Time course of skeletal muscle loss and oxidative stress in rats with walker 256 solid tumor
Guarnier, Flávia A., Cecchini, Alessandra L., Suzukawa, Andréia A., Maragno, Ana Leticia G.C., Simão, Andréa N.C., Gomes, Marcelo D., Cecchini, Rubens
Published in Muscle & nerve (01.12.2010)
Published in Muscle & nerve (01.12.2010)
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Testosterone represses ubiquitin ligases atrogin-1 and Murf-1 expression in an androgen-sensitive rat skeletal muscle in vivo
Pires-Oliveira, Marcelo, Maragno, Ana Leticia G. C, Parreiras-e-Silva, Lucas T, Chiavegatti, Tiago, Gomes, Marcelo D, Godinho, Rosely O
Published in Journal of applied physiology (1985) (01.02.2010)
Published in Journal of applied physiology (1985) (01.02.2010)
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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
Kotschy, András, Szlavik, Zoltán, Murray, James, Davidson, James, Maragno, Ana Leticia, Le Toumelin-Braizat, Gaëtane, Chanrion, Maïa, Kelly, Gemma L., Gong, Jia-Nan, Moujalled, Donia M., Bruno, Alain, Csekei, Márton, Paczal, Attila, Szabo, Zoltán B., Sipos, Szabolcs, Radics, Gábor, Proszenyak, Agnes, Balint, Balázs, Ondi, Levente, Blasko, Gábor, Robertson, Alan, Surgenor, Allan, Dokurno, Pawel, Chen, Ijen, Matassova, Natalia, Smith, Julia, Pedder, Christopher, Graham, Christopher, Studeny, Aurélie, Lysiak-Auvity, Gaëlle, Girard, Anne-Marie, Gravé, Fabienne, Segal, David, Riffkin, Chris D., Pomilio, Giovanna, Galbraith, Laura C. A., Aubrey, Brandon J., Brennan, Margs S., Herold, Marco J., Chang, Catherine, Guasconi, Ghislaine, Cauquil, Nicolas, Melchiore, Fabien, Guigal-Stephan, Nolwen, Lockhart, Brian, Colland, Frédéric, Hickman, John A., Roberts, Andrew W., Huang, David C. S., Wei, Andrew H., Strasser, Andreas, Lessene, Guillaume, Geneste, Olivier
Published in Nature (London) (27.10.2016)
Published in Nature (London) (27.10.2016)
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Identification of FBXO25-interacting proteins using an integrated proteomics approach
Teixeira, Felipe R, Yokoo, Sami, Gartner, Carlos A, Manfiolli, Adriana O, Baqui, Munira M.A, Assmann, Eliana M, Maragno, Ana Leticia G.C, Yu, Huijun, de Lanerolle, Primal, Kobarg, Jörg, Gygi, Steven P, Gomes, Marcelo Damário
Published in Proteomics (Weinheim) (01.08.2010)
Published in Proteomics (Weinheim) (01.08.2010)
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Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia
Moujalled, Donia M., Pomilio, Giovanna, Ghiurau, Corina, Ivey, Adam, Salmon, Jessica, Rijal, Sewa, Macraild, Sarah, Zhang, Lan, Teh, Tse-Chieh, Tiong, Ing-Soo, Lan, Ping, Chanrion, Maia, Claperon, Audrey, Rocchetti, Francesca, Zichi, Adrien, Kraus-Berthier, Laurence, Wang, Youzhen, Halilovic, Ensar, Morris, Erick, Colland, Frédéric, Segal, David, Huang, David, Roberts, Andrew W., Maragno, Ana Leticia, Lessene, Guillaume, Geneste, Olivier, Wei, Andrew H.
Published in Leukemia (01.04.2019)
Published in Leukemia (01.04.2019)
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Journal Article
Discovery of S64315, a Potent and Selective Mcl‑1 Inhibitor
Szlavik, Zoltan, Csekei, Marton, Paczal, Attila, Szabo, Zoltan B, Sipos, Szabolcs, Radics, Gabor, Proszenyak, Agnes, Balint, Balazs, Murray, James, Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E, Daniels, Zoe Marie, Hubbard, Roderick E, Le Toumelin-Braizat, Gaëtane, Claperon, Audrey, Lysiak-Auvity, Gaëlle, Girard, Anne-Marie, Bruno, Alain, Chanrion, Maia, Colland, Frédéric, Maragno, Ana-Leticia, Demarles, Didier, Geneste, Olivier, Kotschy, Andras
Published in Journal of medicinal chemistry (25.11.2020)
Published in Journal of medicinal chemistry (25.11.2020)
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FBXO25, an F-box protein homologue of atrogin-1, is not induced in atrophying muscle
Maragno, Ana Leticia G.C., Baqui, Munira M.A., Gomes, Marcelo D.
Published in Biochimica et biophysica acta (01.06.2006)
Published in Biochimica et biophysica acta (01.06.2006)
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Cotargeting BCL-2 and MCL-1 in high-risk B-ALL
Moujalled, Donia M., Hanna, Diane T., Hediyeh-zadeh, Soroor, Pomilio, Giovanna, Brown, Lauren, Litalien, Veronique, Bartolo, Ray, Fleming, Shaun, Chanrion, Maïa, Banquet, Sébastien, Maragno, Ana-Leticia, Kraus-Berthier, Laurence, Schoumacher, Marie, Mullighan, Charles G., Georgiou, Angela, White, Christine A., Lessene, Guillaume, Huang, David C.S., Roberts, Andrew W., Geneste, Olivier, Rasmussen, Lorna, Davis, Melissa J., Ekert, Paul G., Wei, Andrew, Ng, Ashley P., Khaw, Seong L.
