Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies
Yeung, Kap-Sun, Beno, Brett R, Parcella, Kyle, Bender, John A, Grant-Young, Katherine A, Nickel, Andrew, Gunaga, Prashantha, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Rigat, Karen, Wang, Ying-Kai, Liu, Mengping, Lemm, Julie, Mosure, Kathy, Sheriff, Steven, Wan, Changhong, Witmer, Mark, Kish, Kevin, Hanumegowda, Umesh, Zhuo, Xiaoliang, Shu, Yue-Zhong, Parker, Dawn, Haskell, Roy, Ng, Alicia, Gao, Qi, Colston, Elizabeth, Raybon, Joseph, Grasela, Dennis M, Santone, Kenneth, Gao, Min, Meanwell, Nicholas A, Sinz, Michael, Soars, Matthew G, Knipe, Jay O, Roberts, Susan B, Kadow, John F
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Journal Article
Synthesis and characterization of a series of N,N′‐substituted urea derivatives by using electrospray ionization tandem mass spectrometry: Differentiation of positional isomers
Singh, Dilip Kumar, Chauthe, Siddheshwar Kisan, Anjanappa, Prakash, Kumar, Sumit, Arulraj, Ruba A., Gajjela, Raju, Mohammed, Noor, Kanthappa, Venkatesh T., Karmakar, Ananta, Gupta, Arun Kumar, Bajpai, Lakshmikant, Bagadi, Muralidhararao, Mathur, Arvind
Published in Rapid communications in mass spectrometry (15.10.2021)
Published in Rapid communications in mass spectrometry (15.10.2021)
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Journal Article
BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate
Cherney, Robert J, Anjanappa, Prakash, Selvakumar, Kumaravel, Batt, Douglas G, Brown, Gregory D, Rose, Anne V, Vuppugalla, Ragini, Chen, Jing, Pang, Jian, Xu, Songmei, Yarde, Melissa, Tebben, Andrew J, Paidi, Venkatram Reddy, Cvijic, Mary Ellen, Mathur, Arvind, Barrish, Joel C, Mandlekar, Sandhya, Zhao, Qihong, Carter, Percy H
Published in ACS medicinal chemistry letters (11.11.2021)
Published in ACS medicinal chemistry letters (11.11.2021)
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Journal Article
Practical Synthesis of (3aR, 9bR)‑8-Fluoro-7-(perfluoropropan-2-yl)-9b-(phenylsulfonyl)-2,3,3a,4,5,9b-hexahydro‑1H‑benzo[e]indole: An Advanced Intermediate to Access the RORγt Inverse Agonist BMT-362265
Karmakar, Ananta, Nimje, Roshan Y, Silamkoti, Arundutt, Pitchai, Manivel, Basha, Mushkin, Singarayer, Christuraj, Ramasamy, Duraisamy, Babu, G. T. Venkatesh, Samikannu, Ramesh, Subramaniam, Srinath, Anjanappa, Prakash, Vetrichelvan, Muthalagu, Kumar, Hemantha, Dikundwar, Amol G, Gupta, Anuradha, Gupta, Arun Kumar, Rampulla, Richard, Dhar, T. G. Murali, Mathur, Arvind
Published in Organic process research & development (16.04.2021)
Published in Organic process research & development (16.04.2021)
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Journal Article
Practical Synthesis of (3a R , 9b R )-8-Fluoro-7-(perfluoropropan-2-yl)-9b-(phenylsulfonyl)-2,3,3a,4,5,9b-hexahydro-1 H -benzo[e]indole: An Advanced Intermediate to Access the RORγt Inverse Agonist BMT-362265
Karmakar, Ananta, Nimje, Roshan Y., Silamkoti, Arundutt, Pitchai, Manivel, Basha, Mushkin, Singarayer, Christuraj, Ramasamy, Duraisamy, Babu, G. T. Venkatesh, Samikannu, Ramesh, Subramaniam, Srinath, Anjanappa, Prakash, Vetrichelvan, Muthalagu, Kumar, Hemantha, Dikundwar, Amol G., Gupta, Anuradha, Gupta, Arun Kumar, Rampulla, Richard, Dhar, T. G. Murali, Mathur, Arvind
Published in Organic process research & development (16.04.2021)
Published in Organic process research & development (16.04.2021)
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Journal Article
Discovery and Optimization of Aryl Piperidinone Ureas as Selective Formyl Peptide Receptor 2 Agonists
Wurtz, Nicholas R., Shirude, Pravin S., Cheney, Daniel L., Lupisella, John A., Chattopadhyay, Amit Kumar, Baligar, Vishweshwaraiah, Seshadri, Balaji, Anjanappa, Prakash, Viet, Andrew, Valente, Meriah N., Hsu, Mei-Yin, Abousleiman, Mojgan, Sarodaya, Sanket, Tagore, Debarati M., Dudhgaonkar, Shailesh, Putlur, Sivaprasad, Dierks, Elizabeth A., Ostrowski, Jacek, Wexler, Ruth R., Garcia, Ricardo, Kick, Ellen K.
