Granulocyte–macrophage colony-stimulating factor primes interleukin-13 production by macrophages via protease-activated receptor-2
Aoki, Manabu, Yamaguchi, Rui, Yamamoto, Takatoshi, Ishimaru, Yasuji, Ono, Tomomichi, Sakamoto, Arisa, Narahara, Shinji, Sugiuchi, Hiroyuki, Hirose, Eiji, Yamaguchi, Yasuo
Published in Blood cells, molecules, & diseases (01.04.2015)
Published in Blood cells, molecules, & diseases (01.04.2015)
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Nationwide multi-institutional retrospective analysis of high-dose-rate brachytherapy combined with external beam radiotherapy for localized prostate cancer: An Asian Prostate HDR-BT Consortium
Ishiyama, Hiromichi, Kamitani, Nobuhiko, Kawamura, Hidemasa, Kato, Shingo, Aoki, Manabu, Kariya, Shinji, Matsumura, Taisei, Kaidu, Motoki, Yoshida, Ken, Hashimoto, Yaichiro, Noda, Yasutaka, Lim, Keith H.C, Kawase, Takatsugu, Takahashi, Takeo, Inaba, Koji, Kumano, Motoyasu, Yoshikawa, Nobuhiko, Yoshioka, Yasuo, Nakamura, Katsumasa, Hiratsuka, Junichi, Itami, Jun, Hayakawa, Kazushige
Published in Brachytherapy (01.05.2017)
Published in Brachytherapy (01.05.2017)
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Mechanism of tissue factor production by monocytes stimulated with neutrophil elastase
Kawata, Jin, Aoki, Manabu, Ishimaru, Yasuji, Ono, Tomomichi, Sagara, Katsurou, Narahara, Shinji, Matsmoto, Tamami, Hirose, Eiji, Yamaguchi, Yasuo
Published in Blood cells, molecules, & diseases (01.02.2015)
Published in Blood cells, molecules, & diseases (01.02.2015)
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Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex
Ghosh, Arun K., Brindisi, Margherita, Nyalapatla, Prasanth R., Takayama, Jun, Ella-Menye, Jean-Rene, Yashchuk, Sofiya, Agniswamy, Johnson, Wang, Yuan-Fang, Aoki, Manabu, Amano, Masayuki, Weber, Irene T., Mitsuya, Hiroaki
Published in Bioorganic & medicinal chemistry (01.10.2017)
Published in Bioorganic & medicinal chemistry (01.10.2017)
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Raltegravir blocks the infectivity of red-fluorescent-protein (mCherry)-labeled HIV-1 JR-FL in the setting of post-exposure prophylaxis in NOD/SCID/Jak3 -/- mice transplanted with human PBMCs
Ogata-Aoki, Hiromi, Higashi-Kuwata, Nobuyo, Hattori, Shin-Ichiro, Hayashi, Hironori, Danish, Matthew, Aoki, Manabu, Shiotsu, Chiemi, Hashiguchi, Yumi, Hamada, Akinobu, Kobayashi, Hisataka, Ihn, Hironobu, Okada, Seiji, Mitsuya, Hiroaki
Published in Antiviral research (01.01.2018)
Published in Antiviral research (01.01.2018)
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Design, Synthesis, Biological Evaluation, and X‐ray Studies of HIV‐1 Protease Inhibitors with Modified P2′ Ligands of Darunavir
Ghosh, Arun K., Fyvie, W. Sean, Brindisi, Margherita, Steffey, Melinda, Agniswamy, Johnson, Wang, Yuan‐Fang, Aoki, Manabu, Amano, Masayuki, Weber, Irene T., Mitsuya, Hiroaki
Published in ChemMedChem (07.12.2017)
Published in ChemMedChem (07.12.2017)
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Design of HIV‑1 Protease Inhibitors with Amino-bis-tetrahydrofuran Derivatives as P2-Ligands to Enhance Backbone-Binding Interactions: Synthesis, Biological Evaluation, and Protein–Ligand X‑ray Studies
Ghosh, Arun K., Martyr, Cuthbert D., Osswald, Heather L., Sheri, Venkat Reddy, Kassekert, Luke A., Chen, Shujing, Agniswamy, Johnson, Wang, Yuan-Fang, Hayashi, Hironori, Aoki, Manabu, Weber, Irene T., Mitsuya, Hiroaki
Published in Journal of medicinal chemistry (10.09.2015)
Published in Journal of medicinal chemistry (10.09.2015)
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Raltegravir blocks the infectivity of red-fluorescent-protein (mCherry)-labeled HIV-1JR-FL in the setting of post-exposure prophylaxis in NOD/SCID/Jak3−/− mice transplanted with human PBMCs
Ogata-Aoki, Hiromi, Higashi-Kuwata, Nobuyo, Hattori, Shin-ichiro, Hayashi, Hironori, Danish, Matthew, Aoki, Manabu, Shiotsu, Chiemi, Hashiguchi, Yumi, Hamada, Akinobu, Kobayashi, Hisataka, Ihn, Hironobu, Okada, Seiji, Mitsuya, Hiroaki
Published in Antiviral research (13.01.2018)
Published in Antiviral research (13.01.2018)
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GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants
Aoki, Manabu, Aoki-Ogata, Hiromi, Bulut, Haydar, Hayashi, Hironori, Takamune, Nobutoki, Kishimoto, Naoki, Tanaka, Hiroki, Higashi-Kuwata, Nobuyo, Hattori, Shin-Ichiro, Das, Debananda, Venkateswara Rao, Kalapala, Iwama, Kazuya, Davis, David A, Hasegawa, Kazuya, Murayama, Kazutaka, Yarchoan, Robert, Ghosh, Arun K, Pau, Alice K, Machida, Shinichi, Misumi, Shogo, Mitsuya, Hiroaki
Published in Science advances (14.07.2023)
Published in Science advances (14.07.2023)
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Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands
Ghosh, Arun K., Takayama, Jun, Kassekert, Luke A., Ella-Menye, Jean-Rene, Yashchuk, Sofiya, Agniswamy, Johnson, Wang, Yuan-Fang, Aoki, Manabu, Amano, Masayuki, Weber, Irene T., Mitsuya, Hiroaki
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
Published in Bioorganic & medicinal chemistry letters (01.11.2015)
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Journal Article
Front Cover: Design of Highly Potent, Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants (ChemMedChem 8/2018)
Ghosh, Arun K., Rao, Kalapala Venkateswara, Nyalapatla, Prasanth R., Kovela, Satish, Brindisi, Margherita, Osswald, Heather L., Sekhara Reddy, Bhavanam, Agniswamy, Johnson, Wang, Yuan‐Fang, Aoki, Manabu, Hattori, Shin‐ichiro, Weber, Irene T., Mitsuya, Hiroaki
Published in ChemMedChem (23.04.2018)
Published in ChemMedChem (23.04.2018)
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A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV
YEDIDI, Ravikiran S, GARIMELLA, Harisha, DAS, Debananda, WINGFIELD, Paul T, MAEDA, Kenji, GHOSH, Arun K, MITSUYA, Hiroaki, AOKI, Manabu, AOKI-OGATA, Hiromi, DESAI, Darshan V, CHANG, Simon B, DAVIS, David A, FYVIE, W. Sean, KAUFMAN, Joshua D, SMITH, David W
Published in Antimicrobial agents and chemotherapy (01.07.2014)
Published in Antimicrobial agents and chemotherapy (01.07.2014)
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