709 Trial in progress: product characteristics and clinical trial design for T-Plex, a multiplexed, enhanced T cell receptor-engineered T cell therapy for solid tumors
Chattopadhyay, Shrikanta, Boudot, Antoine J, Nayar, Ribhu, Bader, Hannah, Ferretti, Andrew, Traore, Tary, Nabilsi, Nancy, Tadros, Jenny, Kiaf, Badr, Wang, Yifan, Ospina, Victor, Mahopatra, Alok Das, Zhu, Zhonghua, Xu, Qikai, Daniels, Krista, Zimmerman, Briana, Jurewicz, Mollie, Kordosky, Amanda, Malcuit, Chris, Wang, Yun, Motta, Marlyane, Murray, Jim, Lockard, Ray, Gurer, Cagan, Barton, Debora, MacBeath, Gavin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
390 Discovery of MAGE-A1-specific TCR-T cell therapy candidates to expand multiplex therapy of solid tumors
Tadros, Jenny, Nabilsi, Nancy, Jurewicz, Mollie, Sharma, Akshat, Jahan, Kenneth L, Gaspar, Nicolas, Cirelli, Kimberly M, Parsons, Teagan, Khokhar, Shazad A, Kamalia, Shubhangi, Padmanabhan, Sveta, Kiaf, Badr, Nayar, Ribhu, Ospina, Victor, Mahopatra, Alok Das, Traore, Tary, Boudot, Antoine J, Dukaj, Livio, He, Jin, Kritzer, Ryan E, Cristofaro, Alexander, Pavuluri, Chandan K, Miga, Emily, Xu, Qikai, Wang, Yifan, Gurer, Cagan, MacBeath, Gavin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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376 Overcoming tumor heterogeneity – Clinical trial assays to prospectively assign patients customized multiplexed TCR-T cell therapy in Phase 1
Nayar, Ribhu, Khokhar, Shazad A, Jangalwe, Sonal, Padmanabhan, Sveta, Nabilsi, Nancy, Parsons, Teagan, Coleman, Jeffrey, Hsiung, Adam, Chang, Chunghun, Tsai, Henry, Arain, Shehla, Lozac’hmeur, Ariane, Nguyen, Andrew, Rathbun, Jessica, Yang, Qidi, Pham, Ruey, Harris, Sam, Soni, Shardul, Danek, Tyler, Marshall, Katie, Jensen, Amanda, Riley, Chris, Dukaj, Livio, Cristofaro, Alexander, Wang, Yun, Buonomo, Erica, Gurer, Cagan, Boudot, Antoine J, Chattopadhyay, Shrikanta, Barton, Debora, MacBeath, Gavin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
364 Non-clinical development of T-Plex component TSC-200-A0201: a natural HPV16 E7-specific TCR-T cell therapy for the treatment of HPV16-positive solid tumors
Jangalwe, Sonal, Kiaf, Badr, Pollacksmith, Daniel C, Kamalia, Shubhangi, Padmanabhan, Sveta, Bader, Hannah, Traore, Tary, Sharma, Nivya, Ospina, Victor, Goswamy, Debanjan, Mahopatra, Alok Das, Khokhar, Shazad A, Cirelli, Kimberly M, Karthik, Vivin, Jahan, Kenneth L, Gaspar, Nicolas, Dukaj, Livio, He, Jin, Kritzer, Ryan E, Cristofaro, Alexander, Pavuluri, Chandan K, Virbasius, Amy, Todorova, Elisaveta, Sinacola, Tyler M, Szemethy, Savannah G, Sur, Kyra N, Keskar, Vandana, Malcuit, Chris, Xu, Qikai, Wang, Yifan, Ramsdell, Danielle, Olivier, Kenneth, Boudot, Antoine J, Nayar, Ribhu, MacBeath, Gavin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Product Characteristics and Multi-Arm Clinical Trial Design for TSC-100 and TSC-101, TCR-T Cells That Target Leukemia Following Hematopoietic Cell Transplantation
Chattopadhyay, Shrikanta, Malcuit, Christopher, Takeuchi, Ryo, Hedblom, Emmett, Jaworowicz, Warren, Boudot, Antoine J, Bader, Hannah, Murray, James, Macbeath, Gavin
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Trial in Progress: A Phase 1 Umbrella Study of TCR-Engineered T Cells That Target HA-1 (TSC-100) and HA-2 (TSC-101) to Treat Residual Leukemia after Hematopoietic Cell Transplantation
Reshef, Ran, Suh, Hyung C., Al Malki, Monzr M., Matin, Aasiya, Kothari, Ashish S, Bell, Allison, Boudot, Antoine J, Wang, Yun, Abelowitz, Nina, Murray, James, Macbeath, Gavin, Barton, Debora, Chattopadhyay, Shrikanta
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Discovery of TSC-101: A First-in-Class Natural HA-2-Specific TCR to Treat Leukemia Following Hematopoietic Stem Cell Transplant Therapy
