New 3-Alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells
Nielsen, Flemming E, Ebdrup, Søren, Jensen, Anette Frost, Ynddal, Lars, Bodvarsdottir, Thora B, Stidsen, Carsten, Worsaae, Anne, Boonen, Harrie C. M, Arkhammar, Per O. G, Fremming, Tinna, Wahl, Philip, Kornø, Hanne T, Hansen, J. Bondo
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Journal Article
6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells
Nielsen, Flemming E, Bodvarsdottir, Thora B, Worsaae, Anne, MacKay, Peter, Stidsen, Carsten E, Boonen, Harrie C. M, Pridal, Lone, Arkhammar, Per O. G, Wahl, Philip, Ynddal, Lars, Junager, Finn, Dragsted, Nils, Tagmose, Tina M, Mogensen, John P, Koch, Anette, Treppendahl, Svend P, Hansen, J. Bondo
Published in Journal of medicinal chemistry (12.09.2002)
Published in Journal of medicinal chemistry (12.09.2002)
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Journal Article
Possible role of an ischemic preconditioning-like response mechanism in KATP channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function
SANDLER, Stellan, ANDERSSON, Annika K, LARSSON, Jenny, MAKEEVA, Natalia, OLSEN, Therese, ARKHAMMAR, Per O. G, HANSEN, John Bondo, ANDERS KARLSSON, F, WELSH, Nils
Published in Biochemical pharmacology (15.12.2008)
Published in Biochemical pharmacology (15.12.2008)
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Journal Article
Inhibition of Insulin Secretion as a New Drug Target in the Treatment of Metabolic Disorders
BONDO HANSEN, J, ARKHAMMAR, Per O. G, BODVARSDOTTIR, Thora B, WAHL, Philip
Published in Current medicinal chemistry (01.06.2004)
Published in Current medicinal chemistry (01.06.2004)
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Journal Article
Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function
Sandler, Stellan, Andersson, Annika K, Larsson, Jenny, Makeeva, Natalia, Olsen, Therese, Arkhammar, Per O G, Hansen, John Bondo, Karlsson, F Anders, Welsh, Nils
Published in Biochemical pharmacology (15.12.2008)
Published in Biochemical pharmacology (15.12.2008)
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Journal Article
Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels
SCHOU, Søren C, HANSEN, Holger C, LEBRUN, Philippe, HANSEN, John Bondo, TAGMOSE, Tina M, BOONEN, Harrie C. M, WORSAAE, Anne, DRABOWSKI, Michael, WAHL, Philip, ARKHAMMAR, Per O. G, BODVARSDOTTIR, Thora, ANTOINE, Marie-Hélène
Published in Bioorganic & medicinal chemistry (03.01.2005)
Published in Bioorganic & medicinal chemistry (03.01.2005)
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Journal Article
Identification of Akt Pathway Inhibitors Using Redistribution Screening on the FLIPR and the IN Cell 3000 Analyzer
Lundholt, Betina Kerstin, Linde, Viggo, Loechel, Frosty, Pedersen, Hans-Christian, Møller, Søren, Præstegaard, Morten, Mikkelsen, Ivan, Scudder, Kurt, Bjørn, Sara Petersen, Heide, Morten, Arkhammar, Per O.G., Terry, Robert, Nielsen, Søren Jensby
Published in Journal of biomolecular screening (01.02.2005)
Published in Journal of biomolecular screening (01.02.2005)
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Journal Article
Arylcyanoguanidines as Activators of Kir6.2/SUR1KATP Channels and Inhibitors of Insulin Release
Tagmose, Tina M, Schou, Søren C, Mogensen, John P, Nielsen, Flemming E, Arkhammar, Per O. G, Wahl, Philip, Hansen, Birgit S, Worsaae, Anne, Boonen, Harrie C. M, Antoine, Marie-Hélène, Lebrun, Philippe, Hansen, John Bondo
Published in Journal of medicinal chemistry (03.06.2004)
Published in Journal of medicinal chemistry (03.06.2004)
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Journal Article
Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release
Tagmose, Tina M, Schou, Søren C, Mogensen, John P, Nielsen, Flemming E, Arkhammar, Per O G, Wahl, Philip, Hansen, Birgit S, Worsaae, Anne, Boonen, Harrie C M, Antoine, Marie-Hélène, Lebrun, Philippe, Hansen, John Bondo
