PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment
Guerrero-Zotano, Angel, Mayer, Ingrid A., Arteaga, Carlos L.
Published in Cancer and metastasis reviews (01.12.2016)
Published in Cancer and metastasis reviews (01.12.2016)
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Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer
MILLER, Todd W, BALKO, Justin M, ARTEAGA, Carlos L
Published in Journal of clinical oncology (20.11.2011)
Published in Journal of clinical oncology (20.11.2011)
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MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation
Lee, Kyung-min, Giltnane, Jennifer M., Balko, Justin M., Schwarz, Luis J., Guerrero-Zotano, Angel L., Hutchinson, Katherine E., Nixon, Mellissa J., Estrada, Mónica V., Sánchez, Violeta, Sanders, Melinda E., Lee, Taekyu, Gómez, Henry, Lluch, Ana, Pérez-Fidalgo, J. Alejandro, Wolf, Melissa Magdalene, Andrejeva, Gabriela, Rathmell, Jeffrey C., Fesik, Stephen W., Arteaga, Carlos L.
Published in Cell metabolism (03.10.2017)
Published in Cell metabolism (03.10.2017)
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Feedback upregulation of HER3 (ErbB3) expression and activity attenuates antitumor effect of PI3K inhibitors
Chakrabarty, Anindita, Sánchez, Violeta, Kuba, María G, Rinehart, Cammie, Arteaga, Carlos L
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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The Epidermal Growth Factor Receptor: From Mutant Oncogene in Nonhuman Cancers to Therapeutic Target in Human Neoplasia
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Conference Proceeding
Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer
Hortobagyi, Gabriel N, Stemmer, Salomon M, Burris, Howard A, Yap, Yoon-Sim, Sonke, Gabe S, Paluch-Shimon, Shani, Campone, Mario, Blackwell, Kimberly L, André, Fabrice, Winer, Eric P, Janni, Wolfgang, Verma, Sunil, Conte, Pierfranco, Arteaga, Carlos L, Cameron, David A, Petrakova, Katarina, Hart, Lowell L, Villanueva, Cristian, Chan, Arlene, Jakobsen, Erik, Nusch, Arnd, Burdaeva, Olga, Grischke, Eva-Maria, Alba, Emilio, Wist, Erik, Marschner, Norbert, Favret, Anne M, Yardley, Denise, Bachelot, Thomas, Tseng, Ling-Ming, Blau, Sibel, Xuan, Fengjuan, Souami, Farida, Miller, Michelle, Germa, Caroline, Hirawat, Samit, O’Shaughnessy, Joyce
Published in The New England journal of medicine (03.11.2016)
Published in The New England journal of medicine (03.11.2016)
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MEK Inhibition Leads to PI3K/AKT Activation by Relieving a Negative Feedback on ERBB Receptors
TURKE, Alexa B, SONG, Youngchul, COSTA, Carlotta, COOK, Rebecca, ARTEAGA, Carlos L, ASARA, John M, ENGELMAN, Jeffrey A
Published in Cancer research (Chicago, Ill.) (01.07.2012)
Published in Cancer research (Chicago, Ill.) (01.07.2012)
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TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association
Zonneville, Justin, Safina, Alfiya, Truskinovsky, Alexander M, Arteaga, Carlos L, Bakin, Andrei V
Published in BMC cancer (19.06.2018)
Published in BMC cancer (19.06.2018)
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Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors
Patel, Hitisha K, Tao, Nianjun, Lee, Kyung-Min, Huerta, Mariela, Arlt, Heike, Mullarkey, Tara, Troy, Steven, Arteaga, Carlos L, Bihani, Teeru
Published in Breast cancer research : BCR (18.12.2019)
Published in Breast cancer research : BCR (18.12.2019)
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Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial
Baselga, José, Prof, Im, Seock-Ah, Prof, Iwata, Hiroji, MD, Cortés, Javier, MD, De Laurentiis, Michele, MD, Jiang, Zefei, Prof, Arteaga, Carlos L, Prof, Jonat, Walter, Prof, Clemons, Mark, Prof, Ito, Yoshinori, MD, Awada, Ahmad, Prof, Chia, Stephen, MD, Jagiełło-Gruszfeld, Agnieszka, MD, Pistilli, Barbara, MD, Tseng, Ling-Ming, MD, Hurvitz, Sara, MD, Masuda, Norikazu, MD, Takahashi, Masato, MD, Vuylsteke, Peter, MD, Hachemi, Soulef, PhD, Dharan, Bharani, MS, Di Tomaso, Emmanuelle, PhD, Urban, Patrick, MD, Massacesi, Cristian, MD, Campone, Mario, Prof
Published in The lancet oncology (01.07.2017)
Published in The lancet oncology (01.07.2017)
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PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors
Lehmann, Brian D, Bauer, Joshua A, Schafer, Johanna M, Pendleton, Christopher S, Tang, Luojia, Johnson, Kimberly C, Chen, Xi, Balko, Justin M, Gómez, Henry, Arteaga, Carlos L, Mills, Gordon B, Sanders, Melinda E, Pietenpol, Jennifer A
Published in Breast cancer research : BCR (08.08.2014)
Published in Breast cancer research : BCR (08.08.2014)
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