Simon J, Mönning, Ursula, von Ahsen, Oliver, Johanssen, Sandra, Cleve, Arwed, Pütter, Vera, Hitchcock, Marion, von Nussbaum, Franz, Brands, Michael, Ziegelbauer, Karl, Mumberg, Dominik
Published in Clinical cancer research (15.02.2019)
Published in Clinical cancer research (15.02.2019)
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Front Cover: Discovery of Vilaprisan (BAY 1002670): A Highly Potent and Selective Progesterone Receptor Modulator Optimized for Gynecologic Therapies (ChemMedChem 21/2018)
Möller, Carsten, Bone, Wilhelm, Cleve, Arwed, Klar, Ulrich, Rotgeri, Andrea, Rottmann, Antje, Schultze‐Mosgau, Marcus‐Hillert, Wagenfeld, Andrea, Schwede, Wolfgang
Published in ChemMedChem (06.11.2018)
Published in ChemMedChem (06.11.2018)
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Journal Article
Abstract 4333: Identification and optimization of the first highly selective GLUT-1 inhibitors
Bauser, Marcus, Buchmann, Bernd, Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Mueller, Thomas, Kopitz, Charlotte Christine
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 287: BAY 1816032, a novel BUB1 kinase inhibitor with potent antitumor activity
Siemeister, Gerhard, Mengel, Anne, Bone, Wilhelm, Schröder, Jens, Zitzmann-Kolbe, Sabine, Briem, Hans, Fernández-Montalván, Amaury E., Holton, Simon, Mönning, Ursula, Ahsen, Oliver von, Johanssen, Sandra, Cleve, Arwed, Hitchcock, Marion, Meyer, Kirstin, Nussbaum, Franz von, Brands, Michael, Mumberg, Dominik, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Cover Picture: Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876 (ChemMedChem 20/2016)
Siebeneicher, Holger, Cleve, Arwed, Rehwinkel, Hartmut, Neuhaus, Roland, Heisler, Iring, Müller, Thomas, Bauser, Marcus, Buchmann, Bernd
Published in ChemMedChem (19.10.2016)
Published in ChemMedChem (19.10.2016)
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Journal Article
Abstract 1321: Castration-resistant prostate cancer: BAY 1024767 blocks function of mutated androgen receptor
Haendler, Bernard, Sugawara, Tatsuo, Lejeune, Pascale, Koehr, Silke, Faus, Hortensia, Busemann, Matthias, Cleve, Arwed, Luecking, Ulrich, von Nussbaum, Franz, Brands, Michael, Mumberg, Dominik
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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New Roles for LTA4 Hydrolase, LTB4 and BLT1 in Multiple Sclerosis and Experimental Allergic Encephalomyelitis (48.9)
Parkinson, John F, Guilford, William J, Mendoza, Lisa M, Rosser, Mary, Post, Joseph, Schaefer, Caralee, Halks-Miller, Meredith, Kirkland, Tom, Cleve, Arwed, Lassmann, Hans, Reder, Anthony T
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
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Beneficial effects of fluorine in the anti-progestin ZK 230211
Cleve, Arwed, Klar, Ulrich, Schwede, Wolfgang
Published in Journal of fluorine chemistry (01.02.2005)
Published in Journal of fluorine chemistry (01.02.2005)
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Aromatic sulfonamide derivatives
Werner, Stefan, Hardaker, Elizabeth, Herbert, Simon Anthony, Lishchynskyi, Anton, Koch, Markus, Dahllöf, Henrik, Osmers, Maren, Bräuer, Nico, Cleve, Arwed, Mesch, Stefanie
Year of Publication 13.12.2022
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Year of Publication 13.12.2022
Patent
AROMATIC SULFONAMIDE DERIVATIVES
HERBERT, Simon Anthony, KOCH, Markus, OSMERS, Maren, HARDAKER, Elizabeth, LISHCHYNSKYI, Anton, WERNER, Stefan, BRÄUER, Nico, DAHLLÖF, Henrik, CLEVE, Arwed, MESCH, Stefanie
Year of Publication 13.10.2022
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Year of Publication 13.10.2022
Patent
DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE
Light, David, Claret, Emmanuel, Brown, Greg, Liang, Amy, Ye, Bin, Davey, David, Guilford, William, Parkinson, John, Kochanny, Monica J, Kirkland, Thomas, Wei, Guo Ping, Cleve, Arwed, Arnaiz, Damian O, Khim, Seock-Kyu
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
Patent
AROMATIC SULFONAMIDE DERIVATIVES
HERBERT, Simon, DAHLLOEF, Henrik, KOCH, Markus, OSMERS, Maren, HARDAKER, Elizabeth, LISHCHYNSKYI, Anton, WERNER, Stefan, BRÄUER, Nico, CLEVE, Arwed, MESCH, Stefanie
Year of Publication 01.03.2021
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Year of Publication 01.03.2021
Patent
AROMATIC SULFONAMIDE DERIVATIVES
Werner, Stefan, Hardaker, Elizabeth, Lishchynskyi, Anton, Brauer, Niko, Koch, Markus, Herbert, Simon, Anthony, Dahllof, Henrik, Osmers, Maren, Cleve, Arwed, Mesch, Stefanie
Year of Publication 10.11.2021
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Year of Publication 10.11.2021
Patent