Published in Blood advances (23.06.2020)
Published in Blood advances (23.06.2020)
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The Effect of Core Replacement on S64315, a Selective MCL‑1 Inhibitor, and Its Analogues
Sipos, Szabolcs, Bálint, Balázs, Szabó, Zoltán B, Ondi, Levente, Csékei, Márton, Szlávik, Zoltán, Proszenyák, Ágnes, Murray, James B, Davidson, James, Chen, Ijen, Dokurno, Pawel, Surgenor, Allan E, Pedder, Christopher, Hubbard, Roderick E, Maragno, Ana-Leticia, Chanrion, Maia, Colland, Frederic, Geneste, Olivier, Kotschy, András
Published in ACS omega (31.08.2021)
Published in ACS omega (31.08.2021)
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ISG15 modulates development of the erythroid lineage
Maragno, Ana Leticia, Pironin, Martine, Alcalde, Hélène, Cong, Xiuli, Knobeloch, Klaus-Peter, Tangy, Frederic, Zhang, Dong-Er, Ghysdael, Jacques, Quang, Christine Tran
Published in PloS one (12.10.2011)
Published in PloS one (12.10.2011)
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Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer
Merino, Delphine, Whittle, James R, Vaillant, François, Serrano, Antonin, Gong, Jia-Nan, Giner, Goknur, Maragno, Ana Leticia, Chanrion, Maïa, Schneider, Emilie, Pal, Bhupinder, Li, Xiang, Dewson, Grant, Gräsel, Julius, Liu, Kevin, Lalaoui, Najoua, Segal, David, Herold, Marco J, Huang, David C S, Smyth, Gordon K, Geneste, Olivier, Lessene, Guillaume, Visvader, Jane E, Lindeman, Geoffrey J
Published in Science translational medicine (02.08.2017)
Published in Science translational medicine (02.08.2017)
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Journal Article
Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Moujalled, Donia M, Brown, Fiona C, Pomilio, Giovanna, Anstee, Natasha S, Litalien, Veronique, Thompson, Ella R, Morley, Thomas, MacRaild, Sarah, Chua, Chong C, Banquet, SéBastien, Chanrion, Maia, Maragno, Ana-Leticia, Schoumacher, Marie, Herold, Marco J, Lessene, Guillaume, Geneste, Olivier, Huang, David C.S., Roberts, Andrew W, Blombery, Piers, Wei, Andrew
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia
Moujalled, Donia M, Hanna, Diane T, Pomilio, Giovanna, Litalien, Veronique, Fleming, Shaun, Chanrion, Marie, Maragno, Ana-Leticia, Kraus-Berthier, Laurence, Khaw, Seong Lin, Lessene, Guillaume, Huang, David, Roberts, Andrew W., Geneste, Olivier, Ekert, Paul G, Ng, Ashley P, Wei, Andrew H
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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IDENTIFICATION OF POTENT BH3-MIMETIC COMBINATIONS TARGETING PRO-SURVIVAL PATHWAYS IN HUMAN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Moujalled, Donia, Hanna, Diane, Pomillio, Giovanna, Litalien, Veronique, Fleming, Shaun, Chanrion, Marie, Maragno, Ana-Leticia, Kraus-Berthier, Laurence, Khaw, Seong, Lessene, Guillaume, Huang, David, Roberts, Andrew, Geneste, Olivier, Ekert, Paul, Ng, Ashley, Wei, Andrew
Published in Experimental hematology (01.08.2019)
Published in Experimental hematology (01.08.2019)
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Journal Article
Abstract 4482: S64315 (MIK665) is a potent and selective Mcl1 inhibitor with strong antitumor activity across a diverse range of hematologic tumor models
Maragno, Ana Leticia, Mistry, Prakash, Kotschy, András, Szlavik, Zoltán, Murray, James, Davidson, James, Toumelin-Braizat, Gaëtane Le, Chanrion, Maïa, Bruno, Alain, Claperon, Audrey, Maacke, Heiko, Morris, Erick, Wang, Youzhen, Derreal, Alix, Csekei, Márton, Paczal, Attila, Szabo, Zoltán, Sipos, Szabolcs, Proszenyak, Agnes, Balint, Balázs, Surgenor, Allan, Dokurno, Pawel, Matassova, Natalia, Chen, Ijen, Lysiak-Auvity, Gaëlle, Girard, Anne-Marie, Grave, Fabienne, Colland, Frédéric, Halilovic, Ensar, Geneste, Olivier
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 4477: MIK665/S64315, a novel Mcl-1 inhibitor, in combination with Bcl-2 inhibitors exhibits strong synergistic antitumor activity in a range of hematologic malignancies
Halilovic, Ensar, Chanrion, Maïa, Mistry, Prakash, Wartmann, Markus, Qiu, Shumei, Sanghavi, Sneha, Chen, Yan, Lysiak, Gaëlle, Maragno, Ana Leticia, Pfaar, Ulrike, Huth, Felix, Schoumacher, Marie, Claperon, Audrey, Kraus-Berthier, Laurence, Banquet, Sébastien, Derreal, Alix, Maacke, Heiko, Colland, Frédéric, Geneste, Olivier, Morris, Erick, Wang, Youzhen
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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