XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases
Owyang, Alexander M., Issafras, Hassan, Corbin, John, Ahluwalia, Kiran, Larsen, Paul, Pongo, Elizabeth, Handa, Masahisa, Horwitz, Arnold H., Roell, Marina K., Haak-Frendscho, Mary, Masat, Linda
Published in mAbs (01.01.2011)
Published in mAbs (01.01.2011)
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Antibody engineering to improve manufacturability
Wijesuriya, Sujeewa D., Pongo, Elizabeth, Tomic, Milan, Zhang, Fangjiu, Garcia-Rodriquez, Consuelo, Conrad, Fraser, Farr-Jones, Shauna, Marks, James D., Horwitz, Arnold H.
Published in Protein expression and purification (01.09.2018)
Published in Protein expression and purification (01.09.2018)
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An allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lep(ob) /Lep(ob) mouse
Bhaskar, Vinay, Goldfine, Ira D, Gerstner, Resi, Michelson, Kristen, Tran, Catarina, Nonet, Genevieve, Bohmann, David, Pongo, Elizabeth, Zhao, Jingsong, Horwitz, Arnold H, Takeuchi, Toshihiko, White, Mark, Corbin, John A
Published in Obesity (Silver Spring, Md.) (01.08.2016)
Published in Obesity (Silver Spring, Md.) (01.08.2016)
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Enhancement of antibody fragment secretion into the Escherichia coli periplasm by co-expression with the peptidyl prolyl isomerase, FkpA, in the cytoplasm
Levy, Raphael, Ahluwalia, Kiran, Bohmann, David J., Giang, Hoa M., Schwimmer, Lauren J., Issafras, Hassan, Reddy, Nithin B., Chan, Chung, Horwitz, Arnold H., Takeuchi, Toshihiko
Published in Journal of immunological methods (30.08.2013)
Published in Journal of immunological methods (30.08.2013)
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In Vitro and In Vivo Pharmacology and Pharmacokinetics of a Human Engineered™ Monoclonal Antibody to Epithelial Cell Adhesion Molecule
Ammons, W. Steve, Bauer, Robert J., Horwitz, Arnold H., Chen, Zhi J., Bautista, Eddie, Ruan, Harry H., Abramova, Marina, Scott, Kristen R., Dedrick, Russell L.
Published in Neoplasia (New York, N.Y.) (01.03.2003)
Published in Neoplasia (New York, N.Y.) (01.03.2003)
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Journal Article
Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity
Roell, Marina K., Issafras, Hassan, Bauer, Robert J., Michelson, Kristen S., Mendoza, Nerissa, Vanegas, Sandra I., Gross, Lisa M., Larsen, Paul D., Bedinger, Daniel H., Bohmann, David J., Nonet, Genevieve H., Liu, Naichi, Lee, Steve R., Handa, Masahisa, Kantak, Seema S., Horwitz, Arnold H., Hunter, John J., Owyang, Alexander M., Mirza, Amer M., Corbin, John A., White, Mark L.
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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Expression and Characterization of Cysteine-Modified Variants of an Amino-Terminal Fragment of Bactericidal/Permeability-Increasing Protein
Horwitz, Arnold H., Leigh, Scott D., Abrahamson, Susan, Gazzano-Santoro, Hélène, Liu, Pei-Syan, Williams, Robert E., Carroll, Stephen F., Theofan, Georgia
Published in Protein expression and purification (01.08.1996)
Published in Protein expression and purification (01.08.1996)
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Bactericidal/Permeability-Increasing Protein Inhibits Growth of a Strain of Acholeplasma laidlawii and L Forms of the Gram-Positive Bacteria Staphylococcus aureus andStreptococcus pyogenes
Horwitz, Arnold H, Williams, Robert E, Liu, Pei-Syan, Nadell, Rossana
Published in Antimicrobial Agents and Chemotherapy (01.09.1999)
Published in Antimicrobial Agents and Chemotherapy (01.09.1999)
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Journal Article
An Allosteric Antibody to the Leptin Receptor Reduces Body Weight and Reverses the Diabetic Phenotype in the Lep^sup ob^/Lep^sup ob^ Mouse
Bhaskar, Vinay, Goldfine, Ira D, Gerstner, Resi, Michelson, Kristen, Tran, Catarina, Nonet, Genevieve, Bohmann, David, Pongo, Elizabeth, Zhao, Jingsong, Horwitz, Arnold H, Takeuchi, Toshihiko, White, Mark, Corbin, John A
Published in Obesity (Silver Spring, Md.) (01.08.2016)
Published in Obesity (Silver Spring, Md.) (01.08.2016)
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Journal Article
An allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lep ob /Lep ob mouse
Bhaskar, Vinay, Goldfine, Ira D., Gerstner, Resi, Michelson, Kristen, Tran, Catarina, Nonet, Genevieve, Bohmann, David, Pongo, Elizabeth, Zhao, Jingsong, Horwitz, Arnold H., Takeuchi, Toshihiko, White, Mark, Corbin, John A.
