Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599)
Mercier, Joël, Bani, Massimo, Colson, Anny-Odile, Germani, Massimiliano, Lalla, Marianna, Plisson, Christophe, Huiban, Mickael, Searle, Graham, Mathy, François-Xavier, Nicholl, Richard, Otoul, Christian, Smit, Johan Willem, van Asch, Vanja, Wagneur, Michel, Maguire, Ralph Paul
Published in Molecular imaging and biology (01.04.2024)
Published in Molecular imaging and biology (01.04.2024)
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Journal Article
A Virtual Screen for Diverse Ligands: Discovery of Selective G Protein-Coupled Receptor Antagonists
Engel, Stanislav, Skoumbourdis, Amanda P, Childress, John, Neumann, Susanne, Deschamps, Jeffrey R, Thomas, Craig J, Colson, Anny-Odile, Costanzi, Stefano, Gershengorn, Marvin C
Published in Journal of the American Chemical Society (16.04.2008)
Published in Journal of the American Chemical Society (16.04.2008)
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Journal Article
A Low Molecular Weight Agonist Signals by Binding to the Transmembrane Domain of Thyroid-stimulating Hormone Receptor (TSHR) and Luteinizing Hormone/Chorionic Gonadotropin Receptor (LHCGR)
Jäschke, Holger, Neumann, Susanne, Moore, Susanna, Thomas, Craig J., Colson, Anny-Odile, Costanzi, Stefano, Kleinau, Gunnar, Jiang, Jian-Kang, Paschke, Ralf, Raaka, Bruce M., Krause, Gerd, Gershengorn, Marvin C.
Published in The Journal of biological chemistry (14.04.2006)
Published in The Journal of biological chemistry (14.04.2006)
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Journal Article
Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2
Deflorian, Francesca, Engel, Stanislav, Colson, Anny-Odile, Raaka, Bruce M., Gershengorn, Marvin C., Costanzi, Stefano
Published in Proteins, structure, function, and bioinformatics (01.05.2008)
Published in Proteins, structure, function, and bioinformatics (01.05.2008)
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Journal Article
Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program
Brodie, Martin J., Fakhoury, Toufic, McDonough, Belinda, Colson, Anny-Odile, Stockis, Armel, Elmoufti, Sami, Whitesides, John
Published in Epilepsy research (01.09.2018)
Published in Epilepsy research (01.09.2018)
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Journal Article
Efficacy, safety and tolerability of rozanolixizumab in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a randomised, subject-blind, investigator-blind, placebo-controlled, phase 2a trial and open-label extension study
Querol, Luis, De Sèze, Jérôme, Dysgaard, Tina, Levine, Todd, Rao, T Hemanth, Rivner, Michael, Hartung, Hans-Peter, Kiessling, Peter, Shimizu, Saori, Marmol, Dominika, Bozorg, Ali, Colson, Anny-Odile, Massow, Ute, Eftimov, Filip, Bleecker, Jan De, Claeys, Kristl G, Debien, Elisa, Noordhout, Alain Maertens de, Sommer, Claudia, Garz, Katharina, Stettner, Mark, Schmidt, Jens, Fernández, Nuria Vidal, Gámez, Josep, Segura, Anna Canovas, Morales, Raúl Juntas, Hewamadduma, Channa, Haslam, Liam, Quarles, Brandy, Gable, Karissa
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2024)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2024)
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Journal Article
Ketopiperazines: Conformationally Constrained Peptidomimetic of Arginine Amides
Chen, Zecheng, Kende, Andrew S., Colson, Anny-Odile, Mendezandino, Jose L., Ebetino, Frank H., Bush, Rod D., Hu, X. Eric
Published in Synthetic communications (01.03.2006)
Published in Synthetic communications (01.03.2006)
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Journal Article
A Hydrophobic Cluster between Transmembrane Helices 5 and 6 Constrains the Thyrotropin-Releasing Hormone Receptor in an Inactive Conformation
Colson, A O, Perlman, J H, Jinsi-Parimoo, A, Nussenzveig, D R, Osman, R, Gershengorn, M C
Published in Molecular pharmacology (01.12.1998)
Published in Molecular pharmacology (01.12.1998)
