Loading…
A review of APC somatic mosaicism and specific APC variants - I1307K and promotor variants
Shur, Shira, Sommer, Anna K., Latchford, Andrew, Spier, Isabel, Katz, Lior H.
Published in Familial cancer (16.04.2025)
Published in Familial cancer (16.04.2025)
Get full text
Journal Article
Loading…
Recurrent Mutations in APC and CTNNB1 and Activated Wnt/β-catenin Signaling in Intraductal Papillary Neoplasms of the Bile Duct: A Whole Exome Sequencing Study
Fujikura, Kohei, Akita, Masayuki, Ajiki, Tetsuo, Fukumoto, Takumi, Itoh, Tomoo, Zen, Yoh
Published in The American journal of surgical pathology (01.12.2018)
Published in The American journal of surgical pathology (01.12.2018)
Get more information
Journal Article
Loading…
E3 ubiquitin ligase APC/CCdh1 regulates SLC35F2 protein turnover and inhibits cancer progression in HeLa cells
Colaco, Jencia Carminha, Chandrasekaran, Arun Pandian, Karapurkar, Janardhan Keshav, Gowda, D.A. Ayush, Birappa, Girish, Rajkumar, Sripriya, Suresh, Bharathi, Ko, Nare, Hong, Seok-Ho, Oh, Seung Jun, Kim, Kye-Seong, Ramakrishna, Suresh
Published in Biochimica et biophysica acta. General subjects (01.11.2023)
Published in Biochimica et biophysica acta. General subjects (01.11.2023)
Get full text
Journal Article
Loading…
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1
Herrero-Mendez, Angel, Almeida, Angeles, Fernández, Emilio, Maestre, Carolina, Moncada, Salvador, Bolaños, Juan P.
Published in Nature cell biology (01.06.2009)
Published in Nature cell biology (01.06.2009)
Get full text
Journal Article
Loading…
Loading…
Association of APC I1307K and E1317Q polymorphisms with colorectal cancer among Egyptian subjects
Abdel-Malak, Camelia, Darwish, Hossam, Elsaid, Afaf, El-Tarapely, Fatma, Elshazli, Rami
Published in Familial cancer (01.01.2016)
Published in Familial cancer (01.01.2016)
Get full text
Journal Article
Loading…
Loading…
CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
Wouters, Valérie M., Helderman, Roxan F. C. P. A., Cameron, Kate, van der Hooff, Sander R., Torang, Arezo, van den Bergh, Saskia, Jackstadt, Rene, Sansom, Owen J., van Neerven, Sanne M., Medema, Jan Paul
Published in Oncogene (07.07.2025)
Published in Oncogene (07.07.2025)
Get full text
Journal Article
Loading…
T cell migration and effector function differences in familial adenomatous polyposis patients with APC gene mutations
Cuche, Céline, Mastrogiovanni, Marta, Juzans, Marie, Laude, Hélène, Ungeheuer, Marie-Noëlle, Krentzel, Daniel, Gariboldi, Maria Isabella, Scott-Algara, Daniel, Madec, Marianne, Goyard, Sophie, Floch, Camille, Chauveau-Le Friec, Gaëlle, Lafaye, Pierre, Renaudat, Charlotte, Le Bidan, Muriel, Micallef, Christine, Schmutz, Sandrine, Mella, Sébastien, Novault, Sophie, Hasan, Milena, Duffy, Darragh, Di Bartolo, Vincenzo, Alcover, Andrés
Published in Frontiers in immunology (18.07.2023)
Published in Frontiers in immunology (18.07.2023)
Get full text
Journal Article
Loading…
Spectrum of APC and MUTYH germ‐line mutations in Russian patients with colorectal malignancies
Yanus, G.A., Akhapkina, T.A., Ivantsov, A.O., Preobrazhenskaya, E.V., Aleksakhina, S.N., Bizin, I.V., Sokolenko, A.P., Mitiushkina, N.V., Kuligina, E.Sh, Suspitsin, E.N., Venina, A.R., Holmatov, M.M., Zaitseva, O.A., Yatsuk, O.S., Pashkov, D.V., Belyaev, A.M., Togo, A.V., Imyanitov, E.N., Iyevleva, A.G.
