Search Results - "ARRUDA, JEANNIE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)

5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)

by Hutchinson, John H, Li, Yiwei, Arruda, Jeannie M, Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher D, Lee, Catherine, Lorrain, Dan, Prodanovich, Pat, Rong, Haojing, Santini, Angelina, Stock, Nicholas, Prasit, Peppi, Evans, Jilly F
Published in Journal of medicinal chemistry (08.10.2009)

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Journal Article

Pharmacological Characterization of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation

Pharmacological Characterization of 3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation

by Lorrain, Daniel S, Bain, Gretchen, Correa, Lucia D, Chapman, Charles, Broadhead, Alex R, Santini, Angelina M, Prodanovich, Pat, Darlington, Janice V, Hutchinson, John H, King, Christopher, Lee, Catherine, Baccei, Christopher, Li, Yiwei, Arruda, Jeannie M, Evans, Jilly F
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)

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Journal Article

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: high-affinity ligands to the α2δ subunit of voltage gated calcium channels

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: high-affinity ligands to the α2δ subunit of voltage gated calcium channels

by STEARNS, Brian A, ANKER, Naomi, SABLAD, Marciano, SANTINI, Angelina, SCHAFFHAUSER, Herve, URBAN, Mark O, MUNOZ, Benito, ARRUDA, Jeannie M, CAMPBELL, Brian T, CHIXU CHEN, CRAMER, Merryl, TAO HU, XIAOHUI JIANG, PARK, Kenneth, KUN KUN REN
Published in Bioorganic & medicinal chemistry letters (08.03.2004)

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Journal Article

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]-pyridazine derivatives as high-affinity ligands of the α2δ subunit of voltage-gated calcium channels

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]-pyridazine derivatives as high-affinity ligands of the α2δ subunit of voltage-gated calcium channels

by TAO HU, STEARNS, Brian A, VENKATRAMAN, Shankar, MUNOZ, Benito, CAMPBELL, Brian T, ARRUDA, Jeannie M, CHIXU CHEN, AIYAR, Jayashree, BEZVERKOV, Robert E, SANTINI, Angelina, SCHAFFHAUSER, Hervé, WENSHENG LIU
Published in Bioorganic & medicinal chemistry letters (03.05.2004)

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Journal Article

Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels : Generation of a focused library using a solution-phase Sn2Ar coupling methodology

Expedited SAR study of high-affinity ligands to the α2δ subunit of voltage-gated calcium channels : Generation of a focused library using a solution-phase Sn2Ar coupling methodology

by CHIXU CHEN, STEARNS, Brian, TAO HU, ANKER, Naomi, SANTINI, Angelina, ARRUDA, Jeannie M, CAMPBELL, Brian T, DATTA, Purabi, AIYAR, Jayashree, MUNOZ, Benitio
Published in Bioorganic & medicinal chemistry letters (01.02.2006)

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Journal Article

Protonation of β-Cyanoenamines: NMR Spectroscopic and Calculational Studies of Ketenimine Amidinium Ion Formation

Protonation of β-Cyanoenamines: NMR Spectroscopic and Calculational Studies of Ketenimine Amidinium Ion Formation

by Dwyer, Tammy J, Jasien, Paul G, Kirkowski, Scott M, Buxton, Charles M, Arruda, Jeannie M, Mitchell, Gregory W
Published in Journal of the American Chemical Society (16.12.1998)

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Journal Article

POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

by WANG BOWEI, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, ROPPE JEFFREY ROGER, ARRUDA JEANNIE M, PARR TIMOTHY
Year of Publication 15.06.2016

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Patent

Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors

Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors

by Siu, Tony, Liang, Jun, Arruda, Jeannie, Li, Yiwei, Jones, Raymond E., Defeo-Jones, Deborah, Barnett, Stanley F., Robinson, Ronald G.
Published in Bioorganic & medicinal chemistry (15.07.2008)

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Journal Article

Pharmacological Characterization of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation

Pharmacological Characterization of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103), a Novel Selective 5-Lipoxygenase-Activating Protein Inhibitor That Reduces Acute and Chronic Inflammation

by Lorrain, Daniel S., Bain, Gretchen, Correa, Lucia D., Chapman, Charles, Broadhead, Alex R., Santini, Angelina M., Prodanovich, Pat, Darlington, Janice V., Hutchinson, John H., King, Christopher, Lee, Catherine, Baccei, Christopher, Li, Yiwei, Arruda, Jeannie M., Evans, Jilly F.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2009)

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Journal Article

5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)