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Journal Article
P2Y1 Antagonists: Combining Receptor-Based Modeling and QSAR for a Quantitative Prediction of the Biological Activity Based on Consensus Scoring
Costanzi, Stefano, Tikhonova, Irina G, Ohno, Michihiro, Roh, Eun Joo, Joshi, Bhalchandra V, Colson, Anny-Odile, Houston, Dayle, Maddileti, Savitri, Harden, T. Kendall, Jacobson, Kenneth A
Published in Journal of medicinal chemistry (12.07.2007)
Published in Journal of medicinal chemistry (12.07.2007)
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Journal Article
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Klopfenstein, Sean R., Evdokimov, Artem G., Colson, Anny-Odile, Fairweather, Neil T., Neuman, Jeffrey J., Maier, Matthew B., Gray, Jeffrey L., Gerwe, Gina S., Stake, George E., Howard, Brian W., Farmer, Julie A., Pokross, Matthew E., Downs, Thomas R., Kasibhatla, Bhavani, Peters, Kevin G.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
Discovery of Orally Bioavailable 1,3,4-Trisubstituted 2-Oxopiperazine-Based Melanocortin-4 Receptor Agonists as Potential Antiobesity Agents
Tian, Xinrong, Switzer, Adrian G, Derose, Steve A, Mishra, Rajesh K, Solinsky, Mark G, Mumin, Rashid N, Ebetino, Frank H, Jayasinghe, Lalith R, Webster, Mark E, Colson, Anny-Odile, Crossdoersen, Doreen, Pinney, Beth B, Farmer, Julie A, Dowty, Martin E, Obringer, Cindy M, Cruze, Charles A, Burklow, Melissa L, Suchanek, Paula M, Dong, Lily, Dirr, Mary Kay, Sheldon, Russell J, Wos, John A
Published in Journal of medicinal chemistry (09.10.2008)
Published in Journal of medicinal chemistry (09.10.2008)
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Journal Article
Design and synthesis of potent, non-peptidic inhibitors of HPTPβ
Amarasinghe, Kande K.D., Evidokimov, Artem G., Xu, Kevin, Clark, Cynthia M., Maier, Matthew B., Srivastava, Anil, Colson, Anny-Odile, Gerwe, Gina S., Stake, George E., Howard, Brian W., Pokross, Matthew E., Gray, Jeffrey L., Peters, Kevin G.
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
Published in Bioorganic & medicinal chemistry letters (15.08.2006)
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Journal Article
Corrigendum to “Design and synthesis of potent, non-peptidic inhibitors of HPTPβ” [Bioorg. Med. Chem. Lett. 16 (2006) 4252–4256]
Amarasinghe, Kande K.D., Evdokimov, Artem G., Xu, Kevin, Clark, Cynthia M., Maier, Matthew B., Srivastava, Anil, Colson, Anny-Odile, Gerwe, Gina S., Stake, George E., Howard, Brian W., Pokross, Matthew E., Gray, Jeffrey L., Peters, Kevin G.
Published in Bioorganic & medicinal chemistry letters (15.08.2008)
Published in Bioorganic & medicinal chemistry letters (15.08.2008)
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Journal Article
Solid-Supported Synthesis of a Peptide β-Turn Mimetic
Golebiowski, Adam, Klopfenstein, Sean R, Shao, Xia, Chen, Jack J, Colson, Anny-Odile, Grieb, Arthur L, Russell, Anne F
Published in Organic letters (24.08.2000)
Published in Organic letters (24.08.2000)
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Journal Article
Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists
Meyers, Kenneth M., Méndez-Andino, José, Colson, Anny-Odile, Hu, X. Eric, Wos, John A., Mitchell, Maria C., Hodge, Karen, Howard, Jeremy, Paris, Jennifer L., Dowty, Martin E., Obringer, Cindy M., Reizes, Ofer
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Journal Article
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: A novel class of potent MCH-R1 antagonists
Méndez-Andino, José L., Colson, Anny-Odile, Meyers, Kenneth M., Mitchell, Maria C., Hodge, Karen, Howard, Jeremy M., Kim, Nicholas, Ackley, David C., Holbert, Jerry K., Mittelstadt, Scott W., Dowty, Martin E., Obringer, Cindy M., Suchanek, Paula, Reizes, Ofer, Eric Hu, X., Wos, John A.
Published in Bioorganic & medicinal chemistry (01.03.2007)
Published in Bioorganic & medicinal chemistry (01.03.2007)
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