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Huang, Xiaohua, Cheng, Cliff C., Fischmann, Thierry O., Duca, José S., Richards, Matthew, Tadikonda, Praveen K., Reddy, Panduranga Adulla, Zhao, Lianyun, Arshad Siddiqui, M., Parry, David, Davis, Nicole, Seghezzi, Wolfgang, Wiswell, Derek, Shipps, Gerald W.
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Faruk Mansoor, U., Vitharana, Dilrukshi, Reddy, Panduranga Adulla, Daubaras, Dayna L., McNicholas, Paul, Orth, Peter, Black, Todd, Arshad Siddiqui, M.
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
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Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors
Zhao, Lianyun, Zhang, Yingxin, Dai, Chaoyang, Guzi, Timothy, Wiswell, Derek, Seghezzi, Wolfgang, Parry, David, Fischmann, Thierry, Siddiqui, M. Arshad
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
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Discovery and SAR of hydantoin TACE inhibitors
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Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Potency switch between CHK1 and MK2: Discovery of imidazo[1,2-a]pyrazine- and imidazo[1,2-c]pyrimidine-based kinase inhibitors
Meng, Zhaoyang, Ciavarri, Jeffrey P., McRiner, Andrew, Zhao, Yinyan, Zhao, Lianyun, Reddy, Panduranga Adulla, Zhang, Xingmin, Fischmann, Thierry O., Whitehurst, Charles, Arshad Siddiqui, M.
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
Published in Bioorganic & medicinal chemistry letters (15.05.2013)
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Discovery of novel imidazo[1,2- a]pyrazin-8-amines as Brk/PTK6 inhibitors
Zeng, Hongbo, Belanger, David B., Curran, Patrick J., Shipps, Gerald W., Miao, Hua, Bracken, Jack B., Arshad Siddiqui, M., Malkowski, Michael, Wang, Yan
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
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Pyrazolo[1,5- a]pyrimidine-based inhibitors of HCV polymerase
Popovici-Muller, Janeta, Shipps, Gerald W., Rosner, Kristin E., Deng, Yongqi, Wang, Tong, Curran, Patrick J., Brown, Meredith A., Siddiqui, M. Arshad, Cooper, Alan B., Duca, José, Cable, Michael, Girijavallabhan, Viyyoor
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Method for Quantitative Protein−Ligand Affinity Measurements in Compound Mixtures
Annis, D. Allen, Shipps, Gerald W, Deng, Yongqi, Popovici-Müller, Janeta, Siddiqui, M. Arshad, Curran, Patrick J, Gowen, Matthew, Windsor, William T
Published in Analytical chemistry (Washington) (15.06.2007)
Published in Analytical chemistry (Washington) (15.06.2007)
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2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors
Dai, Chaoyang, Li, Dansu, Popovici-Muller, Janeta, Zhao, Lianyun, Girijavallabhan, Vinay M., Rosner, Kristin E., Lavey, Brian J., Rizvi, Razia, Shankar, Bandarpalle B., Wong, Michael K.C., Guo, Zhuyan, Orth, Peter, Strickland, Corey O., Sun, Jing, Niu, Xiaoda, Chen, Shiying, Kozlowski, Joseph A., Lundell, Daniel J., Piwinski, John J., Shih, Neng-Yang, Siddiqui, M. Arshad
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors
Meng, Zhaoyang, Kulkarni, Bheemashankar A., Kerekes, Angela D., Mandal, Amit K., Esposite, Sara J., Belanger, David B., Reddy, Panduranga Adulla, Basso, Andrea D., Tevar, Seema, Gray, Kimberly, Jones, Jennifer, Smith, Elizabeth B., Doll, Ronald J., Siddiqui, M. Arshad
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors
Belanger, David B., Williams, Michael J., Curran, Patrick J., Mandal, Amit K., Meng, Zhaoyang, Rainka, Matthew P., Yu, Tao, Shih, Neng-Yang, Siddiqui, M. Arshad, Liu, Ming, Tevar, Seema, Lee, Suining, Liang, Lianzhu, Gray, Kimberly, Yaremko, Bohdan, Jones, Jennifer, Smith, Elizabeth B., Prelusky, Dan B., Basso, Andrea D.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Discovery of 4H-pyrazolo[1,5-a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase
YONGQI DENG, SHIPPS, Gerald W, TONG WANG, POPOVICI-MULLER, Janeta, ROSNER, Kristin E, ARSHAD SIDDIQUI, M, DUCA, Jose, COOPER, Alan B, CABLE, Michael
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
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The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors
Rosner, Kristin E., Guo, Zhuyan, Orth, Peter, Shipps, Gerald W., Belanger, David B., Chan, Tin Yau, Curran, Patrick J., Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M., Hong, Liwu, Lavey, Brian J., Lee, Joe F., Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C., Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng -Yang, Arshad Siddiqui, M., Strickland, Corey O.
