Saxitoxin
Thottumkara, Arun P., Parsons, William H., Du Bois, J.
Published in Angewandte Chemie International Edition (02.06.2014)
Published in Angewandte Chemie International Edition (02.06.2014)
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Journal Article
Carbocyclization of unsaturated thioesters under palladium catalysis
Thottumkara, Arun P, Kurokawa, Toshiki, Du Bois, J
Published in Chemical science (Cambridge) (01.01.2013)
Published in Chemical science (Cambridge) (01.01.2013)
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Journal Article
SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons
Miyamoto, Takashi, Kim, Chaeyoung, Chow, Johann, Dugas, Jason C., DeGroot, Jack, Bagdasarian, Alex L., Thottumkara, Arun P., Larhammar, Martin, Calvert, Meredith EK, Fox, Brian M., Lewcock, Joseph W., Kane, Lesley A.
Published in The Journal of biological chemistry (01.02.2024)
Published in The Journal of biological chemistry (01.02.2024)
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Journal Article
Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors
Burnett, G. Leslie, Yang, Yu C., Aggen, James B., Pitzen, Jennifer, Gliedt, Micah K., Semko, Chris M., Marquez, Abby, Evans, James W., Wang, Gang, Won, Walter S., Tomlinson, Aidan C. A., Kiss, Gert, Tzitzilonis, Christos, Thottumkara, Arun P., Cregg, James, Mellem, Kevin T., Choi, Jong S., Lee, Julie C., Zhao, Yongyuan, Lee, Bianca J., Meyerowitz, Justin G., Knox, John E., Jiang, Jingjing, Wang, Zhican, Wildes, David, Wang, Zhengping, Singh, Mallika, Smith, Jacqueline A. M., Gill, Adrian L.
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Journal Article
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.10.2021)
Published in Nature chemical biology (01.10.2021)
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Journal Article
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
Kantarci, Husniye, Elvira, Pablo D., Thottumkara, Arun P., O’Connell, Emma M., Iyer, Manasi, Donovan, Lauren J., Dugan, Micaela Quinn, Ambiel, Nicholas, Granados, Alejandro, Zeng, Hong, Saw, Nay L., Brosius Lutz, Amanda, Sloan, Steven A., Gray, Erin E., Tran, Khanh V., Vichare, Aditi, Yeh, Ashley K., Münch, Alexandra E., Huber, Max, Agrawal, Aditi, Morri, Maurizio, Zhong, Haining, Shamloo, Mehrdad, Anderson, Thomas Anthony, Tawfik, Vivianne L., Du Bois, J., Zuchero, J. Bradley
Published in Cell (22.08.2024)
Published in Cell (22.08.2024)
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Journal Article
Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis
Craig, Robert A., Fox, Brian M., Hu, Cheng, Lexa, Katrina W., Osipov, Maksim, Thottumkara, Arun P., Larhammar, Martin, Miyamoto, Takashi, Rana, Anil, Kane, Lesley A., Yulyaningsih, Ernie, Solanoy, Hilda, Nguyen, Hoang, Chau, Roni, Earr, Timothy, Kajiwara, Yuji, Fleck, Daniel, Lucas, Anthony, Haddick, Patrick C. G., Takahashi, Ryan H., Tong, Vincent, Wang, Jing, Canet, Mark J., Poda, Suresh B., Scearce-Levie, Kimberly, Srivastava, Ankita, Sweeney, Zachary K., Xu, Musheng, Zhang, Rui, He, Jianrong, Lei, Yanan, Zhuo, Zheng, de Vicente, Javier
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Journal Article
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.08.2021)
Published in Nature chemical biology (01.08.2021)
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Journal Article
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.11.2021)
Published in Nature chemical biology (01.11.2021)
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Journal Article
DERIVATIVES OF AMPHOTERICIN B
ARUN P THOTTUMKARA, MARTIN D BURKE, ELENA S KOLTUN, KEVIN T MELLEM, ZACHARY K SWEENEY
Year of Publication 20.05.2021
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Year of Publication 20.05.2021
Patent
C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS
JAMES JOSEPH CREGG, CHRISTOPHER MICHAEL SEMKO, ARUN P THOTTUMKARA, MICAH JAMES EVANS GLIEDT, GERT KISS, ADRIAN LIAM GILL, G LESLIE BURNETT, WALTER WON, WANG GANG, KEVIN T MELLEM, JULIE CHU-LI LEE, JENNIFER PITZEN, JAMES BRADLEY AGGEN
Year of Publication 26.12.2023
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Year of Publication 26.12.2023
Patent
RAPAMYCIN ANALOGS AS MTOR INHIBITORS
ARUN P THOTTUMKARA, NIDHI TIBREWAL, MICAH JAMES EVANS GLIEDT, WANG GANG, CHRISTOPHER SEMKO, JULIE CHU-LI LEE, GERT KISS, JENNIFER PITZEN, JAMES BRADLEY AGGEN, ADRIAN LIAM GILL, G LESLIE BURNETT, WALTER WON
Year of Publication 26.07.2023
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Year of Publication 26.07.2023
Patent
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth (vol 17, pg 1065, 2021)
Lee, BJ, Boyer, JA, Burnett, GL, Thottumkara, AP, Tibrewal, N, Wilson, SL, Hsieh, T, Marquez, A, Lorenzana, EG, Evans, JW
Published in NATURE CHEMICAL BIOLOGY (01.11.2021)
Published in NATURE CHEMICAL BIOLOGY (01.11.2021)
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Publication
Schwann cell-secreted PGE 2 promotes sensory neuron excitability during development
Kantarci, Husniye, Elvira, Pablo D, Thottumkara, Arun P, O'Connell, Emma M, Iyer, Manasi, Donovan, Lauren J, Dugan, Micaela Quinn, Ambiel, Nicholas, Granados, Alejandro, Zeng, Hong, Saw, Nay L, Brosius Lutz, Amanda, Sloan, Steven A, Gray, Erin E, Tran, Khanh V, Vichare, Aditi, Yeh, Ashley K, Münch, Alexandra E, Huber, Max, Agrawal, Aditi, Morri, Maurizio, Zhong, Haining, Shamloo, Mehrdad, Anderson, Thomas Anthony, Tawfik, Vivianne L, Du Bois, J, Zuchero, J Bradley
Published in Cell (22.08.2024)
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Published in Cell (22.08.2024)
Journal Article