5-Lipoxygenase-Activating Protein Inhibitors: Development of 3-[3- tert -Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1 H -indol-2-yl]-2,2-dimethyl-propionic Acid (AM103)

by Hutchinson, John H., Li, Yiwei, Arruda, Jeannie M., Baccei, Christopher, Bain, Gretchen, Chapman, Charles, Correa, Lucia, Darlington, Janice, King, Christopher D., Lee, Catherine, Lorrain, Dan, Prodanovich, Pat, Rong, Haojing, Santini, Angelina, Stock, Nicholas, Prasit, Peppi, Evans, Jilly F.
Published in Journal of medicinal chemistry (08.10.2009)

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Journal Article

POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

by WANG BOWEI, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, ROPPE JEFFREY ROGER, ARRUDA JEANNIE M, PARR TIMOTHY
Year of Publication 19.03.2012

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Patent

Expedited SAR study of high-affinity ligands to the α 2δ subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

Expedited SAR study of high-affinity ligands to the α 2δ subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

by Chen, Chixu, Stearns, Brian, Hu, Tao, Anker, Naomi, Santini, Angelina, Arruda, Jeannie M., Campbell, Brian T., Datta, Purabi, Aiyar, Jayashree, Munoz, Benitio
Published in Bioorganic & medicinal chemistry letters (01.02.2006)

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Journal Article

ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS

by WANG BOWEI, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, ROPPE JEFFREY ROGER, ARRUDA JEANNIE M, PARR TIMOTHY
Year of Publication 21.07.2011

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Patent

POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

POLYCYCLIC COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

by CLARK RYAN, ZALATAN DAVID NATHAN, SEIDERS THOMAS JON, STEARNS BRIAN ANDREW, VOLKOTS DEBORAH, ZHAO LUCY, ARRUDA JEANNIE M
Year of Publication 04.09.2012

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Patent

ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

by WANG BOWEI, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, STEARNS BRIAN ANDREW, ARRUDA JEANNIE M
Year of Publication 07.03.2011

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Patent

Expedited SAR study of high-affinity ligands to the alpha(2)delta subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

Expedited SAR study of high-affinity ligands to the alpha(2)delta subunit of voltage-gated calcium channels: Generation of a focused library using a solution-phase Sn2Ar coupling methodology

by Chen, Chixu, Stearns, Brian, Hu, Tao, Anker, Naomi, Santini, Angelina, Arruda, Jeannie M, Campbell, Brian T, Datta, Purabi, Aiyar, Jayashree, Munoz, Benitio
Published in Bioorganic & medicinal chemistry letters (01.02.2006)

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Journal Article

N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

by WANG BOWEI, STOCK NICHOLAS SIMON, TRUONG YEN PHAM, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, SCOTT JILL MELISSA, STEARNS BRIAN ANDREW, VOLKOTS DEBORAH, ROPPE JEFFREY ROGER, ARRUDA JEANNIE M
Year of Publication 30.11.2010

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Patent

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels

Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels

by Hu, Tao, Stearns, Brian A, Campbell, Brian T, Arruda, Jeannie M, Chen, Chixu, Aiyar, Jayashree, Bezverkov, Robert E, Santini, Angelina, Schaffhauser, Hervé, Liu, Wensheng, Venkatraman, Shankar, Munoz, Benito
Published in Bioorganic & medicinal chemistry letters (03.05.2004)

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Journal Article

Synthesis and biological evaluation of 6-aryl-6 H -pyrrolo[3,4- d ]pyridazine derivatives as high-affinity ligands of the α 2 δ subunit of voltage-gated calcium channels

Synthesis and biological evaluation of 6-aryl-6 H -pyrrolo[3,4- d ]pyridazine derivatives as high-affinity ligands of the α 2 δ subunit of voltage-gated calcium channels

by Hu, Tao, Stearns, Brian A, Campbell, Brian T, Arruda, Jeannie M, Chen, Chixu, Aiyar, Jayashree, Bezverkov, Robert E, Santini, Angelina, Schaffhauser, Hervé, Liu, Wensheng, Venkatraman, Shankar, Munoz, Benito
Published in Bioorganic & medicinal chemistry letters (01.05.2004)

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Journal Article

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS

by WANG BOWEI, PRASIT PETPIBOON PEPPI, STOCK NICHOLAS SIMON, TRUONG YEN PHAM, HUTCHINSON JOHN HOWARD, SEIDERS THOMAS JON, HADDACH MUSTAPHA, SCOTT JILL MELISSA, ROPPE JEFFREY ROGER, LI YIWEI, EVANS JILLIAN F, STEARNS BRIAN ANDREW, MORAN MARK, ZUNIC JASMINE ELEANOR, ARRUDA JEANNIE M
Year of Publication 07.04.2010

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