Antibody-Drug Conjugates for the Treatment of Cancer
Flygare, John A., Pillow, Thomas H., Aristoff, Paul
Published in Chemical biology & drug design (01.01.2013)
Published in Chemical biology & drug design (01.01.2013)
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Journal Article
Rifamycins – Obstacles and opportunities
Aristoff, Paul A, Garcia, George A, Kirchhoff, Paul D, Hollis Showalter, H.D
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2010)
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2010)
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Journal Article
A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)
Bai, Fengwei, Asojo, Oluwatoyin A., Cirillo, Pier, Ciustea, Mihai, Ledizet, Michel, Aristoff, Paul A., Leng, Lin, Koski, Raymond A., Powell, Thomas J., Bucala, Richard, Anthony, Karen G.
Published in The Journal of biological chemistry (31.08.2012)
Published in The Journal of biological chemistry (31.08.2012)
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Journal Article
New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis
Anthony, Karen G, Strych, Ulrich, Yeung, Kacheong R, Shoen, Carolyn S, Perez, Oriana, Krause, Kurt L, Cynamon, Michael H, Aristoff, Paul A, Koski, Raymond A
Published in PloS one (26.05.2011)
Published in PloS one (26.05.2011)
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Journal Article
Inhibition of mycobacterial alanine racemase activity and growth by thiadiazolidinones
Lee, Yashang, Mootien, Sara, Shoen, Carolyn, Destefano, Michelle, Cirillo, Pier, Asojo, Oluwatoyin A., Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.
Published in Biochemical pharmacology (15.07.2013)
Published in Biochemical pharmacology (15.07.2013)
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Journal Article
Thiadiazolidinones: A new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus
Ciustea, Mihai, Mootien, Sara, Rosato, Adriana E., Perez, Oriana, Cirillo, Pier, Yeung, Kacheong R., Ledizet, Michel, Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Kaplan, Paul A., Anthony, Karen G.
Published in Biochemical pharmacology (01.02.2012)
Published in Biochemical pharmacology (01.02.2012)
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Journal Article
Antibacterial Oxazolidinones Possessing a Novel C-5 Side Chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic Acid Amide (PF-00422602), a New Lead Compound
Poel, Toni-Jo, Thomas, Richard C, Adams, Wade J, Aristoff, Paul A, Barbachyn, Michael R, Boyer, Frederick E, Brieland, Joan, Brideau, Roger, Brodfuehrer, Joanne, Brown, Alan P, Choy, Allison L, Dermyer, Michael, Dority, Michael, Ford, Charles W, Gadwood, Robert C, Hanna, Debra, Hongliang, Cai, Huband, Michael D, Huber, Christopher, Kelly, Rose, Kim, Ji-Young, Martin, Joseph P, Pagano, Paul J, Ross, Daniel, Skerlos, Laura, Sulavik, Mark C, Zhu, Tong, Zurenko, Gary E, Prasad, J. V. N. Vara
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
Oxazolidinones: a new class of antibacterials
Zurenko, Gary E, Gibson, John K, Shinabarger, Dean L, Aristoff, Paul A, Ford, Charles W, Tarpley, W.Gary
Published in Current Opinion in Pharmacology (01.10.2001)
Published in Current Opinion in Pharmacology (01.10.2001)
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Book Review
Journal Article
Synthesis and biological evaluation of benzazepine oxazolidinone antibacterials
Johnson, Paul D., Aristoff, Paul A., Zurenko, Gary E., Schaadt, Ronda D., Yagi, Betty H., Ford, Charles W., Hamel, Judith C., Stapert, Douglas, Moerman, Judy K.
Published in Bioorganic & medicinal chemistry letters (01.12.2003)
Published in Bioorganic & medicinal chemistry letters (01.12.2003)
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Journal Article
Structure–Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch
Vicens, Quentin, Mondragón, Estefanía, Reyes, Francis E, Coish, Philip, Aristoff, Paul, Berman, Judd, Kaur, Harpreet, Kells, Kevin W, Wickens, Phil, Wilson, Jeffery, Gadwood, Robert C, Schostarez, Heinrich J, Suto, Robert K, Blount, Kenneth F, Batey, Robert T
Published in ACS chemical biology (19.10.2018)
Published in ACS chemical biology (19.10.2018)
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Journal Article
Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora
Blount, Kenneth F, Megyola, Cynthia, Plummer, Mark, Osterman, David, O'Connell, Tim, Aristoff, Paul, Quinn, Cheryl, Chrusciel, R Alan, Poel, Toni J, Schostarez, Heinrich J, Stewart, Catherine A, Walker, Daniel P, Wuts, Peter G M, Breaker, Ronald R
Published in Antimicrobial agents and chemotherapy (01.09.2015)
Published in Antimicrobial agents and chemotherapy (01.09.2015)
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Journal Article
Molecular basis for sequence-specific DNA alkylation by CC-1065
Hurley, Laurence H, Lee, Chong Soon, McGovren, J. Patrick, Warpehoski, Martha A, Mitchell, Mark A, Kelly, Robert C, Aristoff, Paul A
Published in Biochemistry (Easton) (17.05.1988)
Published in Biochemistry (Easton) (17.05.1988)
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Journal Article
Structure-activity relationship of flavin analogs that target the FMN riboswitch
Vicens, Quentin, Mondragón, Estefanía, Reyes, Francis E., Coish, Philip, Aristoff, Paul, Berman, Judd, Kaur, Harpreet, Kells, Kevin W., Wickens, Phil, Wilson, Jeffery, Gadwood, Robert C., Schostarez, Heinrich J., Suto, Robert K., Blount, Kenneth F., Batey, Robert T.
Published in ACS chemical biology (20.09.2018)
Published in ACS chemical biology (20.09.2018)
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Journal Article
Coupling of cyclopropapyrroloindole (CPI) derivatives. The preparation of CC-1065, ent-CC-1065, and analogs
Kelly, Robert C, Gebhard, Ilse, Wicnienski, Nancy, Aristoff, Paul A, Johnson, Paul D, Martin, David G
Published in Journal of the American Chemical Society (01.10.1987)
Published in Journal of the American Chemical Society (01.10.1987)
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Journal Article