Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials
Berry-Kravis, Elizabeth, Des Portes, Vincent, Hagerman, Randi, Jacquemont, Sébastien, Charles, Perrine, Visootsak, Jeannie, Brinkman, Marc, Rerat, Karin, Koumaras, Barbara, Zhu, Liansheng, Barth, Gottfried Maria, Jaecklin, Thomas, Apostol, George, von Raison, Florian
Published in Science translational medicine (13.01.2016)
Published in Science translational medicine (13.01.2016)
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The challenges of clinical trials in fragile X syndrome
Jacquemont, Sébastien, Berry-Kravis, Elizabeth, Hagerman, Randi, von Raison, Florian, Gasparini, Fabrizio, Apostol, George, Ufer, Mike, Des Portes, Vincent, Gomez-Mancilla, Baltazar
Published in Psychopharmacology (01.03.2014)
Published in Psychopharmacology (01.03.2014)
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Mavoglurant in Fragile X Syndrome: Results of two open-label, extension trials in adults and adolescents
Hagerman, Randi, Jacquemont, Sebastien, Berry-Kravis, Elizabeth, Des Portes, Vincent, Stanfield, Andrew, Koumaras, Barbara, Rosenkranz, Gerd, Murgia, Alessandra, Wolf, Christian, Apostol, George, von Raison, Florian
Published in Scientific reports (19.11.2018)
Published in Scientific reports (19.11.2018)
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Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures
Kao, Chester J, Charmsaz, Soren, Alden, Stephanie L, Brancati, Madelena, Li, Howard L, Balaji, Aanika, Munjal, Kabeer, Howe, Kathryn, Mitchell, Sarah, Leatherman, James, Griffin, Ervin, Nakazawa, Mari, Tsai, Hua-Ling, Danilova, Ludmila, Thoburn, Chris, Gizzi, Jennifer, Gross, Nicole E, Hernandez, Alexei, Coyne, Erin M, Shin, Sarah M, Babu, Jayalaxmi Suresh, Apostol, George W, Durham, Jennifer, Christmas, Brian J, Konig, Maximilian F, Lipson, Evan J, Naidoo, Jarushka, Cappelli, Laura C, Pabani, Aliyah, Ged, Yasser, Baretti, Marina, Brahmer, Julie, Hoffman-Censits, Jean, Seiwert, Tanguy Y, Garonce-Hediger, Rachel, Guha, Aditi, Bansal, Sanjay, Tang, Laura, Jaffee, Elizabeth M, Chandler, G Scott, Mohindra, Rajat, Ho, Won Jin, Yarchoan, Mark
Published in The Journal of clinical investigation (29.08.2024)
Published in The Journal of clinical investigation (29.08.2024)
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Longitudinal association of body mass index with lung function: the CARDIA study
Thyagarajan, Bharat, Jacobs, Jr, David R, Apostol, George G, Smith, Lewis J, Jensen, Robert L, Crapo, Robert O, Barr, R Graham, Lewis, Cora E, Williams, O Dale
Published in Respiratory research (04.04.2008)
Published in Respiratory research (04.04.2008)
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Development of mavoglurant and its potential for the treatment of fragile X syndrome
Gomez-Mancilla, Baltazar, Berry-Kravis, Elizabeth, Hagerman, Randi, von Raison, Florian, Apostol, George, Ufer, Mike, Gasparini, Fabrizio, Jacquemont, Sébastien
Published in Expert opinion on investigational drugs (01.01.2014)
Published in Expert opinion on investigational drugs (01.01.2014)
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Plasma fibrinogen and lung function: the CARDIA Study
Thyagarajan, Bharat, Jacobs, David R, Apostol, George G, Smith, Lewis J, Lewis, Cora E, Williams, O Dale
Published in International journal of epidemiology (01.08.2006)
Published in International journal of epidemiology (01.08.2006)
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Safety and Efficacy of ABT-089 in Pediatric Attention-Deficit/Hyperactivity Disorder: Results from Two Randomized Placebo-Controlled Clinical Trials
Wilens, Timothy E., M.D, Gault, Laura M., M.D., Ph.D, Childress, Ann, M.D, Kratochvil, Christopher J., M.D, Bensman, Lindsey, B.S, Hall, Coleen M., M.S, Olson, Evelyn, B.S, Robieson, Weining Z., Ph.D, Garimella, Tushar S., Ph.D, Abi-Saab, Walid M., M.D, Apostol, George, M.D, Saltarelli, Mario D., M.D., Ph.D
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01.01.2011)
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01.01.2011)
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Divalproex Extended-Release in Adolescent Migraine Prophylaxis: Results of a Randomized, Double-Blind, Placebo-Controlled Study
Apostol, George, Cady, Roger K., Laforet, Genevieve A., Robieson, Weining Z., Olson, Evelyn, Abi-Saab, Walid M., Saltarelli, Mario
Published in Headache (01.07.2008)
Published in Headache (01.07.2008)
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Early Life Factors Contribute to the Decrease in Lung Function between Ages 18 and 40: The Coronary Artery Risk Development in Young Adults Study