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases
Girijavallabhan, Vinay M., Chen, Lei, Dai, Chaoyang, Feltz, Robert J., Firmansjah, Luke, Li, Dansu, Kim, Seong Heon, Kozlowski, Joseph A., Lavey, Brian J., Kosinski, Aneta, Piwinski, John J., Popovici-Muller, Janeta, Rizvi, Razia, Rosner, Kristin E., Shankar, Banderpalle B., Shih, Neng-Yang, Siddiqui, M. Arshad, Tong, Ling, Wong, Michael K.C., Yang, De-yi, Yang, Liping, Yu, Wensheng, Zhou, Guowei, Guo, Zhuyan, Orth, Peter, Madison, Vincent, Bian, Hong, Lundell, Daniel, Niu, Xiaoda, Shah, Himanshu, Sun, Jing, Umland, Shelby
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
Published in Bioorganic & medicinal chemistry letters (15.12.2010)
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Structure and activity relationships of tartrate-based TACE inhibitors
Li, Dansu, Popovici-Muller, Janeta, Belanger, David B., Caldwell, John, Dai, Chaoyang, David, Maria, Girijavallabhan, Vinay M., Lavey, Brian J., Lee, Joe F., Liu, Zhidan, Mazzola, Rob, Rizvi, Razia, Rosner, Kristin E., Shankar, Bandarpalle, Spitler, Jim, Ting, Pauline C., Vaccaro, Henry, Yu, Wensheng, Zhou, Guowei, Zhu, Zhaoning, Niu, Xiaoda, Sun, Jing, Guo, Zhuyan, Orth, Peter, Chen, Shiying, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng-Yang, Shipps, Gerald W., Siddiqui, M. Arshad, Strickland, Corey O.
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
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Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core
Yu, Tao, Tagat, Jayaram R, Kerekes, Angela D, Doll, Ronald J, Zhang, Yonglian, Xiao, Yushi, Esposite, Sara, Belanger, David B, Curran, Patrick J, Mandal, Amit K, Siddiqui, M. Arshad, Shih, Neng-Yang, Basso, Andrea D, Liu, Ming, Gray, Kimberly, Tevar, Seema, Jones, Jennifer, Lee, Suining, Liang, Lianzhu, Ponery, Samad, Smith, Elizabeth B, Hruza, Alan, Voigt, Johannes, Ramanathan, Lata, Prosise, Winifred, Hu, Mengwei
Published in ACS medicinal chemistry letters (12.08.2010)
Published in ACS medicinal chemistry letters (12.08.2010)
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Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors
Tong, Ling, Kim, Seong Heon, Rosner, Kristin, Yu, Wensheng, Shankar, Bandarpalle B., Chen, Lei, Li, Dansu, Dai, Chaoyang, Girijavallabhan, Vinay, Popovici-Muller, Janeta, Yang, Liping, Zhou, Guowei, Kosinski, Aneta, Siddiqui, M. Arshad, Shih, Neng-Yang, Guo, Zhuyan, Orth, Peter, Chen, Shiying, Lundell, Daniel, Niu, Xiaoda, Umland, Shelby, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (15.07.2017)
Published in Bioorganic & medicinal chemistry letters (15.07.2017)
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Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors
Mansoor, Umar Faruk, Angeles, Angie R., Dai, Chaoyang, Yang, Liping, Vitharana, Dilrukshi, Basso, Andrea D., Gray, Kimberly, Tang, Huadong, Liu, Ming, Liang, Lianzhu, Allbritton, Omaira, Siddiqui, M. Arshad
Published in Bioorganic & medicinal chemistry (15.05.2015)
Published in Bioorganic & medicinal chemistry (15.05.2015)
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Discovery of imidazo[1,2- a]pyrazine-based Aurora kinase inhibitors
Belanger, David B., Curran, Patrick J., Hruza, Alan, Voigt, Johannes, Meng, Zhaoyang, Mandal, Amit K., Siddiqui, M. Arshad, Basso, Andrea D., Gray, Kimberly
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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