Published in ACS medicinal chemistry letters (12.09.2024)
Published in ACS medicinal chemistry letters (12.09.2024)
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Journal Article
Development of a Scalable Synthesis for the Potent Kinase Inhibitor BMS-986236 ; 1-(5-(4-(3-Hydroxy-3-methylbutyl)-1 H -1,2,3-triazol-1-yl)-4-(isopropylamino)pyridin-2-yl)-1 H -pyrazolo[3,4- b ]pyridine-5-carbonitrile
Arunachalam, Pirama Nayagam, Kuppusamy, Prakasam, Ganesan, Sivakumar, Krishnamoorthy, Suresh, Nimje, Roshan Y., Jarugu, Lokesh Babu, Kanikahalli Chikkananjaiah, Nanjundaswamy, Anki Reddy, China, Anjanappa, Prakash, Botlagunta, Murali, Vanteru, Sridhar, Maddala, Nageswararao, Shankar, Muniyappa, Nair, Satheesh, Hynes, John, Santella, Joseph B., Carter, Percy H., Rampulla, Richard, Vetrichelvan, Muthalagu, Gupta, Anuradha, Gupta, Arun Kumar, Mathur, Arvind
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
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Journal Article
Development of a Scalable Synthesis for the Potent Kinase Inhibitor BMS-986236; 1‑(5-(4-(3-Hydroxy-3-methylbutyl)‑1H‑1,2,3-triazol-1-yl)-4-(isopropylamino)pyridin-2-yl)‑1H‑pyrazolo[3,4‑b]pyridine-5-carbonitrile
Arunachalam, Pirama Nayagam, Kuppusamy, Prakasam, Ganesan, Sivakumar, Krishnamoorthy, Suresh, Nimje, Roshan Y, Jarugu, Lokesh Babu, Kanikahalli Chikkananjaiah, Nanjundaswamy, Anki Reddy, China, Anjanappa, Prakash, Botlagunta, Murali, Vanteru, Sridhar, Maddala, Nageswararao, Shankar, Muniyappa, Nair, Satheesh, Hynes, John, Santella, Joseph B, Carter, Percy H, Rampulla, Richard, Vetrichelvan, Muthalagu, Gupta, Anuradha, Gupta, Arun Kumar, Mathur, Arvind
Published in Organic process research & development (17.05.2019)
Published in Organic process research & development (17.05.2019)
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Journal Article
Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors
Yeung, Kap-Sun, Beno, Brett R, Mosure, Kathy, Zhu, Juliang, Grant-Young, Katherine A, Parcella, Kyle, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Wang, Ying-Kai, Fang, Hua, Krause, Rudolph, Rigat, Karen, Liu, Mengping, Lemm, Julie, Sheriff, Steven, Witmer, Mark, Tredup, Jeffrey, Jardel, Adam, Kish, Kevin, Parker, Dawn, Haskell, Roy, Santone, Kenneth, Meanwell, Nicholas A, Soars, Matthew G, Roberts, Susan B, Kadow, John F
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
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Journal Article
BENZOFURAN DERIVATIVES FOR THE TREATMENT OF HEPATITIS C
Selvakumar, Kumaravel, Kadow, John F, Gupta, Samayamunthula Venkata Satya Arun, Yeung, Kap-Sun, Bora, Rajesh Onkardas, Anjanappa, Prakash
Year of Publication 17.09.2020
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Year of Publication 17.09.2020
Patent
Compounds for the treatment of hepatitis C
Gupta, Samayamunthula Venkata Satya Arun Kumar, Kadow, John F, Yeung, Kap-Sun, Bora, Rajesh Onkardas, Anjanappa, Prakash
Year of Publication 11.12.2018
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Year of Publication 11.12.2018
Patent
ChemInform Abstract: Carbamic Acid 2-Trimethylsilylethyl Ester as a New Ammonia Equivalent for Palladium-Catalyzed Amination of Aryl Halides
Mullick, Dibakar, Anjanappa, Prakash, Selvakumar, Kumaravel, Ruckmani, Kandasamy, Sivakumar, Manickam
Published in ChemInform (01.03.2011)
Published in ChemInform (01.03.2011)
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Journal Article
NOVEL COMPOUNDS FOR THE TREATMENT OF HEPATITIS C
ANJANAPPA, Prakash, BORA, Rajesh Onkardas, YEUNG, Kap-Sun, KADOW, John F, GUPTA, Samayamunthula Venkata Satya Arun Kumar
Year of Publication 03.01.2018
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Year of Publication 03.01.2018
Patent