Apostol, George G, Jacobs, David R., Jr, Tsai, Albert W, Crow, Richard S, Williams, O. Dale, Townsend, Mary C, Beckett, William S
Published in American journal of respiratory and critical care medicine (15.07.2002)
Published in American journal of respiratory and critical care medicine (15.07.2002)
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Safety and Tolerability of Divalproex Sodium Extended-Release in the Prophylaxis of Migraine Headaches: Results of an Open-Label Extension Trial in Adolescents
Apostol, George, Pakalnis, Ann, Laforet, Genevieve A., Robieson, Weining Z., Olson, Evelyn, Abi-Saab, Walid M., Saltarelli, Mario
Published in Headache (01.01.2009)
Published in Headache (01.01.2009)
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Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome
Berry-Kravis, Elizabeth M., Lindemann, Lothar, Jønch, Aia E., Apostol, George, Bear, Mark F., Carpenter, Randall L., Crawley, Jacqueline N., Curie, Aurore, Des Portes, Vincent, Hossain, Farah, Gasparini, Fabrizio, Gomez-Mancilla, Baltazar, Hessl, David, Loth, Eva, Scharf, Sebastian H., Wang, Paul P., Von Raison, Florian, Hagerman, Randi, Spooren, Will, Jacquemont, Sébastien
Published in Nature reviews. Drug discovery (01.04.2018)
Published in Nature reviews. Drug discovery (01.04.2018)
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0593 Functional Outcomes of Sleep Questionnaire in a phase 2 study of mazindol ER in narcolepsy
Bogan, Richard, Stern, Thomas, Corser, Bruce, Franco, Jennifer, Konofal, Eric, Apostol, George, Morse, Anne, Rosenberg, Russell, Thorpy, Michael, Kushida, Clete
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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0585 A four-week randomized, double-blind, placebo-controlled, phase 2 study of mazindol ER in the treatment of narcolepsy
Corser, Bruce, Stern, Thomas, Bogan, Richard, Franco, Jennifer, Apostol, George, Konofal, Eric, Morse, Anne, Rosenberg, Russell, Kushida, Clete, Thorpy, Michael
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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0595 Long-term efficacy on cataplexy attacks and excessive daytime sleepiness in open-label extension study (NLS-1022) of mazindol ER
Stern, Thomas, Corser, Bruce, Bogan, Richard, Franco, Jennifer, Konofal, Eric, Apostol, George, Rosenberg, Russell, Morse, Anne, Thorpy, Michael, Kushida, Clete
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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0578 Clinician and Patient Global Impression in a Phase 2 Study of Mazindol (NLS-1021) in Adults with Narcolepsy Type 1 and Type 2
Bogan, Richard, Stern, Thomas, Corser, Bruce, Franco, Jennifer, Konofal, Eric, Apostol, George, Morse, Anne, Kushida, Clete, Thorpy, Michael, Rosenberg, Russell
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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0025 Effects of NLS-4 (Lauflumide) and modafinil in a rat model of circadian rhythm and chronic severe fatigue
Bizot, Jean-Charles, Massé, Fabienne, Combeau, Julie, Lacerda-Queiroz, Norinne, David, Sabrina, Benel, Laurent, Apostol, George, Konofal, Eric
Published in Sleep (New York, N.Y.) (29.05.2023)
Published in Sleep (New York, N.Y.) (29.05.2023)
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A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of α4β2 Agonist ABT-894 in Adults with ADHD
BAIN, Earle E, ROBIESON, Weining, PRITCHETT, Yili, GARIMELLA, Tushar, ABI-SAAB, Walid, APOSTOL, George, MCGOUGH, James J, SALTARELLI, Mario D
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2013)
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2013)
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A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of alpha 4 beta 2 Agonist ABT-894 in Adults with ADHD
Bain, Earle E, Robieson, Weining, Pritchett, Yili, Garimella, Tushar, Abi-Saab, Walid, Apostol, George, McGough, James J, Saltarelli, Mario D
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2013)
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2013)
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A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis
Mayo, Marlyn J., Pockros, Paul J., Jones, David, Bowlus, Christopher L., Levy, Cynthia, Patanwala, Imran, Bacon, Bruce, Luketic, Velimir, Vuppalanchi, Raj, Medendorp, Sharon, Dorenbaum, Alejandro, Kennedy, Ciara, Novak, Patricia, Gu, Joan, Apostol, George, Hirschfield, Gideon M.
Published in Hepatology communications (01.03.2019)
Published in Hepatology communications (01.03.2019)
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