Published in Clinical genetics (01.05.2018)
Published in Clinical genetics (01.05.2018)
Get full text
Journal Article
Loading…
Loading…
Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers
Lyden, Patrick, Levy, Howard, Weymer, Sara, Pryor, Kent, Kramer, William, Griffin, John H, Davis, Thomas P, Zlokovic, Berislav
Published in Current pharmaceutical design (2013)
Published in Current pharmaceutical design (2013)
Get more information
Journal Article
Loading…
APC/Cdh1 targets PECAM‐1 for ubiquitination and degradation in endothelial cells
Liu, Jia, Yao, Qinyu, Xiao, Lei, Li, Fan, Ma, Wen, Zhang, Zihui, Xie, Xinya, Yang, Chunmiao, Cui, Qi, Tian, Ying, Zhang, Chao, Lai, Baochang, Wang, Nanping
Published in Journal of cellular physiology (01.03.2020)
Published in Journal of cellular physiology (01.03.2020)
Get full text
Journal Article
Loading…
Phase 1B trial of ADI-PEG 20 (A) plus nab-Paclitaxel (nab-P) and gemcitabine (gem) in subjects with advanced pancreatic cancer (APC)
Lowery, Maeve Aine, Capanu, Marinela, Glassman, Danielle C., Covington, Christina M., Gluskin, Jill, Brenner, Robin, Li, Chien-Feng, Bomalaski, John S., Johnston, Amanda, Barba, Adalberto, Yu, Kenneth H., Kelsen, David Paul, Abou-Alfa, Ghassan K., Saltz, Leonard, O'Reilly, Eileen Mary
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
Get full text
Journal Article
Loading…
APC mutations are common in adenomas but infrequent in adenocarcinomas of the non-ampullary duodenum
Ishizu, Kenichi, Hashimoto, Taiki, Naka, Tomoaki, Yatabe, Yasushi, Kojima, Motohiro, Kuwata, Takeshi, Nonaka, Satoru, Oda, Ichiro, Esaki, Minoru, Kudo, Masashi, Gotohda, Naoto, Yoshida, Teruhiko, Yoshikawa, Takaki, Sekine, Shigeki
Published in Journal of gastroenterology (01.11.2021)
Published in Journal of gastroenterology (01.11.2021)
Get full text
Journal Article
Loading…
Molecular Detection of APC, K‐ras, and p53 Mutations in the Serum of Colorectal Cancer Patients as Circulating Biomarkers
Wang, Jaw‐Yuan, Hsieh, Jan‐Sing, Chang, Mei‐Yin, Huang, Tsung‐Jen, Chen, Fang‐Ming, Cheng, Tian‐Lu, Alexandersen, Ketil, Huang, Yu‐Sheng, Tzou, Wen‐Shyong, Lin, Shiu‐Ru
Published in World journal of surgery (01.07.2004)
Published in World journal of surgery (01.07.2004)
Get full text
Journal Article
Loading…
The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Case-control study and meta-analysis
Rehak, Matus, Rehak, Jiri, Müller, Marc, Faude, Susanne, Faude, Frank, Siegemund, Annelie, Krcova, Vera, Slavik, Ludek, Hasenclever, Dirk, Scholz, Markus, Wiedemann, Peter
Published in Thrombosis and haemostasis (01.05.2008)
Published in Thrombosis and haemostasis (01.05.2008)
Get more information
Journal Article
Loading…
Somatic APC mosaicism and oligogenic inheritance in genetically unsolved colorectal adenomatous polyposis patients
Ciavarella, Michele, Miccoli, Sara, Prossomariti, Anna, Pippucci, Tommaso, Bonora, Elena, Buscherini, Francesco, Palombo, Flavia, Zuntini, Roberta, Balbi, Tiziana, Ceccarelli, Claudio, Bazzoli, Franco, Ricciardiello, Luigi, Turchetti, Daniela, Piazzi, Giulia
Published in European journal of human genetics : EJHG (01.03.2018)
Published in European journal of human genetics : EJHG (01.03.2018)
Get full text
Journal Article
Loading…
Evaluation of GSTP1 and APC methylation as indicators for repeat biopsy in a high‐risk cohort of men with negative initial prostate biopsies
Trock, Bruce J., Brotzman, Michelle J., Mangold, Leslie A., Bigley, Joseph W., Epstein, Jonathan I., McLeod, David, Klein, Eric A., Jones, J. Stephen, Wang, Songbai, McAskill, Theresa, Mehrotra, Jyoti, Raghavan, Bhargavi, Partin, Alan W.
Published in BJU international (01.07.2012)
Published in BJU international (01.07.2012)
Get full text
Journal Article
Loading…
The APC I1307K allele conveys a significant increased risk for cancer
Leshno, Ari, Shapira, Shiran, Liberman, Eliezer, Kraus, Sarah, Sror, Miri, Harlap‐Gat, Amira, Avivi, Doran, Galazan, Lior, David, Maayan, Maharshak, Nitsan, Moanis, Serhan, Arber, Nadir, Moshkowitz, Menachem
Published in International journal of cancer (15.03.2016)
Published in International journal of cancer (15.03.2016)
Get full text
Journal Article