Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity
Lucas-Hourani, Marianne, Dauzonne, Daniel, Jorda, Pierre, Cousin, Gaëlle, Lupan, Alexandru, Helynck, Olivier, Caignard, Grégory, Janvier, Geneviève, André-Leroux, Gwénaëlle, Khiar, Samira, Escriou, Nicolas, Desprès, Philippe, Jacob, Yves, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidalain, Pierre-Olivier
Published in PLoS pathogens (01.10.2013)
Published in PLoS pathogens (01.10.2013)
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Journal Article
Expanding the Substrate Scope of Native Amine Dehydrogenases through In Silico Structural Exploration and Targeted Protein Engineering
Ducrot, Laurine, Bennett, Megan, André‐Leroux, Gwenaëlle, Elisée, Eddy, Marynberg, Sacha, Fossey‐Jouenne, Aurélie, Zaparucha, Anne, Grogan, Gideon, Vergne‐Vaxelaire, Carine
Published in ChemCatChem (22.11.2022)
Published in ChemCatChem (22.11.2022)
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Journal Article
Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling
Wagner, Tristan, André-Leroux, Gwénaëlle, Hindie, Valérie, Barilone, Nathalie, Lisa, María-Natalia, Hoos, Sylviane, Raynal, Bertrand, Vulliez-Le Normand, Brigitte, O'Hare, Helen M, Bellinzoni, Marco, Alzari, Pedro M
Published in Science signaling (07.05.2019)
Published in Science signaling (07.05.2019)
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Journal Article
Identification of Novel Compounds Inhibiting the Kinase Activity of the CDK5/p25 Complex via Direct Binding to p25
Jabeur, Riheb, Corbel, Caroline, Loyer, Pascal, Le Parc, Annabelle, Le Grand, Adélaide, Comte, Arnaud, Bach, Stéphane, André-Leroux, Gwenaëlle, Sire, Olivier, Ben Mansour, Hedi, Le Tilly, Véronique
Published in Biochemistry (Easton) (02.05.2023)
Published in Biochemistry (Easton) (02.05.2023)
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Journal Article
Altered spinogenesis in iPSC-derived cortical neurons from patients with autism carrying de novo SHANK3 mutations
Gouder, Laura, Vitrac, Aline, Goubran-Botros, Hany, Danckaert, Anne, Tinevez, Jean-Yves, André-Leroux, Gwenaëlle, Atanasova, Ekaterina, Lemière, Nathalie, Biton, Anne, Leblond, Claire S., Poulet, Aurélie, Boland, Anne, Deleuze, Jean-François, Benchoua, Alexandra, Delorme, Richard, Bourgeron, Thomas, Cloëz-Tayarani, Isabelle
Published in Scientific reports (14.01.2019)
Published in Scientific reports (14.01.2019)
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Journal Article
The pro-inflammatory cytokine 14-3-3ε is a ligand of CD13 in cartilage
Nefla, Meriam, Sudre, Laure, Denat, Guillaume, Priam, Sabrina, Andre-Leroux, Gwenaëlle, Berenbaum, Francis, Jacques, Claire
Published in Journal of cell science (01.09.2015)
Published in Journal of cell science (01.09.2015)
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Journal Article
The signaling peptide PapR is required for the activity of the quorum-sensor PlcRa in Bacillus thuringiensis
Huillet, Eugénie, Bridoux, Ludovic, Barboza, Isabelle, Lemy, Christelle, André-Leroux, Gwenaëlle, Lereclus, Didier
Published in Microbiology (Society for General Microbiology) (01.04.2020)
Published in Microbiology (Society for General Microbiology) (01.04.2020)
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Journal Article
CNTN6 mutations are risk factors for abnormal auditory sensory perception in autism spectrum disorders
Mercati, O, Huguet, G, Danckaert, A, André-Leroux, G, Maruani, A, Bellinzoni, M, Rolland, T, Gouder, L, Mathieu, A, Buratti, J, Amsellem, F, Benabou, M, Van-Gils, J, Beggiato, A, Konyukh, M, Bourgeois, J-P, Gazzellone, M J, Yuen, R K C, Walker, S, Delépine, M, Boland, A, Régnault, B, Francois, M, Van Den Abbeele, T, Mosca-Boidron, A L, Faivre, L, Shimoda, Y, Watanabe, K, Bonneau, D, Rastam, M, Leboyer, M, Scherer, S W, Gillberg, C, Delorme, R, Cloëz-Tayarani, I, Bourgeron, T
Published in Molecular psychiatry (01.04.2017)
Published in Molecular psychiatry (01.04.2017)
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Journal Article
Heme Uptake in Lactobacillus sakei Evidenced by a New Energy Coupling Factor (ECF)-Like Transport System
Verplaetse, Emilie, André-Leroux, Gwenaëlle, Duhutrel, Philippe, Coeuret, Gwendoline, Chaillou, Stéphane, Nielsen-Leroux, Christina, Champomier-Vergès, Marie-Christine
Published in Applied and environmental microbiology (01.09.2020)
Published in Applied and environmental microbiology (01.09.2020)
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Journal Article
Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis
Lisa, María-Natalia, Gil, Magdalena, André-Leroux, Gwénaëlle, Barilone, Nathalie, Durán, Rosario, Biondi, Ricardo M., Alzari, Pedro M.