Published in Journal of medicinal chemistry (03.06.2004)
Published in Journal of medicinal chemistry (03.06.2004)
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Journal Article
2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels
Nielsen, Flemming E, Jacobsen, Palle, Worsaae, Anne, Arkhammar, Per O G, Wahl, Philip, Bondo Hansen, John
Published in Bioorganic & medicinal chemistry letters (06.12.2004)
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Published in Bioorganic & medicinal chemistry letters (06.12.2004)
Journal Article
New 3-Alkylamino-4 H -thieno-1,2,4-thiadiazine 1,1-Dioxide Derivatives Activate ATP-Sensitive Potassium Channels of Pancreatic Beta Cells
Nielsen, Flemming E., Ebdrup, Søren, Jensen, Anette Frost, Ynddal, Lars, Bodvarsdottir, Thora B., Stidsen, Carsten, Worsaae, Anne, Boonen, Harrie C. M., Arkhammar, Per O. G., Fremming, Tinna, Wahl, Philip, Kornø, Hanne T., Hansen, J. Bondo
Published in Journal of medicinal chemistry (01.07.2006)
Published in Journal of medicinal chemistry (01.07.2006)
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Journal Article
Dihydroxyacetone-induced Oscillations in Cytoplasmic Free Ca2+ and the ATP/ADP Ratio in Pancreatic β-Cells at Substimulatory Glucose
Juntti-Berggren, Lisa, Webb, Dominic-Luc, Arkhammar, Per O.G., Schultz, Vera, Schweda, Elke K.H., Tornheim, Keith, Berggren, Per-Olof
Published in The Journal of biological chemistry (17.10.2003)
Published in The Journal of biological chemistry (17.10.2003)
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Journal Article
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets
Maedler, Kathrin, Størling, Joachim, Sturis, Jeppe, Zuellig, Richard A, Spinas, Giatgen A, Arkhammar, Per O G, Mandrup-Poulsen, Thomas, Donath, Marc Y
Published in Diabetes (New York, N.Y.) (01.07.2004)
Published in Diabetes (New York, N.Y.) (01.07.2004)
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Journal Article
Glucose- and Interleukin-1β-Induced β-Cell Apoptosis Requires Ca2+ Influx and Extracellular Signal-Regulated Kinase (ERK) 1/2 Activation and Is Prevented by a Sulfonylurea Receptor 1/Inwardly Rectifying K+ Channel 6.2 (SUR/Kir6.2) Selective Potassium Channel Opener in Human Islets
MAEDLER, Kathrin, STØRLING, Joachim, STURIS, Jeppe, ZUELLIG, Richard A, SPINAS, Giatgen A, ARKHAMMAR, Per O. G, MANDRUP-POULSEN, Thomas, DONATH, Marc Y
Published in Diabetes (New York, N.Y.) (01.07.2004)
Published in Diabetes (New York, N.Y.) (01.07.2004)
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Journal Article
6-Chloro-3-alkylamino-4 H -thieno[3,2 -e ]-1,2,4-thiadiazine 1,1-Dioxide Derivatives Potently and Selectively Activate ATP Sensitive Potassium Channels of Pancreatic β-Cells
Nielsen, Flemming E., Bodvarsdottir, Thora B., Worsaae, Anne, MacKay, Peter, Stidsen, Carsten E., Boonen, Harrie C. M., Pridal, Lone, Arkhammar, Per O. G., Wahl, Philip, Ynddal, Lars, Junager, Finn, Dragsted, Nils, Tagmose, Tina M., Mogensen, John P., Koch, Anette, Treppendahl, Svend P., Hansen, J. Bondo
Published in Journal of medicinal chemistry (01.09.2002)
Published in Journal of medicinal chemistry (01.09.2002)
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Journal Article
Phenylcyanoguanidines as inhibitors of glucose-induced insulin secretion from beta cells
Tagmose, Tina M, Mogensen, John P, Agerholm, Pia C, Arkhammar, Per O.G, Wahl, Philip, Worsaae, Anne, Hansen, J.Bondo
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
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Journal Article
2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide Activates Kir6.2/SUR1 KATP Channels
Nielsen, Flemming E., Jacobsen, Palle, Worsaae, Anne, Arkhammar, Per O. G., Wahl, Philip, Hansen, John Bondo
Published in ChemInform (29.03.2005)
Published in ChemInform (29.03.2005)
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