FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma
Trautmann, Marcel, Menzel, Jasmin, Bertling, Christian, Cyra, Magdalene, Isfort, Ilka, Steinestel, Konrad, Elges, Sandra, Grünewald, Inga, Altvater, Bianca, Rossig, Claudia, Fröhling, Stefan, Hafner, Susanne, Simmet, Thomas, Åman, Pierre, Wardelmann, Eva, Huss, Sebastian, Hartmann, Wolfgang
Published in Clinical cancer research (15.10.2017)
Published in Clinical cancer research (15.10.2017)
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Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors
Forni, Claudia, Minuzzo, Mario, Virdis, Emanuela, Tamborini, Elena, Simone, Matteo, Tavecchio, Michele, Erba, Eugenio, Grosso, Federica, Gronchi, Alessandro, Aman, Pierre, Casali, Paolo, D'Incalci, Maurizio, Pilotti, Silvana, Mantovani, Roberto
Published in Molecular cancer therapeutics (01.02.2009)
Published in Molecular cancer therapeutics (01.02.2009)
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Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153
Jauhiainen, Alexandra, Thomsen, Christer, Strömbom, Linda, Grundevik, Pernilla, Andersson, Carola, Danielsson, Anna, Andersson, Mattias K, Nerman, Olle, Rörkvist, Linda, Ståhlberg, Anders, Åman, Pierre
Published in PloS one (09.04.2012)
Published in PloS one (09.04.2012)
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A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma
Tomić, Tajana Tešan, Olausson, Josefin, Wilzén, Annica, Sabel, Magnus, Truvé, Katarina, Sjögren, Helene, Dósa, Sándor, Tisell, Magnus, Lannering, Birgitta, Enlund, Fredrik, Martinsson, Tommy, Åman, Pierre, Abel, Frida
Published in PloS one (2017)
Published in PloS one (2017)
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Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone
Isfort, Ilka, Elges, Sandra, Cyra, Magdalene, Berthold, Ruth, Renner, Marcus, Mechtersheimer, Gunhild, Åman, Pierre, Larsson, Olle, Ratner, Nancy, Hafner, Susanne, Simmet, Thomas, Schliemann, Christoph, Rossig, Claudia, Dirksen, Uta, Grünewald, Inga, Wardelmann, Eva, Huss, Sebastian, Hartmann, Wolfgang, Trautmann, Marcel
Published in Scientific reports (23.12.2019)
Published in Scientific reports (23.12.2019)
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Requirement for YAP1 signaling in myxoid liposarcoma
Trautmann, Marcel, Cheng, Ya‐Yun, Jensen, Patrizia, Azoitei, Ninel, Brunner, Ines, Hüllein, Jennifer, Slabicki, Mikolaj, Isfort, Ilka, Cyra, Magdalene, Berthold, Ruth, Wardelmann, Eva, Huss, Sebastian, Altvater, Bianca, Rossig, Claudia, Hafner, Susanne, Simmet, Thomas, Ståhlberg, Anders, Åman, Pierre, Zenz, Thorsten, Lange, Undine, Kindler, Thomas, Scholl, Claudia, Hartmann, Wolfgang, Fröhling, Stefan
Published in EMBO molecular medicine (01.05.2019)
Published in EMBO molecular medicine (01.05.2019)
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Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma
Berthold, Ruth, Isfort, Ilka, Erkut, Cihan, Heinst, Lorena, Grünewald, Inga, Wardelmann, Eva, Kindler, Thomas, Åman, Pierre, Grünewald, Thomas G. P., Cidre-Aranaz, Florencia, Trautmann, Marcel, Fröhling, Stefan, Scholl, Claudia, Hartmann, Wolfgang
Published in Oncogenesis (New York, NY) (22.04.2022)
Published in Oncogenesis (New York, NY) (22.04.2022)
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Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma
Steinmann, Sara, Gali-Muhtasib, Hala, Huebner, Kerstin, Al-Halabi, Racha, Abou Merhi, Raghida, Aman, Pierre, Agaimy, Abbas, Haller, Florian, Schneider-Stock, Regine
Published in Cancer letters (28.10.2015)
Published in Cancer letters (28.10.2015)
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Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma
Ståhlberg, Anders, Kåbjörn Gustafsson, Christina, Engtröm, Katarina, Thomsen, Christer, Dolatabadi, Soheila, Jonasson, Emma, Li, Chieh-Yuan, Ruff, David, Chen, Shiaw-Min, Åman, Pierre
Published in PloS one (2014)
Published in PloS one (2014)
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SRC inhibition represents a potential therapeutic strategy in liposarcoma
Sievers, Elisabeth, Trautmann, Marcel, Kindler, Dagmar, Huss, Sebastian, Gruenewald, Inga, Dirksen, Uta, Renner, Marcus, Mechtersheimer, Gunhild, Pedeutour, Florence, Åman, Pierre, Nishio, Jun, Schildhaus, Hans‐Ulrich, Kirfel, Jutta, Schirmacher, Peter, Wardelmann, Eva, Buettner, Reinhard, Hartmann, Wolfgang
Published in International journal of cancer (01.12.2015)
Published in International journal of cancer (01.12.2015)
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Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation
