In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
Hartz, Richard A, Ahuja, Vijay T, Rafalski, Maria, Schmitz, William D, Brenner, Allison B, Denhart, Derek J, Ditta, Jonathan L, Deskus, Jeffrey A, Yue, Eddy W, Arvanitis, Argyrios G, Lelas, Snjezana, Li, Yu-Wen, Molski, Thaddeus F, Wong, Harvey, Grace, James E, Lentz, Kimberley A, Li, Jianqing, Lodge, Nicholas J, Zaczek, Robert, Combs, Andrew P, Olson, Richard E, Mattson, Ronald J, Bronson, Joanne J, Macor, John E
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Synthesis and evaluation of 2-anilino-3-phenylsulfonyl-6-methylpyridines as corticotropin-releasing factor1 receptor ligands
HARTZ, Richard A, ARVANITIS, Argyrios G, ARNOLD, Charles, RESCINITO, Joseph P, HUNG, Kimberly L, GE ZHANG, WONG, Harvey, LANGLEY, David R, GILLIGAN, Paul J, TRAINOR, George L
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Synthesis, Structure−Activity Relationships, and In Vivo Evaluation of N 3-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
Hartz, Richard A, Ahuja, Vijay T, Arvanitis, Argyrios G, Rafalski, Maria, Yue, Eddy W, Denhart, Derek J, Schmitz, William D, Ditta, Jonathan L, Deskus, Jeffrey A, Brenner, Allison B, Hobbs, Frank W, Payne, Joseph, Lelas, Snjezana, Li, Yu-Wen, Molski, Thaddeus F, Mattson, Gail K, Peng, Yong, Wong, Harvey, Grace, James E, Lentz, Kimberley A, Qian-Cutrone, Jingfang, Zhuo, Xiaoliang, Shu, Yue-Zhong, Lodge, Nicholas J, Zaczek, Robert, Combs, Andrew P, Olson, Richard E, Bronson, Joanne J, Mattson, Ronald J, Macor, John E
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Synthesis and structure–activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists
Dzierba, Carolyn D., Sielecki, Thais M., Arvanitis, Argyrios G., Galka, Amy, Johnson, Tricia L., Takvorian, Amy G., Rafalski, Maria, Kasireddy-Polam, Padmaja, Vig, Shikha, Dasgupta, Bireshwar, Zhang, Ge, Molski, Thaddeus F., Wong, Harvey, Zaczek, Robert C., Lodge, Nicholas J., Combs, Andrew P., Gilligan, Paul J., Trainor, George L., Bronson, Joanne J., Macor, John E.
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
Published in Bioorganic & medicinal chemistry letters (01.08.2012)
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3-4-7-23--4--1--1--3- HYDROXYL KETO AND GLUCURONIDE DERIVATIVES OF 3-4-7H-PYRROLO[23-D]PYRIMIDIN-4-YL-1H-PYRAZOL-1-YL-3-CYCLOPENTYLPROPANENITRILE
LI MEI, NEDZA FRANK M, SHILLING ADAM, SHEPARD STACEY, GALYA LAURINE G, RODGERS JAMES D, ARVANITIS ARGYRIOS G
Year of Publication 27.11.2018
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Year of Publication 27.11.2018
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3-4-7-23--4--1--1--3- HYDROXYL KETO AND GLUCURONIDE DERIVATIVES OF 3-4-7H-PYRROLO[23-D]PYRIMIDIN-4-YL-1H-PYRAZOL-1-YL-3-CYCLOPENTYLPROPANENITRILE
LI MEI, NEDZA FRANK M, SHILLING ADAM, SHEPARD STACEY, GALYA LAURINE G, RODGERS JAMES D, ARVANITIS ARGYRIOS G
Year of Publication 29.08.2017
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Year of Publication 29.08.2017
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Imidazo[4,5- b]pyridines as corticotropin releasing factor receptor ligands
Arvanitis, Argyrios G., Rescinito, Joseph T., Arnold, Charles R., Wilde, Richard G., Cain, Gary A., Sun, Jung Hui, Yan, Jia-Sheng, Teleha, Christopher A., Fitzgerald, Lawrence W., McElroy, John, Zaczek, Robert, Hartig, Paul R., Grossman, Scott, Arneric, Stephen P., Gilligan, Paul J., Olson, Richard E., Robertson, David W.
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
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CRF Ligands via suzuki and negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine
Arvanitis, Argyrios G., Arnold, Charles R., Fitzgerald, Lawrence W., Frietze, William E., Olson, Richard E., Gilligan, Paul J., Robertson, David W.
