Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission
Roy, Chandra N, Shu, Sherry T, Kline, Christopher, Rigatti, Lora, Smithgall, Thomas E, Ambrose, Zandrea
Published in Scientific reports (10.10.2023)
Published in Scientific reports (10.10.2023)
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A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing
Siddiqui, Mohammad Adnan, Saito, Akatsuki, Halambage, Upul D, Ferhadian, Damien, Fischer, Douglas K, Francis, Ashwanth C, Melikyan, Gregory B, Ambrose, Zandrea, Aiken, Christopher, Yamashita, Masahiro
Published in Journal of virology (15.08.2019)
Published in Journal of virology (15.08.2019)
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Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis
Xu, Chaoyi, Fischer, Douglas K, Rankovic, Sanela, Li, Wen, Dick, Robert A, Runge, Brent, Zadorozhnyi, Roman, Ahn, Jinwoo, Aiken, Christopher, Polenova, Tatyana, Engelman, Alan N, Ambrose, Zandrea, Rousso, Itay, Perilla, Juan R
Published in PLoS biology (17.12.2020)
Published in PLoS biology (17.12.2020)
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Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
Zhong, Zhou, Ning, Jiying, Boggs, Emerson A, Jang, Sooin, Wallace, Callen, Telmer, Cheryl, Bruchez, Marcel P, Ahn, Jinwoo, Engelman, Alan N, Zhang, Peijun, Watkins, Simon C, Ambrose, Zandrea
Published in mBio (23.03.2021)
Published in mBio (23.03.2021)
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SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis
Diedrich, Collin R, Rutledge, Tara, Maiello, Pauline, Baranowski, Tonilynn M, White, Alexander G, Borish, H. Jacob, Karell, Paul, Hopkins, Forrest, Brown, Jessica, Fortune, Sarah M, Flynn, JoAnne L, Ambrose, Zandrea, Lin, Philana Ling
Published in PLoS pathogens (30.07.2020)
Published in PLoS pathogens (30.07.2020)
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Deep analysis of CD4 T cells in the rhesus CNS during SIV infection
Elizaldi, Sonny R, Verma, Anil, Ma, Zhong-Min, Ott, Sean, Rajasundaram, Dhivyaa, Hawes, Chase E, Lakshmanappa, Yashavanth Shaan, Cottrell, Mackenzie L, Kashuba, Angela D M, Ambrose, Zandrea, Lifson, Jeffrey D, Morrison, John H, Iyer, Smita S
Published in PLoS pathogens (07.12.2023)
Published in PLoS pathogens (07.12.2023)
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Human Immunodeficiency Virus Type 1 Capsid Mutation N74D Alters Cyclophilin A Dependence and Impairs Macrophage Infection
AMBROSE, Zandrea, LEE, Kyeongeun, KEWALRAMANI, Vineet N, NDJOMOU, Jean, HONGZHAN XU, OZTOP, Ilker, MATOUS, James, TAKEMURA, Taichiro, UNUTMAZ, Derya, ENGELMAN, Alan, HUGHES, Stephen H
Published in Journal of Virology (01.04.2012)
Published in Journal of Virology (01.04.2012)
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APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants
Dwivedi, Richa, Wang, Youya, Kline, Christopher, Fischer, Douglas K., Ambrose, Zandrea
Published in Frontiers in virology (online) (14.07.2022)
Published in Frontiers in virology (online) (14.07.2022)
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Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay
Xu, Hongzhan, Franks, Tamera, Gibson, Gregory, Huber, Kelly, Rahm, Nadia, Strambio De Castillia, Caterina, Luban, Jeremy, Aiken, Christopher, Watkins, Simon, Sluis-Cremer, Nicolas, Ambrose, Zandrea
Published in Retrovirology (09.07.2013)
Published in Retrovirology (09.07.2013)
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Journal Article
SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV- Mycobacterium tuberculosis Co-Infection
Tisthammer, Kaho H, Kline, Christopher, Rutledge, Tara, Diedrich, Collin R, Ita, Sergio, Lin, Philana Ling, Ambrose, Zandrea, Pennings, Pleuni S
Published in Viruses (29.12.2021)
Published in Viruses (29.12.2021)
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A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host
Feder, Alison F, Kline, Christopher, Polacino, Patricia, Cottrell, Mackenzie, Kashuba, Angela D M, Keele, Brandon F, Hu, Shiu-Lok, Petrov, Dmitri A, Pennings, Pleuni S, Ambrose, Zandrea
Published in PLoS pathogens (01.05.2017)
Published in PLoS pathogens (01.05.2017)
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Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model
Kline, Christopher, Ndjomou, Jean, Franks, Tamera, Kiser, Rebecca, Coalter, Vicky, Smedley, Jeremy, Piatak, Jr, Michael, Mellors, John W, Lifson, Jeffrey D, Ambrose, Zandrea
Published in PloS one (18.12.2013)
Published in PloS one (18.12.2013)
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macaque model of HIV-1 infection
Hatziioannou, Theodora, Ambrose, Zandrea, Chung, Nancy P.Y, Piatak, Michael Jr, Yuan, Fang, Trubey, Charles M, Coalter, Vicky, Kiser, Rebecca, Schneider, Doug, Smedley, Jeremy, Pung, Rhonda, Gathuka, Mercy, Estes, Jacob D, Veazey, Ronald S, KewalRamani, Vineet N, Lifson, Jeffrey D, Bieniasz, Paul D
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Virus Containing Human Immunodeficiency Virus Reverse Transcriptase
BOLTZ, Valerie F, AMBROSE, Zandrea, KEARNEY, Mary F, WEI SHAO, KEWALRAMANI, Vineet N, MALDARELLI, Frank, MELLORS, John W, COFFIN, John M
Published in Journal of Virology (01.12.2012)
Published in Journal of Virology (01.12.2012)
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Journal Article
Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy
KEARNEY, Mary, SPINDLER, Jon, ARNBROSE, Zandrea, WEI SHAO, MALDARELLI, Frank, PALMER, Sarah, HU, Shiu-Lok, LIFSON, Jeffrey D, KEWALRARNANI, Vineet N, MELLORS, John W, COFFIN, John M
Published in Journal of Virology (01.01.2011)
Published in Journal of Virology (01.01.2011)
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