Published in Structure (London) (02.06.2015)
Published in Structure (London) (02.06.2015)
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Journal Article
Structural Modeling of Cell Wall Peptidase CwpFM (EntFM) Reveals Distinct Intrinsically Disordered Extensions Specific to Pathogenic Bacillus cereus Strains
Tran, Seav-Ly, Cormontagne, Delphine, Vidic, Jasmina, André-Leroux, Gwenaëlle, Ramarao, Nalini
Published in Toxins (14.09.2020)
Published in Toxins (14.09.2020)
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Journal Article
Intraspecific Diversity of Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii
Auger, Sandrine, Kropp, Camille, Borras-Nogues, Esther, Chanput, Wasaporn, Andre-Leroux, Gwenaelle, Gitton-Quent, Oscar, Benevides, Leandro, Breyner, Natalia, Azevedo, Vasco, Langella, Philippe, Chatel, Jean-Marc
Published in International journal of molecular sciences (01.02.2022)
Published in International journal of molecular sciences (01.02.2022)
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Journal Article
Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential
Wehenkel, Annemarie, Bellinzoni, Marco, Graña, Martin, Duran, Rosario, Villarino, Andrea, Fernandez, Pablo, Andre-Leroux, Gwénaëlle, England, Patrick, Takiff, Howard, Cerveñansky, Carlos, Cole, Stewart T., Alzari, Pedro M.
Published in Biochimica et biophysica acta (2008)
Published in Biochimica et biophysica acta (2008)
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Journal Article
Identification of Hanks-Type Kinase PknB-Specific Targets in the Streptococcus thermophilus Phosphoproteome
Henry, Céline, Haller, Lucia, Blein-Nicolas, Mélisande, Zivy, Michel, Canette, Alexis, Verbrugghe, Morgane, Mézange, Christine, Boulay, Mylène, Gardan, Rozenn, Samson, Samantha, Martin, Véronique, André-Leroux, Gwenaëlle, Monnet, Véronique
Published in Frontiers in microbiology (19.06.2019)
Published in Frontiers in microbiology (19.06.2019)
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Journal Article
Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor
Lisa, María-Natalia, Cvirkaite-Krupovic, Virginija, Richet, Evelyne, André-Leroux, Gwenaëlle, Alzari, Pedro M, Haouz, Ahmed, Danot, Olivier
Published in Nucleic acids research (23.04.2019)
Published in Nucleic acids research (23.04.2019)
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Journal Article
Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis
Le, Nguyen-Hung, Molle, Virginie, Eynard, Nathalie, Miras, Mathieu, Stella, Alexandre, Bardou, Fabienne, Galandrin, Ségolène, Guillet, Valérie, André-Leroux, Gwenaëlle, Bellinzoni, Marco, Alzari, Pedro, Mourey, Lionel, Burlet-Schiltz, Odile, Daffé, Mamadou, Marrakchi, Hedia
Published in The Journal of biological chemistry (21.10.2016)
Published in The Journal of biological chemistry (21.10.2016)
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Journal Article
The FHA-containing protein GarA acts as a phosphorylation-dependent molecular switch in mycobacterial signaling
England, Patrick, Wehenkel, Annemarie, Martins, Sonia, Hoos, Sylviane, André-Leroux, Gwénaëlle, Villarino, Andrea, Alzari, Pedro M.
Published in FEBS letters (22.01.2009)
Published in FEBS letters (22.01.2009)
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Journal Article
OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity
Segovia, Danilo, Haouz, Ahmed, Porley, Darío, Olivero, Natalia, Martínez, Mariano, Mariadassou, Mahendra, Berois, Mabel, André-Leroux, Gwenaëlle, Villarino, Andrea
Published in Journal of molecular biology (01.09.2017)
Published in Journal of molecular biology (01.09.2017)
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Journal Article
14-3-3E, a new alarmin candidate, elicits a catabolic and proinflammatory effect involving innate immunity through TLR signaling in osteoarthritis
Millerand, M., Sudre, L., Nefla, M., Pene, F., Rousseau, C., Ravat, A., Pons, A., Andre-Leroux, G., Berenbaum, F., Jacques, C.
Published in Osteoarthritis and cartilage (01.04.2019)
Published in Osteoarthritis and cartilage (01.04.2019)
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Journal Article