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HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINE AND PYRROLO[2,3-b]PYRIMIDINE AS JANUS KINASE INHIBITORS
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Year of Publication 05.11.2015
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Imidazo[4,5- c]pyridines as corticotropin releasing factor receptor ligands
Arvanitis, Argyrios G., Rescinito, Joseph T., Arnold, Charles R., Wilde, Richard G., Fitzgerald, Lawrence W., Zaczek, Robert, Hartig, Paul R., Grossman, Scott, Arneric, Stephen P., Gilligan, Paul J., Olson, Richard E., Robertson, David W.
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
Published in Bioorganic & medicinal chemistry letters (06.01.2003)
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N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-D]PYRIMIDINES AS JANUS KINASE INHIBITORS
STORACE LOUIS, SHEPARD STACEY, FOLMER BEVERLY, SHAO LIXIN, ZHU WENYU, WANG HAISHENG, RODGERS JAMES D, ARVANITIS ARGYRIOS G, GLENN JOSEPH P
Year of Publication 12.04.2012
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Year of Publication 12.04.2012
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Corrections to In Vitro Intrinsic Clearance-Based Optimization of N 3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
Hartz, Richard A., Ahuja, Vijay T., Rafalski, Maria, Schmitz, William D., Brenner, Allison B., Denhart, Derek J., Ditta, Jonathan L., Deskus, Jeffrey A., Yue, Eddy W., Arvanitis, Argyrios G., Lelas, Snjezana, Li, Yu-Wen, Molski, Thaddeus F., Wong, Harvey, Grace, James E., Lentz, Kimberley A., Li, Jianqing, Lodge, Nicholas J., Zaczek, Robert, Combs, Andrew P., Olson, Richard E., Mattson, Ronald J., Bronson, Joanne J., Macor, John E.
Published in Journal of medicinal chemistry (24.09.2009)
Published in Journal of medicinal chemistry (24.09.2009)
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Journal Article
In Vitro Intrinsic Clearance-Based Optimization of N3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
HARTZ, Richard A, AHUJA, Vijay T, LELAS, Snjezana, LI, Yu-Wen, MOLSKI, Thaddeus F, WONG, Harvey, GRACE, James E, LENTZ, Kimberley A, JIANQING LI, LODGE, Nicholas J, ZACZEK, Robert, COMBS, Andrew P, RAFALSKI, Maria, OLSON, Richard E, MATTSON, Ronald J, BRONSON, Joanne J, MACOR, John E, SCHMITZ, William D, BRENTER, Allison B, DENHART, Derek J, DITTA, Jonathan L, DESKUS, Jeffrey A, YUE, Eddy W, ARVANITIS, Argyrios G
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Journal Article
Synthesis, Structure—Activity Relationships, and In Vivo Evaluation of N3-Phenylpyrazinones as Novel Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
HARTZ, Richard A, AHUJA, Vijay T, HOBBS, Frank W, PAYNE, Joseph, LELAS, Snjezana, LI, Yu-Wen, MOLSKI, Thaddeus F, MATTSON, Gail K, YONG PENG, WONG, Harvey, GRACE, James E, LENTZ, Kimberley A, ARVANITIS, Argyrios G, QIAN-CUTRONE, Jingfang, XIAOLIANG ZHUO, SHU, Yue-Zhong, LODGER, Nicholas J, ZACZEK, Robert, COMBS, Andrew P, OLSON, Richard E, BRONSON, Joanne J, MATTSON, Ronald J, MACOR, John E, RAFALSKI, Maria, YUE, Eddy W, DENHART, Derek J, SCHMITZ, William D, DITTA, Jonathan L, DESKUS, Jeffrey A, BRENNER, Allison B
Published in Journal of medicinal chemistry (23.07.2009)
Published in Journal of medicinal chemistry (23.07.2009)
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Journal Article
Synthesis and evaluation of 2-anilino-3-phenylsulfonyl-6-methylpyridines as corticotropin-releasing factor sub(1) receptor ligands
Hartz, Richard A, Arvanitis, Argyrios G, Arnold, Charles, Rescinito, Joseph P, Hung, Kimberly L, Zhang, Ge, Wong, Harvey, Langley, David R, Gilligan, Paul J, Trainor, George L
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Synthesis and evaluation of 2-anilino-3-phenylsulfonyl-6-methylpyridines as corticotropin-releasing factor 1 receptor ligands
Hartz, Richard A., Arvanitis, Argyrios G., Arnold, Charles, Rescinito, Joseph P., Hung, Kimberly L., Zhang, Ge, Wong, Harvey, Langley, David R., Gilligan, Paul J., Trainor, George L.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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