Search Results - "ARAKI KAZUSHI" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

by Yamagishi, Makoto, Hori, Makoto, Fujikawa, Dai, Ohsugi, Takeo, Honma, Daisuke, Adachi, Nobuaki, Katano, Harutaka, Hishima, Tsunekazu, Kobayashi, Seiichiro, Nakano, Kazumi, Nakashima, Makoto, Iwanaga, Masako, Utsunomiya, Atae, Tanaka, Yuetsu, Okada, Seiji, Tsukasaki, Kunihiro, Tobinai, Kensei, Araki, Kazushi, Watanabe, Toshiki, Uchimaru, Kaoru
Published in Cell reports (Cambridge) (19.11.2019)

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Journal Article

CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib

CDKN1C‐mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib

by Kagiyama, Yuki, Fujita, Shuhei, Shima, Yutaka, Yamagata, Kazutsune, Katsumoto, Takuo, Nakagawa, Makoto, Honma, Daisuke, Adachi, Nobuaki, Araki, Kazushi, Kato, Ayako, Inaki, Koichiro, Ono, Yoshimasa, Fukuhara, Suguru, Kobayashi, Yukio, Tobinai, Kensei, Kitabayashi, Issay
Published in Cancer science (01.06.2021)

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Journal Article

Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma

Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma

by Nakagawa, Makoto, Fujita, Shuhei, Katsumoto, Takuo, Yamagata, Kazutsune, Ogawara, Yoko, Hattori, Ayuna, Kagiyama, Yuki, Honma, Daisuke, Araki, Kazushi, Inoue, Tatsuya, Kato, Ayako, Inaki, Koichiro, Wada, Chisa, Ono, Yoshimasa, Yamamoto, Masahide, Miura, Osamu, Nakashima, Yasuharu, Kitabayashi, Issay
Published in Cancer science (01.01.2019)

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IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia

IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia

by Ogawara, Yoko, Katsumoto, Takuo, Aikawa, Yukiko, Shima, Yutaka, Kagiyama, Yuki, Soga, Tomoyoshi, Matsunaga, Hironori, Seki, Takahiko, Araki, Kazushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (15.05.2015)

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Journal Article

EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy

EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy

by Koseki, Akihito, Araya, Natsumi, Yamagishi, Makoto, Yamauchi, Junji, Yagishita, Naoko, Takao, Naoki, Takahashi, Katsunori, Kunitomo, Yasuo, Honma, Daisuke, Araki, Kazushi, Uchimaru, Kaoru, Sato, Tomoo, Yamano, Yoshihisa
Published in Frontiers in microbiology (12.06.2023)

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Journal Article

Structure–Activity Relationship Studies of 3- or 4‑Pyridine Derivatives of DS-6930

Structure–Activity Relationship Studies of 3- or 4‑Pyridine Derivatives of DS-6930

by Shinozuka, Tsuyoshi, Tsukada, Tomoharu, Fujii, Kunihiko, Tokumaru, Eri, Matsui, Yumi, Wakimoto, Satoko, Ogata, Tsuneaki, Araki, Kazushi, Sawamura, Ryoko, Watanabe, Nobuaki, Mori, Makoto, Tanaka, Jun
Published in ACS medicinal chemistry letters (14.03.2019)

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Journal Article

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

by Yamagishi, Makoto, Hori, Makoto, Fujikawa, Dai, Honma, Daisuke, Adachi, Nobuaki, Ohsugi, Takeo, Nakano, Kazumi, Nakashima, Makoto, Kobayashi, Seiichiro, Iwanaga, Masako, Utsunomiya, Atae, Okada, Seiji, Tsukasaki, Kunihiro, Tobinai, Kensei, Araki, Kazushi, Watanabe, Toshiki, Uchimaru, Kaoru
Published in Blood (02.12.2016)

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Journal Article

Role of Rho-kinase in regulation of insulin action and glucose homeostasis

Role of Rho-kinase in regulation of insulin action and glucose homeostasis

by Furukawa, Noboru, Ongusaha, Pat, Jahng, Wan Jin, Araki, Kazushi, Choi, Cheol Soo, Kim, Hyo-Jeong, Lee, Yong Hee, Kaibuchi, Kozo, Kahn, Barbara B., Masuzaki, Hiroaki, Kim, Jason K., Lee, Sam W., Kim, Young-Bum
Published in Cell metabolism (01.08.2005)

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Journal Article

Potent Antidiabetic Effects of Rivoglitazone, a Novel Peroxisome Proliferator–Activated Receptor-γ Agonist, in Obese Diabetic Rodent Models

Potent Antidiabetic Effects of Rivoglitazone, a Novel Peroxisome Proliferator–Activated Receptor-γ Agonist, in Obese Diabetic Rodent Models

by Kanda, Shoichi, Nakashima, Ryutaro, Takahashi, Kanako, Tanaka, Jun, Ogawa, Junko, Ogata, Tsuneaki, Yachi, Makoto, Araki, Kazushi, Ohsumi, Jun
Published in Journal of Pharmacological Sciences (2009)

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Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor γ Ligand, Cerco-A

Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor γ Ligand, Cerco-A

by Wakabayashi, Kenji, Hayashi, Shinko, Matsui, Yumi, Matsumoto, Takuo, Furukawa, Akihiro, Kuroha, Masanori, Tanaka, Naomi, Inaba, Tomoko, Kanda, Shoichi, Tanaka, Jun, Okuyama, Ryo, Wakimoto, Satoko, Ogata, Tsuneaki, Araki, Kazushi, Ohsumi, Jun
Published in Biological & pharmaceutical bulletin (2011)