Published in Obesity (Silver Spring, Md.) (01.08.2016)
Published in Obesity (Silver Spring, Md.) (01.08.2016)
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Journal Article
An allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lepob/Lepob mouse
Bhaskar, Vinay, Goldfine, Ira D., Gerstner, Resi, Michelson, Kristen, Tran, Catarina, Nonet, Genevieve, Bohmann, David, Pongo, Elizabeth, Zhao, Jingsong, Horwitz, Arnold H., Takeuchi, Toshihiko, White, Mark, Corbin, John A.
Published in Obesity (Silver Spring, Md.) (01.08.2016)
Published in Obesity (Silver Spring, Md.) (01.08.2016)
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Biochemical Characterization of Recombinant Fusions of Lipopolysaccharide Binding Protein and Bactericidal/Permeability-increasing Protein
Abrahamson, Susan L., Wu, Hsiu-Mei, Williams, Robert E., Der, Ken, Ottah, Nneka, Little, Roger, Gazzano-Santoro, Helene, Theofan, Georgia, Bauer, Robert, Leigh, Scott, Orme, Anne, Horwitz, Arnold H., Carroll, Stephen F., Dedrick, Russell L.
Published in The Journal of biological chemistry (24.01.1997)
Published in The Journal of biological chemistry (24.01.1997)
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Journal Article
Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1b Activity
Roell, Marina K, Issafras, Hassan, Bauer, Robert J, Michelson, Kristen S, Mendoza, Nerissa, Vanegas, Sandra I, Gross, Lisa M, Larsen, Paul D, Bedinger, Daniel H, Bohmann, David J, Nonet, Genevieve H, Liu, Naichi, Lee, Steve R, Handa, Masahisa, Kantak, Seema S, Horwitz, Arnold H, Hunter, John J, Owyang, Alexander M, Mirza, Amer M, Corbin, John A, White, Mark L
Published in The Journal of biological chemistry (01.07.2010)
Published in The Journal of biological chemistry (01.07.2010)
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DNA sequence of the araC regulatory gene from Escherichia coli B/r
Miyada, C.Garrett, Horwitz, Arnold H., Cass, Laura G., Timko, Josef, Wilcox, Gary
Published in Nucleic acids research (25.11.1980)
Published in Nucleic acids research (25.11.1980)
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Journal Article
Kinetic approach to pathway attenuation using XOMA 052, a regulatory therapeutic antibody that modulates interleukin-1beta activity
Roell, Marina K, Issafras, Hassan, Bauer, Robert J, Michelson, Kristen S, Mendoza, Nerissa, Vanegas, Sandra I, Gross, Lisa M, Larsen, Paul D, Bedinger, Daniel H, Bohmann, David J, Nonet, Genevieve H, Liu, Naichi, Lee, Steve R, Handa, Masahisa, Kantak, Seema S, Horwitz, Arnold H, Hunter, John J, Owyang, Alexander M, Mirza, Amer M, Corbin, John A, White, Mark L
Published in The Journal of biological chemistry (02.07.2010)
Published in The Journal of biological chemistry (02.07.2010)
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