de Graaff, Marieke A, Yu, Jamie S E, Beird, Hannah C, Ingram, Davis R, Nguyen, Theresa, Juehui Liu, Jeffrey, Bolshakov, Svetlana, Szuhai, Károly, Åman, Pierre, Torres, Keila E, Lev, Dina, Nielsen, Torsten O, Bovée, Judith V M G, Lazar, Alexander J, Somaiah, Neeta
Published in Laboratory investigation (01.08.2016)
Published in Laboratory investigation (01.08.2016)
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HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo
Safavi, Setareh, Järnum, Sofia, Vannas, Christoffer, Udhane, Sameer, Jonasson, Emma, Tomic, Tajana Tesan, Grundevik, Pernilla, Fagman, Henrik, Hansson, Magnus, Kalender, Zeynep, Jauhiainen, Alexandra, Dolatabadi, Soheila, Stratford, Eva Wessel, Myklebost, Ola, Eriksson, Mikael, Stenman, Göran, Schneider-Stock, Regine, Ståhlberg, Anders, Åman, Pierre
Published in Oncotarget (05.01.2016)
Published in Oncotarget (05.01.2016)
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The Myxoid/Round Cell Liposarcoma Fusion Oncogene FUS-DDIT3 and the Normal DDIT3 Induce a Liposarcoma Phenotype in Transfected Human Fibrosarcoma Cells
Engström, Katarina, Willén, Helena, Kåbjörn-Gustafsson, Christina, Andersson, Carola, Olsson, Marita, Göransson, Melker, Järnum, Sofia, Olofsson, Anita, Warnhammar, Elisabeth, Åman, Pierre
Published in The American journal of pathology (01.05.2006)
Published in The American journal of pathology (01.05.2006)
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The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
Andersson, Mattias K, Ståhlberg, Anders, Arvidsson, Yvonne, Olofsson, Anita, Semb, Henrik, Stenman, Göran, Nilsson, Ola, Aman, Pierre
Published in BMC cell biology (11.07.2008)
Published in BMC cell biology (11.07.2008)
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JAK–STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma
Dolatabadi, Soheila, Jonasson, Emma, Lindén, Malin, Fereydouni, Bentolhoda, Bäcksten, Karin, Nilsson, Malin, Martner, Anna, Forootan, Amin, Fagman, Henrik, Landberg, Göran, Åman, Pierre, Ståhlberg, Anders
Published in International journal of cancer (15.07.2019)
Published in International journal of cancer (15.07.2019)
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Quantitative PCR Analysis of DNA, RNAs, and Proteins in the Same Single Cell
STAHLBERG, Anders, THOMSEN, Christer, RUFF, David, AMAN, Pierre
Published in Clinical chemistry (Baltimore, Md.) (01.12.2012)
Published in Clinical chemistry (Baltimore, Md.) (01.12.2012)
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Identification of genomic binding sites and direct target genes for the transcription factor DDIT3/CHOP
Osman, Ayman, Lindén, Malin, Österlund, Tobias, Vannas, Christoffer, Andersson, Lisa, Escobar, Mandy, Ståhlberg, Anders, Åman, Pierre
Published in Experimental cell research (01.01.2023)
Published in Experimental cell research (01.01.2023)
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The first European interdisciplinary ewing sarcoma research summit
Kovar, Heinrich, Alonso, Javier, Aman, Pierre, Aryee, Dave N T, Ban, Jozef, Burchill, Sue A, Burdach, Stefan, De Alava, Enrique, Delattre, Olivier, Dirksen, Uta, Fourtouna, Argyro, Fulda, Simone, Helman, Lee J, Herrero-Martin, David, Hogendoorn, Pancras C W, Kontny, Udo, Lawlor, Elizabeth R, Lessnick, Stephen L, Llombart-Bosch, Antonio, Metzler, Markus, Moriggl, Richard, Niedan, Stephan, Potratz, Jenny, Redini, Françoise, Richter, Günther H S, Riedmann, Lucia T, Rossig, Claudia, Schäfer, Beat W, Schwentner, Raphaela, Scotlandi, Katia, Sorensen, Poul H, Staege, Martin S, Tirode, Franck, Toretsky, Jeffrey, Ventura, Selena, Eggert, Angelika, Ladenstein, Ruth
Published in Frontiers in oncology (2012)
Published in Frontiers in oncology (2012)
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FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in sarcoma
Lindén, Malin, Vannas, Christoffer, Österlund, Tobias, Andersson, Lisa, Osman, Ayman, Escobar, Mandy, Fagman, Henrik, Ståhlberg, Anders, Åman, Pierre
Published in Molecular oncology (01.07.2022)
Published in Molecular oncology (01.07.2022)
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Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development
Ranji, Parmida, Jonasson, Emma, Andersson, Lisa, Filges, Stefan, Luna Santamaría, Manuel, Vannas, Christoffer, Dolatabadi, Soheila, Gustafsson, Anna, Myklebost, Ola, Håkansson, Joakim, Fagman, Henrik, Landberg, Göran, Åman, Pierre, Ståhlberg, Anders
Published in Journal of translational medicine (26.04.2024)
Published in Journal of translational medicine (26.04.2024)
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