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Journal Article

Identification of Molecular Target of AMP-activated Protein Kinase Activator by Affinity Purification and Mass Spectrometry

Identification of Molecular Target of AMP-activated Protein Kinase Activator by Affinity Purification and Mass Spectrometry

by Kosaka, Toshiyuki, Okuyama, Ryo, Sun, Weiyong, Ogata, Tsuneaki, Harada, Jun, Araki, Kazushi, Izumi, Masanori, Yoshida, Taishi, Okuno, Akira, Fujiwara, Toshihiko, Ohsumi, Jun, Ichikawa, Kimihisa
Published in Analytical chemistry (Washington) (01.04.2005)

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Journal Article

Abstract 4670: Identification of a possible therapeutic candidate for multiple myeloma based on dual inhibition of EZH1/EZH2

Abstract 4670: Identification of a possible therapeutic candidate for multiple myeloma based on dual inhibition of EZH1/EZH2

by Nakagawa, Makoto, Fujita, Shuhei, Honma, Daisuke, Araki, Kazushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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Journal Article

Abstract 4672: Novel epigenetic approach to relapsed mantle cell lymphoma based on dual inhibition of EZH1/EZH2

Abstract 4672: Novel epigenetic approach to relapsed mantle cell lymphoma based on dual inhibition of EZH1/EZH2

by Fujita, Shuhei, Kagiyama, Yuki, Honma, Daisuke, Adachi, Nobuaki, Araki, Kazushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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Journal Article

Abstract 913: Novel leukemia stem cell-targeted therapy for acute myeloid leukemia based on dual inhibition of EZH1/EZH2

Abstract 913: Novel leukemia stem cell-targeted therapy for acute myeloid leukemia based on dual inhibition of EZH1/EZH2

by Fujita, Shuhei, Honma, Daisuke, Araki, Kazushi, Aoyama, Kazumasa, Iwama, Atsushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Journal Article

Abstract 3101: The mutant IDH1 inhibitor prevents growth of glioblastoma with IDH1 mutation in patient-derived xenograft (PDX) model

Abstract 3101: The mutant IDH1 inhibitor prevents growth of glioblastoma with IDH1 mutation in patient-derived xenograft (PDX) model

by Machida, Yukino, Ogawara, Yoko, Ichimura, Koichi, Matsunaga, Hironori, Takahiko, Seki, Araki, Kazushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Journal Article

Abstract 913: Novel leukemia stem cell-targeted therapy for acute myeloid leukemia based on dual inhibition of EZH1EZH2

Abstract 913: Novel leukemia stem cell-targeted therapy for acute myeloid leukemia based on dual inhibition of EZH1EZH2

by Fujita, Shuhei, Honma, Daisuke, Araki, Kazushi, Aoyama, Kazumasa, Iwama, Atsushi, Kitabayashi, Issay
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Journal Article

$First-in-Human Study of the EZH1/2 Dual Inhibitor Valemetostat in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) - Updated Results Focusing on Adult T-Cell Leukemia-Lymphoma (ATL)$

First-in-Human Study of the EZH1/2 Dual Inhibitor Valemetostat in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) - Updated Results Focusing on Adult T-Cell Leukemia-Lymphoma (ATL)

by Morishima, Satoko, Ishitsuka, Kenji, Izutsu, Koji, Kusumoto, Shigeru, Makiyama, Junya, Utsunomiya, Atae, Nosaka, Kisato, Ishida, Takashi, Imaizumi, Yoshitaka, Yamauchi, Nobuhiko, Araki, Kazushi, Adachi, Nobuaki, Yamashita, Tomonari, Atsumi, Ryo, Tsukasaki, Kunihiro, Tobinai, Kensei
Published in Blood (13.11.2019)

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Journal Article

Discovery of DS-6930, a potent selective PPARγ modulator. Part I: Lead identification

Discovery of DS-6930, a potent selective PPARγ modulator. Part I: Lead identification

by Shinozuka, Tsuyoshi, Tsukada, Tomoharu, Fujii, Kunihiko, Tokumaru, Eri, Shimada, Kousei, Onishi, Yoshiyuki, Matsui, Yumi, Wakimoto, Satoko, Kuroha, Masanori, Ogata, Tsuneaki, Araki, Kazushi, Ohsumi, Jun, Sawamura, Ryoko, Watanabe, Nobuaki, Yamamoto, Hideki, Fujimoto, Kazunori, Tani, Yoshiro, Mori, Makoto, Tanaka, Jun
Published in Bioorganic & medicinal chemistry (01.10.2018)

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Journal Article

HTLV-1 관련 척수증을 치료하는 것에 사용하기 위한 의약 조성물

HTLV-1 관련 척수증을 치료하는 것에 사용하기 위한 의약 조성물

by ARAKI KAZUSHI, UEDA NATSUMI, YAMANO YOSHIHISA
Year of Publication 17.09.2019

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Patent

Novel Leukemia Stem Cell-Targeted Therapy for Acute Myeloid Leukemia Based on Dual Inhibition of Ezh1/Ezh2

Novel Leukemia Stem Cell-Targeted Therapy for Acute Myeloid Leukemia Based on Dual Inhibition of Ezh1/Ezh2

by Fujita, Shuhei, Honma, Daisuke, Adachi, Nobuaki, Araki, Kazushi, Takamatsu, Emi, Aoyama, Kazumasa, Iwama, Atsushi, Kitabayashi, Issay
Published in Blood (03.12.2015)

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Journal Article

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