Nayar, Ribhu, Jurewicz, Mollie M, Jangalwe, Sonal, Bader, Hannah, Cirelli, Kimberly M, Basinski, Andrew, Pollacksmith, Daniel, Luther, Alexandra, Karaca, Cisem, Labrozzi, Anna, Daniel, Krista, Nip, Lisa, Ramsdell, Danielle, Virbasius, Amy, Perullo, Candace, Jahan, Kenneth L, Liao, Sida, Dukaj, Livio, Cristofaro, Alexandra, Chattopadhyay, Shrikanta, Olivier, Kenneth, Boudot, Antoine J, Xu, Qikai, Wang, Yifan, Gurer, Cagan, Macbeath, Gavin
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
NAYAR, Ribhu, MACBEATH, Gavin, JANGALWE, Sonal, POLLACKSMITH, Daniel, BOUDOT, Antoine, J
Year of Publication 18.09.2024
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Year of Publication 18.09.2024
Patent
BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, JANGALWE, Sonal, POLLACKSMITH, Daniel
Year of Publication 15.02.2024
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Year of Publication 15.02.2024
Patent
BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, JANGALWE, Sonal, POLLACKSMITH, Daniel
Year of Publication 18.01.2024
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Year of Publication 18.01.2024
Patent
BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
Jangalwe, Sonal, Boudot, Antoine J, MacBeath, Gavin, Pollacksmith, Daniel, Nayar, Ribhu
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
Patent
BINDING PROTEINS RECOGNIZING HA-2 ANTIGEN AND USES THEREOF
Jangalwe, Sonal, Basinski, Andrew S, Jurewicz, Mollie M, Boudot, Antoine J, MacBeath, Gavin, Xu, Qikai, Kula, Tomasz, Nayar, Ribhu
Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, JANGALWE, Sonal, POLLACKSMITH, Daniel
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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BINDING PROTEINS RECOGNIZING HPV16 E7 ANTIGEN AND USES THEREOF
JANGALWE, SONAL, NAYAR, RIBHU, POLLACKSMITH, DANIEL, MACBEATH, GAVIN, BOUDOT, ANTOINE J
Year of Publication 19.05.2023
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Year of Publication 19.05.2023
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BINDING PROTEINS RECOGNIZING HA-1 ANTIGEN AND USES THEREOF
Jangalwe, Sonal, Basinski, Andrew S, Jurewicz, Mollie M, Boudot, Antoine J, MacBeath, Gavin, Xu, Qikai, Kula, Tomasz, Nayar, Ribhu
Year of Publication 14.12.2023
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Year of Publication 14.12.2023
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BINDING PROTEINS RECOGNIZING HA-2 ANTIGEN AND USES THEREOF
NAYAR, Ribhu, BASINSKI, Andrew, S, MACBEATH, Gavin, JANGALWE, Sonal, JUREWICZ, Mollie, M, BOUDOT, Antoine, J, XU, Qikai, KULA, Tomasz
Year of Publication 21.02.2024
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Year of Publication 21.02.2024
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Binding proteins recognizing ha-2 antigen and uses thereof
NAYAR Ribhu, BOUDOT Antoine J, MACBEATH Gavin, JUREWICZ Mollie M, KULA Tomasz, BASINSKI Andrew S, JANGALWE Sonal, XU Qikai
Year of Publication 01.12.2023
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Year of Publication 01.12.2023
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BINDING PROTEINS RECOGNIZING HA-1 ANTIGEN AND USES THEREOF
NAYAR, Ribhu, BASINSKI, Andrew, S, MACBEATH, Gavin, JANGALWE, Sonal, JUREWICZ, Mollie, M, BOUDOT, Antoine, J, XU, Qikai, KULA, Tomasz
Year of Publication 13.09.2023
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Year of Publication 13.09.2023
Patent
Binding proteins recognizing HA-2 antigen and uses thereof
BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, BASINSKI, Andrew S, JUREWICZ, Mollie M, JANGALWE, Sonal, XU, Qikai, KULA, Tomasz
Year of Publication 10.08.2023
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Year of Publication 10.08.2023
Patent
Binding proteins recognizing HA-2 antigen and uses thereof
BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, BASINSKI, Andrew S, JUREWICZ, Mollie M, JANGALWE, Sonal, XU, Qikai, KULA, Tomasz
Year of Publication 13.04.2023
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Year of Publication 13.04.2023
Patent